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A case of early-stage type 3 gastric neuroendocrine tumor in the upper body of the stomach: is endoscopic resection feasible?
Although gastric neuroendocrine tumors (NETs) are uncommon compared with gastric carcinomas, the incidence of NETs has been recently increasing....
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“Transanal endoscopic microsurgery” with a flexible colonoscope (F-TEM): a new endoscopic treatment for suspicious deep submucosal invasion T1 rectal carcinoma
BackgroundEndoscopic techniques allow resections of deep submucosal invasion rectal carcinoma, but mostly are facing issues such as costs, follow-up...
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Prognostic Benefit of Additional Treatment After Endoscopic Submucosal Dissection for Esophageal Squamous Cell Carcinoma
BackgroundAlthough additional treatment is considered for patients with esophageal squamous cell carcinoma (ESCC) invading into the muscularis mucosa...
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The role of vascular invasion and lymphatic invasion in predicting recurrent thoracic oesophageal squamous cell carcinoma
BackgroundNumerous studies have addressed lymphovascular invasion (LVI) in patients with thoracic oesophageal squamous cell carcinoma (ESCC);...
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A case of early gastric cancer resembling a subepithelial lesion diagnosed by endoscopic ultrasound-guided fine needle aspiration
We present a case of early gastric cancer resembling a subepithelial lesion (GCSEL) derived from the submucosal ectopic gastric glands (SEGGs),...
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A machine learning model based on MRI for the preoperative prediction of bladder cancer invasion depth
ObjectivesTo construct and validate a prediction model based on full-sequence MRI for preoperatively evaluating the invasion depth of bladder cancer.
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Study on the diagnostic value of MDCT extramural vascular invasion in preoperative N staging of gastric cancer patients
BackgroundTo explore the diagnostic value of multidetector computed tomography (MDCT) extramural vascular invasion (EMVI) in preoperative N Staging...
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Local excision of T1 colorectal cancer: good differentiation, absence of lymphovascular invasion, and limited tumor radial infiltration (≤4.25 mm) may allow avoiding radical surgery
BackgroundEarly colorectal cancer (ECC) is defined as T1NXM0 colorectal cancer (CRC). Although a non-negligible number of T1-CRCs presents metastatic...
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Long-term prognosis of curative endoscopic submucosal dissection for early colorectal cancer according to submucosal invasion: a multicenter cohort study
BackgroundEndoscopic submucosal dissection (ESD) can provide a high en bloc resection rate and has been widely applied as curative treatment for...
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Stroma AReactive Invasion Front Areas (SARIFA) predict poor survival in adenocarcinomas of the stomach and gastrooesophageal junction: a validation study
Recently, the presence of “Stroma AReactive Invasion Front Areas” (SARIFA) has been described as a promising adverse prognostic factor in gastric...
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A case of superficial spreading type of poorly differentiated adenocarcinoma of the stomach with invasion to the esophagus
BackgroundInvasion is more likely to occur in gastric cancer affecting larger areas. Poorly differentiated adenocarcinoma tends to invade deep. The...
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A case of endoscopic submucosal dissection for neuroendocrine carcinoma of the esophagus with invasion to the muscularis mucosae
Neuroendocrine carcinoma (NEC) of the esophagus at early-stage is very rare due to its rapidly progression. Here, we reported a case of esophageal...
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Risk stratification for predicting postoperative recurrence of gastric cancer by grade of venous invasion
BackgroundVenous invasion (VI) in pathological examination of surgically resected gastric cancer (GC) may predict postoperative recurrence, but there...
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Additional Treatment Following Noncurative Endoscopic Resection for Esophageal Squamous Cell Carcinoma: A Comparison of Outcomes between Esophagectomy and Chemoradiotherapy
BackgroundEndoscopic resection (ER) has been widely implemented for cT1N0 esophageal squamous cell carcinoma (ESCC). Additional therapy, including...
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Risk of metastatic recurrence after endoscopic resection for esophageal squamous cell carcinoma invading into the muscularis mucosa or submucosa: a multicenter retrospective study
BackgroundWe aimed to elucidate the risk of metastatic recurrence after endoscopic resection (ER) without additional treatment for esophageal...
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Invasive features of superficial oesophageal squamous cell carcinoma—analysis of risk factors for lymph node metastasis
There are currently no studies that have examined the clinicopathological factors in detail, including the histological images of the invasive front,...
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Early gastric cancer with RhoGAP fusion is linked to frequent nodal metastasis and a part of microtubular–mucocellular histology
IntroductionGastric cancer with fusion genes involving the Rho GTPase-activating protein domain (RhoGAP-GC) is mainly included in the genomically...
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Use of Immunostaining for the diagnosis of Lymphovascular invasion in superficial Barrett’s esophageal adenocarcinoma
BackgroundThe prevalence of Barrett’s esophageal adenocarcinoma (BEA) is increasing in Japan. Accurate assessment of lymphovascular invasion (LVI)...
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Primary Malignant Melanoma of Tongue: Rare and Aggressive Malignant Tumor
Primary melanoma of the oral cavity is extremely rare, accounting for 0.2–8% of all melanomas. Lesions arising from mucosal melanocytes occur most...
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A prospective multicenter study of the magnifying endoscopic evaluation of the invasion depth of superficial esophageal cancers
BackgroundTreatment strategies for superficial esophageal squamous cell carcinoma (SESCC) are determined mainly on the basis of the invasion depth....