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  1. Higher cefazolin concentrations in synovial fluid with intraosseous regional prophylaxis in knee arthroplasty: a randomized controlled trial

    Background

    Prophylactic antibiotics reduce the risk of periprosthetic joint infection. However, conventional systemic administration may not provide...

    **gyu Zhang, Guangxiang Chen, ... Renjie Xu in Archives of Orthopaedic and Trauma Surgery
    Article 30 October 2023
  2. Synovial fluid pH is as specific as synovial leukocyte count but less sensitive for the diagnosis of chronic prosthetic joint infection

    Background

    Synovial fluid markers (synovial leukocyte count and differential) have been shown to be most accurate in diagnosing prosthetic joint...

    Christoph Theil, Thomas Ackmann, ... Sebastian Klingebiel in Journal of Orthopaedics and Traumatology
    Article Open access 19 November 2022
  3. It can be unnecessary to combine common synovial fluid analysis and alpha-defensin tests for periprosthetic joint infection diagnosis

    Background

    Periprosthetic joint infection is a serious complication after total joint arthroplasty. Despite that alpha-defensin was used as diagnostic...

    Hao Li, Rui Li, ... Fangzheng Zhu in BMC Musculoskeletal Disorders
    Article Open access 29 June 2023
  4. Definition of follicular helper T cell and cytokines expression in synovial fluid of rheumatoid arthritis

    Objective

    This study aimed to assess the role of synovial fluid (SF) CD4 + T, CD19 + B, follicular helper cells (Tfh), and cytokines in the pathogenesis...

    Shaowei Pan, **aoyu **ao, ... **aoli Zhang in Clinical Rheumatology
    Article 04 October 2023
  5. TNF-Ī± in the serum and synovial fluid of patients with rheumatoid arthritis: correlation with sonographic parameters: a cross-sectional study

    Background

    Rheumatoid arthritis (RA) is a chronic, inflammatory joint condition characterized by overproduction of pro-inflammatory cytokines. We...

    Aya El Hassany, Samar Tharwat, ... Asmaa Farouk Enein in Egyptian Rheumatology and Rehabilitation
    Article Open access 07 May 2024
  6. The preferred technique for knee synovium biopsy and synovial fluid arthrocentesis

    For knee osteoarthritis and related conditions, analysis of biomarkers hold promise to improve early diagnosis and/or offer patient-specific...

    Marie Fuentes--Braesch, Gabriƫlle J. M. Tuijthof, ... Kaj S. Emanuel in Rheumatology International
    Article 13 December 2022
  7. Synovial fluid monocyte-to-lymphocyte ratio in knee osteoarthritis patients predicts patient response to conservative treatment: a retrospective cohort study

    Background

    Biomarkers that predict the treatment response in patients with knee osteoarthritis are scarce. This study aimed to investigate the...

    Jong Min Lee, Sumin Lim, ... Jae-Young Park in BMC Musculoskeletal Disorders
    Article Open access 14 May 2024
  8. Dithiotreitol pre-treatment of synovial fluid samples improves microbiological counts in peri-prosthetic joint infection

    Purpose

    Synovial fluid cultures of periprosthetic joint infections (PJI) may be limited by bacteria living in the fluids as biofilm-aggregates. The...

    Lorenzo Drago, Delia RomanĆ², ... Carlo Luca RomanĆ² in International Orthopaedics
    Article Open access 22 February 2023
  9. Characteristics of the synovial microenvironment and synovial mesenchymal stem cells with hip osteoarthritis of different bone morphologies

    Background

    Variations in bone morphology in patients with hip osteoarthritis (HOA) can be broadly categorized into three types: atrophic,...

    Yang Yang, Hideyuki Koga, ... Kazumasa Miyatake in Arthritis Research & Therapy
    Article Open access 10 January 2024
  10. Physical activity increases synovial fluid in ankle tendon sheaths: an adjustment of MR Criteria is needed

    Objectives

    To compare the amount of fluid in synovial sheaths of the ankle before and after running. Our hypothesis was that this amount would...

