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Showing 1-13 of 13 results

  1. Suzuki–Miyaura cross-couplings for alkyl boron reagent: recent developments—a review

    In the history of catalysis and organic synthesis, boric chemistry has been developed into one of the most varied and practical disciplines. Several...

    Adnan Ahmed, Irfan Mushtaq, Sampath Chinnam in Future Journal of Pharmaceutical Sciences
    Article Open access 11 August 2023

  2. Small peptide-based GLP-1R ligands: an approach to reduce the kidney uptake of radiolabeled GLP-1R-targeting agents?

    Aim

    Elevated kidney uptake in insulinoma patients remains a major limitation of radiometallated exendin-derived ligands of the glucagon-like peptide 1...

    Veronika Barbara Felber, Hans-Jürgen Wester in EJNMMI Radiopharmacy and Chemistry
    Article Open access 25 August 2021

  3. An overview of recent progress in modern synthetic approach—combinatorial synthesis

    Background

    In recent times, a powerful tool of combinatorial synthesis has been used for the preparation of large chemical entities through a small...

    Chandravadivelu Gopi, Gudapati Krupamai, ... Magharla Dasaratha Dhanaraju in Beni-Suef University Journal of Basic and Applied Sciences
    Article Open access 26 November 2020

  4. Biological activity and molecular docking studies of some new quinolines as potent anticancer agents

    Abstract

    The objective of this study is to investigate the antiproliferative and cytotoxic properties and the action mechanism of substituted...

    Tuğba Kul Köprülü, Salih Ökten, ... Osman Çakmak in Medical Oncology
    Article 19 June 2021

  5. Improved synthesis of SV2A targeting radiotracer [11C]UCB-J

    Introduction

    [ 11 C]UCB-J is a tracer developed for PET (positron emission tomography) that has high affinity towards synaptic vesicle glycoprotein 2A...

    Johanna Rokka, Eva Schlein, Jonas Eriksson in EJNMMI Radiopharmacy and Chemistry
    Article Open access 29 November 2019

  6. Inactivation of the CIC-DUX4 oncogene through P300/CBP inhibition, a therapeutic approach for CIC-DUX4 sarcoma

    CIC-DUX4 sarcoma (CDS) is a highly aggressive and metastatic small round type of predominantly pediatric sarcoma driven by a fusion oncoprotein...

    Darko Bosnakovski, Elizabeth T. Ener, ... Michael Kyba in Oncogenesis
    Article Open access 12 October 2021

  7. Closing the gap between 19F and 18F chemistry

    Positron emission tomography (PET) has become an invaluable tool for drug discovery and diagnosis. The positron-emitting radionuclide fluorine-18 is...

    Javier Ajenjo, Gianluca Destro, ... Véronique Gouverneur in EJNMMI Radiopharmacy and Chemistry
    Article Open access 25 September 2021

  8. Preclinical PET Studies of [11C]UCB-J Binding in Minipig Brain

    Purpose

    Loss of neuronal synapse function is associated with a number of brain disorders. The [ 11 C]UCB-J positron emission tomography (PET) tracer...

    Majken Borup Thomsen, Anna Christina Schacht, ... Anne M. Landau in Molecular Imaging and Biology
    Article 08 June 2020

  10. 700-nm Zwitterionic Near-Infrared Fluorophores for Dual-Channel Image-Guided Surgery

    Purpose

    The purpose of this study was to develop a family of 700-nm zwitterionic pentamethine indocyanine near-infrared fluorophores that would permit...

    Hoon Hyun, Maged Henary, ... Hak Soo Choi in Molecular Imaging and Biology
    Article 18 June 2015
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