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Current cough and sputum assessed by the cough and sputum assessment-questionnaire (CASA-Q) is associated with quality of life impairment in cystic fibrosis
BackgroundCough and sputum are major symptoms in cystic fibrosis (CF) that contribute to the impairment of quality of life.
MethodsThis prospective...
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Value of sputum Gram stain, sputum culture, and bronchoalveolar lavage fluid Gram stain in predicting single bacterial pathogen among children with community-acquired pneumonia
BackgroundCurrently, the microbial etiology of community-acquired pneumonia in children remains challenging. While Gram stain and sputum culture are...
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The agreement between bronchoalveolar lavage, bronchial wash and sputum culture: a retrospective study
PurposeBronchoalveolar lavage is commonly used in clinical practice for unresolved pneumonia. However, bronchoalveolar lavage is not suitable for all...
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Pooling sputum samples for the Xpert MTB/RIF assay: a practical screening strategy for highly infectious tuberculosis cases
The Xpert MTB/RIF test (Xpert) can help in the accurate screening of tuberculosis, however, its widespread use is limited by its high cost and lack...
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Blood and sputum eosinophilia in COPD exacerbation
BackgroundExacerbations in chronic obstructive pulmonary disease (COPD) are major contributors to worsening lung function, impaired quality of life,...
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Time to sputum culture conversion and its associated factors among drug-resistant tuberculosis patients: a systematic review and meta-analysis
ObjectiveWe aimed to evaluate the sputum culture conversion time of DR-TB patients and its related factors.
MethodsPubMed, The Cochrane Library,...
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Ex-vivo RNA expression analysis of vaccine candidate genes in COPD sputum samples
BackgroundChronic obstructive pulmonary disease (COPD) is a lung disease characterised by airflow-limiting inflammation and mucus production. Acute...
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Comparable detection of nasopharyngeal swabs and induced sputum specimens for viral nucleic acid detection of suspected novel coronavirus (SARS-Cov-2) patients in Fayoum governorate, Egypt
BackgroundThe most commonly utilized samples for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detection using real-time quantitative...
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Highly diverse sputum microbiota correlates with the disease severity in patients with community-acquired pneumonia: a longitudinal cohort study
BackgroundCommunity-acquired pneumonia (CAP) is a common and serious condition that can be caused by a variety of pathogens. However, much remains...
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Transcriptomic responses in the blood and sputum of cigarette smokers compared to e-cigarette vapers
RationaleElectronic (e)-cigarettes are popular among youth and cigarette smokers attempting to quit. Studies to date have focused on the utility of...
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Comparative study of diagnostic efficacy of sputum and bronchoalveolar lavage fluid specimens in community-acquired pneumonia children treated with fiberoptic bronchoscopy
BackgroundCommunity-acquired pneumonia (CAP) is usually diagnosed in children, and the type of respiratory specimen is critical. Differences in...
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Impact of diurnal temperature variations on sputum bacterial detection in hospitalized patients with acute COPD exacerbation: a retrospective study from Fuzhou, China
ObjectiveTo investigate the association between meteorological data three days before admission and the status of sputum pathogens culture in...
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Sputum lipoarabinomannan (LAM) as a biomarker to determine sputum mycobacterial load: exploratory and model-based analyses of integrated data from four cohorts
BackgroundDespite the high global disease burden of tuberculosis (TB), the disease caused by Mycobacterium tuberculosis ( Mtb ) infection, novel...
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Efficacy of three sputum specimens for the diagnosis of Mycobacterium avium complex pulmonary disease
BackgroundIn Mycobacterium avium complex pulmonary disease (MAC-PD), diagnosis requires a positive culture from at least two separate expectorated...
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The effect of azithromycin on sputum inflammatory markers in bronchiectasis
BackgroundLong term macrolide treatment has been found beneficial in bronchiectasis (BE) -pathogical bronchial dilatation- possibly due to a combined...
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Diagnosis of Respiratory Syncytial Virus in Adults Substantially Increases When Adding Sputum, Saliva, and Serology Testing to Nasopharyngeal Swab RT–PCR
IntroductionNearly all existing respiratory syncytial virus (RSV) incidence estimates are based on real-time polymerase chain reaction (RT–PCR)...
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Low human beta-defensin-2 levels in the sputum of COPD patients are associated with the risk of exacerbations
RationaleChronic obstructive pulmonary disease (COPD) is a complicated chronic inflammatory disease. It is important to investigate the...
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Sputum from patients with primary ciliary dyskinesia contains high numbers of dysfunctional neutrophils and inhibits efferocytosis
BackgroundPrimary ciliary dyskinesia (PCD) is a genetic disorder characterized by recurrent airway infection and inflammation. There is no cure for...
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Sputum culture and antibiotic resistance in elderly inpatients with exacerbation of chronic obstructive pulmonary disease at a tertiary geriatric hospital in southern Vietnam
ObjectiveTo determine the rate of positive culture sputum and related factors as well as the microorganism features and antibiotic susceptibility of...
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Outcomes of early fiberoptic bronchoscopic sputum aspiration and lavage after thoracoscopic and laparoscopic esophageal cancer surgery: a randomized clinical trial
BackgroundThis study aims to investigate the outcomes of patients who received early fiberoptic bronchoscopic sputum aspiration and lavage after...