    Michel De Maeseneer, Seema Doering, ... Inneke Willekens in Surgical and Radiologic Anatomy
    Article 17 January 2023
  11. Correlation Between Synovial Fluid Levels of Matrix Metalloproteinaseā€™s (MMP-1, MMP-3, and MMP-9) and TNF-Ī± with the Severity of Osteoarthritis Knee in Rural Indian Population

    Background

    In India, 22% to 39% of the ageing population suffers from degenerative knee osteoarthritis (OA), making it the most prevalent joint...

    Sunil Kumar, Harish Kumar, ... Vyutpanna Mishra in Indian Journal of Orthopaedics
    Article 04 September 2023
  12. Serum versus synovial fluid interleukin-6 for periprosthetic joint infection diagnosis: a systematic review and meta-analysis of 30 diagnostic test accuracy studies

    Background

    Early and accurate detection of periprosthetic joint infection (PJI) after hip and/or knee arthroplasty remains challenging. This...

    Jian Li, Qian Zhou, Biquan Deng in Journal of Orthopaedic Surgery and Research
    Article Open access 24 December 2022
  13. Synovial Fluid Analysis and The Evaluation of Patients With Arthritis

    This book reviews the major components of synovial fluid analysis, with an emphasis on crystal recognition. Synovial fluid analysis is the required...

    Brian F. Mandell
    Textbook 2022
  14. The Persistency and Visibility of Synovial Fluid Crystals After at Least 10 Days in Refrigerator by Light and Polarized Microscopy

    Introduction

    Synovial fluid (SF) analysis is one of the most important tests used in approach to arthritis and is necessary for rheumatology...

    Saeedeh Shenavandeh in Indian Journal of Orthopaedics
    Article 11 June 2023
  15. The concordance between preoperative aspiration and intraoperative synovial fluid culture results: intraoperative synovial fluid re-cultures are necessary whether the preoperative aspiration culture is positive or not

    Aims

    Preoperative aspiration culture and intraoperative cultures play pivotal roles in periprosthetic joint infection (PJI) diagnosis and pathogen...

    Hao Li, Chi Xu, ... Jiying Chen in BMC Infectious Diseases
    Article Open access 29 September 2021
  16. Identification of plasma and urinary inflammatory markers in severe knee osteoarthritis: Relations with synovial fluid markers

    Background

    This study aimed to identify plasma and urinary cytokines as potential biomarkers for severe knee osteoarthritis (OA). It also...

    Ji-Sun Shin, Hyobeom Lee, ... Si Young Song in Knee Surgery & Related Research
    Article Open access 21 May 2024
  17. Association of HMGB1 levels in synovial fluid with the severity of temporomandibular joint osteoarthritis

    Background

    HMGB1 usually serves as a damage-associated molecular pattern (DAMP) molecule (also known as alarmin) that regulates the inflammatory and...

    Bo Shao, Yingjie Xu, ... Zhong-cheng Gong in BMC Musculoskeletal Disorders
    Article Open access 11 March 2023
  18. Equine osteoarthritis modifies fatty acid signatures in synovial fluid and its extracellular vesicles

    Background

    Individual fatty acids (FAs) and their derivatives (lipid mediators) with pro-inflammatory or dual anti-inflammatory and pro-resolving...

    Anne-Mari Mustonen, Nina Lehmonen, ... Petteri Nieminen in Arthritis Research & Therapy
    Article Open access 09 March 2023
  19. Peptidoglycan in osteoarthritis synovial tissue is associated with joint inflammation

    Objectives

    Peptidoglycan (PG) is an arthritogenic bacterial cell wall component whose role in human osteoarthritis is poorly understood. The purpose...

    Meaghan N Holub, Amanda Wahhab, ... Robert B Lochhead in Arthritis Research & Therapy
    Article Open access 27 March 2024
  20. Assessment of serum and synovial fluid MMP-3 and MPO as biomarkers for psoriatic arthritis and their relation to disease activity indices

    Research on biomarkers for the diagnosis and monitoring of psoriatic arthritis (PsA) is ongoing. The purpose of this study was to assess the...

    Mariela Geneva-Popova, Stanislava Popova-Belova, ... Anastas Batalov in Rheumatology International
    Article 16 June 2022
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