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Hyperhidrosis: A Central Nervous Dysfunction of Sweat Secretion
Hyperhidrosis (HH) is a central nervous dysfunction characterized by abnormally increased sweating due to a central dysregulation of sweat secretion....
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Changes of sweat gland function in type 2 diabetes mellitus patients with peripheral neuropathy
BackgroundMillions of people suffer from diabetes mellitus. Most of them endure diabetes peripheral neuropathy (DPN) at the same time.
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NECTIN4 expression in sebaceous and sweat gland carcinoma
BackgroundSebaceous carcinoma and sweat gland carcinoma (malignant tumours with apocrine and eccrine differentiation) are rare malignant adnexal...
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Small molecules facilitate single factor-mediated sweat gland cell reprogramming
BackgroundLarge skin defects severely disrupt the overall skin structure and can irreversibly damage sweat glands (SG), thus impairing the skin’s...
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Differential distribution and genetic determination of eccrine sweat glands and hair follicles in the volar skin of C57BL/6 mice and SD rats
BackgroundEccrine sweat glands (ESGs) and hair follicles (HFs) are the prominent skin appendages regulating human body temperature. C57BL/6 mice and...
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The relationship between serum 25‐hydroxyvitamin-D level and sweat function in patients with type 2 diabetes mellitus
AimsThe objective of this study is to explore the relationship between serum 25‐hydroxyvitamin-D(25-(OH) 2 D 3 ) level and sweat function in patients...
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PAI1 inhibits the pathogenesis of primary focal hyperhidrosis by targeting CHRNA1
BackgroundPrimary focal hyperhidrosis (PFH) may be attributed to the up-regulation of the cholinergic receptor nicotinic alpha 1 subunit (CHRNA1) in...
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Do not break a sweat: avoiding pitfalls in the diagnosis of sweat gland tumors
The group of malignant sweat gland neoplasms is characterized by a wide biologic spectrum, including tumors with indolent behavior, low-grade...
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Apocrine hydroadenoma mimicking a Morton’s neuroma: a rare differential diagnosis
A 62-year-old woman, with neuropathic pain and paresthesia in her right forefoot, showed a circumscribed soft tissue swelling on the sole between the...
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Lumacaftor/ivacaftor in cystic fibrosis: effects on glucose metabolism and insulin secretion
PurposeThe question whether the new cystic fibrosis transmembrane conductance regulator (CFTR) modulator drugs aimed at restoring CFTR protein...
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Eccrine Porocarcinoma of Dorsum of Nose: A Rare Case Report
Eccrine porocarcinoma (EPC) is an uncommon malignant tumor derived from the eccrine sweat glands. Because of its various pathological features, it is...
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Image-based β-adrenergic sweat rate assay captures minimal cystic fibrosis transmembrane conductance regulator function
BackgroundThere is a need to prognosticate the severity of cystic fibrosis (CF) detected by newborn screening (NBS) by early assessment of CF...
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Anatomical proposal of local anesthesia injection for median nerve block in treating hyperhidrosis with botulinum neurotoxin
IntroductionHyperhidrosis, causing excessive sweat, can be treated with Botulinum neurotoxin injection. Botulinum toxin, an effective and safe...
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Role of zinc in health and disease
This review provides a concise overview of the cellular and clinical aspects of the role of zinc, an essential micronutrient, in human physiology and...
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Seasonal Heat Acclimatisation in Healthy Adults: A Systematic Review
BackgroundPhysiological heat adaptations can be induced following various protocols that use either artificially controlled (i.e. acclimation) or...
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Intraoperative Hypertonic Saline Irrigation Preventing Seroma Formation in the Treatment of Axillary Bromhidrosis
PurposeSubcutaneous seroma formation (SF) is commonly seen after axillary bromhidrosis surgeries and its treatment can be challenging and long....
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Cystic fibrosis and CFTR-related disorder with electrolyte imbalance at diagnosis: clinical features and outcome in an Italian cohort
There is limited information available on the clinical data, sweat test trends, and outcomes of individuals with cystic fibrosis (CF) who present...
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Reappraisal and literature review of primary cutaneous cribriform apocrine carcinoma
Primary cutaneous cribriform apocrine carcinoma (PCCAC) is an exceedingly rare sweat gland carcinoma. Clinically, it most often presents as a...
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Treatment of Frey Syndrome with Botulinum Toxin-A: A Practical Approach from Minor’s Test to Injection
IntroductionFrey's syndrome, described by Lucy Frey in 1923, is a unique condition characterized by sweating, flushing, and reddening as a direct...
