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Statin intolerance management: a systematic review
BackgroundStatin intolerance is a key barrier to the effective prevention of atherosclerotic cardiovascular disease (ASCVD). Experts do not agree on...
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Statin Intolerance: an Overview of US and International Guidance
Purpose of ReviewTo review recent international and domestic definitions, considerations, and treatment algorithms for statin intolerance, and...
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A Review of Statin Intolerance: a Focus on Statin-Attributed Muscle Symptoms
Purpose of ReviewTo provide a systematic approach to management of the patient with statin-attributed muscle symptoms.
Recent Findings ... -
SAMSON and the Nocebo Effect: Management of Statin Intolerance
Purpose of ReviewStatins are essential medications in the treatment of atherosclerotic cardiovascular disease; however, remain widely underutilized...
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A mobile health application for patients eligible for statin therapy: app development and qualitative feedback on design and usability
BackgroundCardiovascular disease is the leading cause of death in the United States (US). Despite the well-recognized efficacy of statins, statin...
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Decoding the Intricacies of Statin-Associated Muscle Symptoms
Purpose of ReviewHyperlipidemia is the major cardiovascular morbidity and mortality risk factor. Statins are the first-line treatment for...
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Evaluating Statin Tolerability in Historically Intolerant Patients After Correcting for Subclinical Hypothyroidism and Vitamin D Insufficiency
IntroductionAtherosclerotic cardiovascular disease (ASCVD) is the major cause of morbidity and mortality worldwide. Statins provide primary and...
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The Role of Mitochondria in Statin-Induced Myopathy
Statins represent the primary therapy for combatting hypercholesterolemia and reducing mortality from cardiovascular events. Despite their...
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Bempedoic Acid in the Treatment of Patients with Dyslipidemias and Statin Intolerance
An elevated plasma low-density lipoprotein cholesterol (LDL-C) level is a well-established atherosclerotic cardiovascular disease (ACSVD) risk...
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Statin Intolerance in Clinical Practice
Purpose of ReviewIn our pilot study, we aimed to determine how many patients with the statin intolerance history referred to the specialized center...
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Statin withdrawal and health-related quality of life in a primary cardiovascular prevention cohort
PurposeWhile some work has been done on Health-Related Quality of Life (HRQoL) in statin users, none has focused specifically on statin-associated...
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Association between genetic polymorphisms and other attributing factors with lipid profiles among statin users: a cross-sectional retrospective study
BackgroundStatins are well known for their efficacy to improve lipid profiles. Their efficacy varies between individuals and can be modified by...
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Association Between Vitamin D and Statin-Related Myopathy: A Meta-analysis
BackgroundMyopathy is the most widely reported statin-associated adverse event. Several studies have linked vitamin D deficiency with statin-related...
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Statin-induced autoimmune myositis: a proposal of an “experience-based” diagnostic algorithm from the analysis of 69 patients
Statin-induced autoimmune myositis (SIAM) represents a rare clinical entity that can be triggered by prolonged statin treatment. Its pathogenetic...
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Does high dose statin pretreatment affect global strains in patients undergoing valve replacement
PurposeTo study the effect of rosuvastatin 40 mg (initiated 7 days prior to surgery) in patients undergoing valve replacement (VR) for rheumatic...
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Should a Statin be Given to All Hypertensive Patients?
Purpose of ReviewTo review the milestone trials and recent literature supporting statin therapy for prevention of atherosclerotic cardiovascular...
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Using deep learning-based natural language processing to identify reasons for statin nonuse in patients with atherosclerotic cardiovascular disease
BackgroundStatins conclusively decrease mortality in atherosclerotic cardiovascular disease (ASCVD), the leading cause of death worldwide, and are...