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Management of Midface Deficiency in Syndromic Craniosynostosis with Lefort III Distraction Osteogenesis, Outcomes, and Pitfalls
BackgroundSyndromic craniosynostosis is characterized by premature fusion of cranial sutures resulting in midface deficiency. Lefort III Distraction...
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Frequency and predictors of concurrent complications in multi-suture release for syndromic craniosynostosis
PurposeUnderstanding the complication profile of craniosynostosis surgery is important, yet little is known about complication co-occurrence in...
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Skeletal expansion via craniofacial distraction osteogenesis technique in syndromic craniosynostosis: impact on ophthalmic parameters
BackgroundThis study aims to compare the changes in ophthalmic parameters among syndromic craniosynostosis patients who underwent craniofacial...
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The current understanding of germline predisposition in non-syndromic sagittal craniosynostosis: a systematic review
PurposeThe objective of this literature review was to provide a comprehensive and up-to-date overview of the current understanding of the genetic...
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Early posterior vault distraction osteogenesis changes the syndromic craniosynostosis treatment paradigm: long-term outcomes of a 23-year cohort study
BackgroundEarly surgical management of syndromic craniosynostosis varies widely between centers, with patients typically undergoing multiple...
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Prior fronto-orbital advancement associated with complications from transcranial midface surgery in patients with syndromic craniosynostosis
PurposeOur center adopted posterior vault distraction osteogenesis (PVDO) as a first-line intervention for cranial expansion in syndromic...
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Utilization of carbonated calcium phosphate cement for contouring cranioplasty in patients with syndromic craniosynostosis
PurposeCarbonated calcium phosphate (CCP) cement is an alloplastic material which has been increasingly utilized for cranioplasty reconstruction;...
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The effect of continuous positive airway pressure on obstructive sleep apnea in children with syndromic craniosynostosis
BackgroundObstructive sleep apnea (OSA) is common in children with syndromic craniosynostosis (SC). However, objective data on the treatment of OSA...
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Facial skeleton dysmorphology in syndromic craniosynostosis: differences between FGFR2 and no-FGFR2-related syndromes and relationship with skull base and facial sutural patterns
PurposeTo assess the role of FGFR2 mutations and sutural synostotic patterns on facial skeleton dysmorphology in children with syndromic...
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Differential diagnosis of syndromic craniosynostosis: a case series
PurposeSyndromic craniosynostosis is a rare genetic disease caused by premature fusion of one or multiple cranial sutures combined with malformations...
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The impact of obstructive sleep apnea on growth in patients with syndromic and complex craniosynostosis: a retrospective study
Given the high prevalence of OSA in children with syndromic and complex craniosynostosis (SCC) and the consequences of untreated OSA, it is important...
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Neurocognitive outcomes of children with non-syndromic single-suture craniosynostosis
While the focus of craniosynostosis surgery is to improve head shape, neurocognitive sequelae are common and are incompletely understood....
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Posterior cranial vault distraction in children with syndromic craniosynostosis: the era of biodegradable materials—a comprehensive review of the literature and proposed novel global application
Distraction osteogenesis is utilized to increase intracranial volume in the treatment of restrictive pathologies, most commonly syndromic synostosis....
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ERN CRANIO patient coverage of craniosynostosis in Europe
BackgroundAgainst the backdrop of the European Directive on patients’ rights in cross-border healthcare, 24 European Reference Networks (ERNs) were...
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ERF-related craniosynostosis and surgical management in the paediatric cohort
IntroductionERF mutation is one of the most recently identified genetic aberrations associated with syndromic craniosynostosis. Data on the pattern...
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Patterns, trends, and factors influencing hospitalizations for craniosynostosis in Western Australia. A population-based study
Understanding hospital service use among children with a diagnosis of craniosynostosis (CS) is important to improve services and outcomes. This study...
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Management of ventriculomegaly in pediatric patients with syndromic craniosynostosis: a single center experience
IntroductionManagement of ventriculomegaly in pediatric patients with syndromic craniosynostosis (SC) requires understanding the underlying...
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Evaluation of neurocognitive and social developments after craniosynostosis surgery
ObjectiveThe study focused on assessing the potential neurocognitive and social developmental issues in children with non-syndromic craniosynostosis...
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The awareness of treatment plans of craniosynostosis: guideline for patient and family version
BackgroundFunctional and structural complexities associated with craniosynostosis present challenges for families of affected individuals....
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A diffusion tensor imaging analysis of white matter microstructures in non-operated craniosynostosis patients
PurposeIn 7 to 15-year-old operated syndromic craniosynostosis patients, we have shown the presence of microstructural anomalies in brain white...
