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Showing 1-20 of 2,071 results
  1. Statin intolerance management: a systematic review

    Background

    Statin intolerance is a key barrier to the effective prevention of atherosclerotic cardiovascular disease (ASCVD). Experts do not agree on...

    Alejandra Meza-Contreras, Camila Wenczenovicz, ... Victor M. Montori in Endocrine
    Article 02 December 2022
  2. Statin Intolerance: an Overview of US and International Guidance

    Purpose of Review

    To review recent international and domestic definitions, considerations, and treatment algorithms for statin intolerance, and...

    Mary Katherine Cheeley, Katarina Clegg, ... Laney K. Jones in Current Atherosclerosis Reports
    Article Open access 06 July 2023
  3. A Review of Statin Intolerance: a Focus on Statin-Attributed Muscle Symptoms

    Purpose of Review

    To provide a systematic approach to management of the patient with statin-attributed muscle symptoms.

    Recent Findings ...
    Carl E. Orringer, Jelani K. Grant, Lale Tokgozoglu in Current Atherosclerosis Reports
    Article 24 August 2022
  4. SAMSON and the Nocebo Effect: Management of Statin Intolerance

    Purpose of Review

    Statins are essential medications in the treatment of atherosclerotic cardiovascular disease; however, remain widely underutilized...

    Amrita Krishnamurthy, Corey Bradley, ... Samuel M. Kim in Current Cardiology Reports
    Article 27 June 2022
  5. A mobile health application for patients eligible for statin therapy: app development and qualitative feedback on design and usability

    Background

    Cardiovascular disease is the leading cause of death in the United States (US). Despite the well-recognized efficacy of statins, statin...

    Weidan Cao, Lang Li, ... M. Wesley Milks in BMC Medical Informatics and Decision Making
    Article Open access 19 July 2023
  6. Decoding the Intricacies of Statin-Associated Muscle Symptoms

    Purpose of Review

    Hyperlipidemia is the major cardiovascular morbidity and mortality risk factor. Statins are the first-line treatment for...

    Tara Fallah Rastegar, Imtiaz Ahmed Khan, Lisa Christopher-Stine in Current Rheumatology Reports
    Article 05 April 2024
  7. Evaluating Statin Tolerability in Historically Intolerant Patients After Correcting for Subclinical Hypothyroidism and Vitamin D Insufficiency

    Introduction

    Atherosclerotic cardiovascular disease (ASCVD) is the major cause of morbidity and mortality worldwide. Statins provide primary and...

    Robert Solomon, Premchand Anne, ... James J. Maciejko in High Blood Pressure & Cardiovascular Prevention
    Article 05 September 2022
  8. The Role of Mitochondria in Statin-Induced Myopathy

    Statins represent the primary therapy for combatting hypercholesterolemia and reducing mortality from cardiovascular events. Despite their...

    Gavin Bell, Anastasia Thoma, ... Adam P. Lightfoot in Drug Safety
    Article 16 March 2024
  9. Bempedoic Acid in the Treatment of Patients with Dyslipidemias and Statin Intolerance

    An elevated plasma low-density lipoprotein cholesterol (LDL-C) level is a well-established atherosclerotic cardiovascular disease (ACSVD) risk...

    Andrey V. Susekov, Ludmila A. Korol, Gerald F. Watts in Cardiovascular Drugs and Therapy
    Article 27 January 2021
  10. Statin Intolerance in Clinical Practice

    Purpose of Review

    In our pilot study, we aimed to determine how many patients with the statin intolerance history referred to the specialized center...

    Michaela Snejdrlova, T. Altschmiedova, ... R. Ceska in Current Atherosclerosis Reports
    Article 03 June 2020
  11. Statin withdrawal and health-related quality of life in a primary cardiovascular prevention cohort

    Purpose

    While some work has been done on Health-Related Quality of Life (HRQoL) in statin users, none has focused specifically on statin-associated...

    P. Peyrel, P. Mauriège, ... D. R. Joanisse in Quality of Life Research
    Article 13 February 2023
  12. Association between genetic polymorphisms and other attributing factors with lipid profiles among statin users: a cross-sectional retrospective study

    Background

    Statins are well known for their efficacy to improve lipid profiles. Their efficacy varies between individuals and can be modified by...

    Amirul Faez Shamsudin, Sarina Sulong, ... Nur Salwani Bakar in Egyptian Journal of Medical Human Genetics
    Article Open access 16 April 2024
  13. The neuropsychology of statin intolerance

    Jennifer G. Robinson in Nature Reviews Cardiology
    Article 06 January 2021
  14. Association Between Vitamin D and Statin-Related Myopathy: A Meta-analysis

    Background

    Myopathy is the most widely reported statin-associated adverse event. Several studies have linked vitamin D deficiency with statin-related...

    Qingtao Hou, Caishuang Pang, Yuqin Chen in American Journal of Cardiovascular Drugs
    Article 23 July 2021
  15. Statin-induced autoimmune myositis: a proposal of an “experience-based” diagnostic algorithm from the analysis of 69 patients

    Statin-induced autoimmune myositis (SIAM) represents a rare clinical entity that can be triggered by prolonged statin treatment. Its pathogenetic...

    Carola Maria Gagliardo, Davide Noto, ... Maurizio Averna in Internal and Emergency Medicine
    Article Open access 05 May 2023
  16. Does high dose statin pretreatment affect global strains in patients undergoing valve replacement

    Purpose

    To study the effect of rosuvastatin 40 mg (initiated 7 days prior to surgery) in patients undergoing valve replacement (VR) for rheumatic...

    Sudesh Prajapathi, Aditya Kapoor, ... Satyendra Tewari in Indian Journal of Thoracic and Cardiovascular Surgery
    Article 22 December 2023
  17. Should a Statin be Given to All Hypertensive Patients?

    Purpose of Review

    To review the milestone trials and recent literature supporting statin therapy for prevention of atherosclerotic cardiovascular...

    Daniel E. McNavish, Charles A. German, Michael D. Shapiro in Current Hypertension Reports
    Article 24 January 2022
  18. Using deep learning-based natural language processing to identify reasons for statin nonuse in patients with atherosclerotic cardiovascular disease

    Background

    Statins conclusively decrease mortality in atherosclerotic cardiovascular disease (ASCVD), the leading cause of death worldwide, and are...

    Ashish Sarraju, Jean Coquet, ... Fatima Rodriguez in Communications Medicine
    Article Open access 15 July 2022
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