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Molecular signature of excessive female aggression: study of stressed mice with genetic inactivation of neuronal serotonin synthesis
Aggression is a complex social behavior, critically involving brain serotonin (5-HT) function. The neurobiology of female aggression remains elusive,...
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Serotonergic psychedelic 5-MeO-DMT alters plasticity-related gene expression and generates anxiolytic effects in stressed mice
Serotonergic psychedelics have potential therapeutic effects in treating anxiety and mood disorders, often after a single dose, and are suggested to...
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Pressure–Volume Profiles in Heart Failure Across Sexes and Phenotypes
Studies have shown poor correlation between intra-cardiac pressures and blood volume (BV) measurements including HF. The impact of sex and left...
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Effect of a vapor barrier in combination with active external rewarming for cold-stressed patients in a prehospital setting: a randomized, crossover field study
BackgroundUse of a vapor barrier in the prehospital care of cold-stressed or hypothermic patients aims to reduce evaporative heat loss and accelerate...
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Blood volume in patients likely to be preload responsive: a post hoc analysis of a randomized controlled trial
BackgroundPreload responsive postoperative patients with signs of inadequate organ perfusion are commonly assumed to be hypovolemic and therefore...
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Diaphragm excursions as proxy for tidal volume during spontaneous breathing in invasively ventilated ICU patients
There is a need to monitor tidal volume in critically ill patients with acute respiratory failure, given its relation with adverse clinical outcome....
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How can assessing hemodynamics help to assess volume status?
In critically ill patients, fluid infusion is aimed at increasing cardiac output and tissue perfusion. However, it may contribute to fluid overload...
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Chronic clomipramine treatment increases hippocampal volume in rats exposed to chronic unpredictable mild stress
It is well known that neuroinflammation is closely related to the pathophysiology of depression. Due to individual differences in clinical research,...
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Abnormal heart rate responses to exercise in non-severe COPD: relationship with pulmonary vascular volume and ventilatory efficiency
BackgroundDespite being a prognostic predictor, cardiac autonomic dysfunction (AD) has not been well investigated in chronic obstructive pulmonary...
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Perioperative optimization and profitability (POP) in a high-volume bariatric surgery center
BackgroundCurrently, bariatric surgery is the most effective long-term treatment of obesity. Sleeve gastrectomy (SG) and Roux-en-Y gastric bypass...
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Anthropometric estimators of abdominal fat volume in adults with overweight and obesity
Background/ObjectivesTo evaluate anthropometric measures for the prediction of whole-abdominal adipose tissue volumes V XAT (subcutaneous V SAT ,...
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Non-invasive quantification of pressure–volume loops in patients with Fontan circulation
BackgroundPressure–volume (PV) loops provide comprehensive information of cardiac function, but commonly implies an invasive procedure under general...
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Norepinephrine potentiates the efficacy of volume expansion on mean systemic pressure in septic shock
BackgroundThrough venous contraction, norepinephrine (NE) increases stressed blood volume and mean systemic pressure (Pms) and exerts a “fluid-like”...
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Analogue Mean Systemic Filling Pressure: a New Volume Management Approach During Percutaneous Left Ventricular Assist Device Therapy
The absence of an accepted gold standard to estimate volume status is an obstacle for optimal management of left ventricular assist devices (LVADs)....
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Does higher knee hyperextension in patients with hemiplegia affect lateral and medial meniscus volume in the paretic leg? A cross-sectional study
BackgroundAfter stroke, an abnormal gait pattern gradually leads to knee pain and joint lesions, resulting the gait instability. However, the...
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Circulatory Response to Rapid Volume Expansion and Cardiorespiratory Fitness in Fontan Circulation
The role of dysfunction of the single ventricle in Fontan failure is incompletely understood. We aimed to evaluate hemodynamic responses to preload...
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The impact of perioperative risk factors on long-term survival after radical cystectomy: a prospective, high-volume cohort study
IntroductionRadical cystectomy (RC) is the gold standard for muscle-invasive bladder cancer. Nevertheless, RC is associated with substantial...
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Genetic common variants associated with cerebellar volume and their overlap with mental disorders: a study on 33,265 individuals from the UK-Biobank
Interest in the cerebellum is expanding given evidence of its contributions to cognition and emotion, and dysfunction in various psychopathologies....
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Center-Level Procedure Volume Does Not Predict Failure-to-Rescue After Severe Complications of Oncologic Colon and Rectal Surgery
BackgroundThe relationship between hospital surgical volume and outcome after colorectal cancer surgery has thoroughly been studied. However, few...
