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Association of emotional and behavioral problems with the development of the substantia nigra, subthalamic nucleus, and red nucleus volumes and asymmetries from childhood to adolescence: A longitudinal cohort study
The substantia nigra (SN), subthalamic nucleus (STN), and red nucleus (RN) have been widely studied as important biomarkers of degenerative diseases....
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Overlap** stimulation of subthalamic nucleus and dentato-rubro-thalamic tract in Parkinson’s disease after deep brain stimulation
BackgroundDeep brain stimulation (DBS) of the subthalamic nucleus (STN) reduces tremor, rigidity, and akinesia. According to the literature, the...
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Deep brain stimulation of the subthalamic nucleus for a patient with drug resistant juvenile myoclonic epilepsy: 1 year follow-up
BackgroundDrug-resistant juvenile myoclonic epilepsy (DR-JME) remains a significant challenge in neurology. Traditional management strategies often...
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Deep brain stimulation of the subthalamic nucleus in severe Parkinson’s disease: relationships between dual-contact topographic setting and 1-year worsening of speech and gait
BackgroundSubthalamic nucleus (STN) deep brain stimulation (DBS) alleviates severe motor fluctuations and dyskinesia in Parkinson’s disease, but may...
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Volume of tissue activated within subthalamic nucleus and clinical efficacy of deep brain stimulation in Meige syndrome
ObjectiveThe clinical efficacy of deep brain stimulation (DBS) relies on the optimal electrode placement in a large extent. Subthalamic nucleus (STN)...
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A multicenter double-blind randomized crossover study comparing the impact of dorsal subthalamic nucleus deep brain stimulation versus standard care on apathy in Parkinson’s disease: a study protocol
BackgroundNeuroimaging studies suggest an association between apathy after deep brain stimulation (DBS) and stimulation of the ventral part of the...
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Deep brain stimulation of the subthalamic nucleus to improve symptoms and cognitive functions in patients with refractory obsessive–compulsive disorder: a longitudinal study
There are conflicting results regarding the effect of deep brain stimulation (DBS) of different regions on the cognitive functions of patients with...
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Effects of subthalamic nucleus deep brain stimulation using different frequency programming paradigms on axial symptoms in advanced Parkinson’s disease
BackgroundIn advanced Parkinson’s disease (PD), axial symptoms are common and can be debilitating. Although deep brain stimulation (DBS)...
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Depression history modulates effects of subthalamic nucleus topography on neuropsychological outcomes of deep brain stimulation for Parkinson’s disease
Patients with psychiatric symptoms, such as depression, anxiety, and visual hallucinations, may be at increased risk for adverse effects following...
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Subthalamic nucleus-deep brain stimulation improves autonomic dysfunctions in Parkinson’s disease
BackgroundTo study the effects of subthalamic nucleus-deep brain stimulation (STN-DBS) on autonomic dysfunctions in Parkinson’s disease (PD) patients.
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Subthalamic nucleus deep brain stimulation programming settings do not correlate with Parkinson’s disease severity
BackgroundDeep brain stimulation (DBS) is a well-established treatment for Parkinson’s disease (PD). While the success of DBS is dependent on careful...
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Subthalamic deep brain stimulation in advanced Parkinson’s disease using the STarFix system
BackgroundDeep brain stimulation (DBS) is a well-established and highly effective treatment for patients with medically uncontrolled Parkinson’s...
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Deep brain stimulation of globus pallidus internus and subthalamic nucleus in Parkinson’s disease: a multicenter, retrospective study of efficacy and safety
BackgroundDeep brain stimulation (DBS) is an established therapeutic option in advanced Parkinson’s disease (PD). Literature data and recent...
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Pramipexole modulates fronto-subthalamic pathway in sequential working memory
Brain dopamine may regulate the ability to maintain and manipulate sequential information online. However, the precise role of dopamine remains...
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Long-term effects of bilateral subthalamic nucleus deep brain stimulation on gait disorders in Parkinson’s disease: a clinical-instrumental study
ObjectiveTo assess the long-term effects of bilateral subthalamic nucleus deep brain stimulation (STN-DBS) on gait in a cohort of advanced...
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The effect of subthalamic nucleus deep brain stimulation and dopaminergic treatment on dual-task manual dexterity in Parkinson’s disease
Background and purposeDual-task manual dexterity is required to perform activities of daily living and is affected by cognitive functions. This study...
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Comparison of two segmentation software tools for deep brain stimulation of the subthalamic and ventro-intermedius nuclei
PurposeDeep brain stimulation (DBS) relies on precise targeting of key structures such as the subthalamic nucleus (STN) for Parkinson’s disease (PD)...
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Correlation of active contact location with weight gain after subthalamic nucleus deep brain stimulation: a case series
BackgroundWeight gain (WG) is a frequently reported side effect of subthalamic deep brain stimulation; however, the underlying mechanisms remain...
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Pre-operative cognitive burden as predictor of motor outcome following bilateral subthalamic nucleus deep brain stimulation in Parkinson’s disease
IntroductionThe interrelationship between neurocognitive impairments and motor functions was observed in patients with advanced Parkinson’s disease...
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Generalisation capabilities of machine-learning algorithms for the detection of the subthalamic nucleus in micro-electrode recordings
PurposeMicro-electrode recordings (MERs) are a key intra-operative modality used during deep brain stimulation (DBS) electrode implantation, which...
