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Value of sputum Gram stain, sputum culture, and bronchoalveolar lavage fluid Gram stain in predicting single bacterial pathogen among children with community-acquired pneumonia
BackgroundCurrently, the microbial etiology of community-acquired pneumonia in children remains challenging. While Gram stain and sputum culture are...
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Time to sputum culture conversion and its associated factors among drug-resistant tuberculosis patients: a systematic review and meta-analysis
ObjectiveWe aimed to evaluate the sputum culture conversion time of DR-TB patients and its related factors.
MethodsPubMed, The Cochrane Library,...
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The agreement between bronchoalveolar lavage, bronchial wash and sputum culture: a retrospective study
PurposeBronchoalveolar lavage is commonly used in clinical practice for unresolved pneumonia. However, bronchoalveolar lavage is not suitable for all...
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Risk factors for clinical progression in patients with pulmonary Mycobacterium avium complex disease without culture-positive sputum: a single-center, retrospective study
ObjectivesLimited data are available on the progression of pulmonary Mycobacterium avium complex (MAC) disease without culture-positive sputum. The...
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Sputum culture and antibiotic resistance in elderly inpatients with exacerbation of chronic obstructive pulmonary disease at a tertiary geriatric hospital in southern Vietnam
ObjectiveTo determine the rate of positive culture sputum and related factors as well as the microorganism features and antibiotic susceptibility of...
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Methods for handling missing data in serially sampled sputum specimens for mycobacterial culture conversion calculation
BackgroundThe occurrence and timing of mycobacterial culture conversion is used as a proxy for tuberculosis treatment response. When researchers...
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The effects of aerobic exercises compared to conventional chest physiotherapy on pulmonary function, functional capacity, sputum culture, and quality of life in children and adolescents with cystic fibrosis: a study protocol for randomized controlled trial study
BackgroundCystic fibrosis (CF) is an autosomal recessive disorder caused by abnormal function of the chloride ion channels and characterized by...
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Impact of diurnal temperature variations on sputum bacterial detection in hospitalized patients with acute COPD exacerbation: a retrospective study from Fuzhou, China
ObjectiveTo investigate the association between meteorological data three days before admission and the status of sputum pathogens culture in...
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Antimicrobial susceptibility and genoty** of microorganisms isolated from sputum culture of children with cystic fibrosis in an Iranian referral children’s hospital
BackgroundChronic bacterial infections of the airways are present in most patients with cystic fibrosis (CF). Although most pathogens are acquired...
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Efficacy of three sputum specimens for the diagnosis of Mycobacterium avium complex pulmonary disease
BackgroundIn Mycobacterium avium complex pulmonary disease (MAC-PD), diagnosis requires a positive culture from at least two separate expectorated...
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Sputum lipoarabinomannan (LAM) as a biomarker to determine sputum mycobacterial load: exploratory and model-based analyses of integrated data from four cohorts
BackgroundDespite the high global disease burden of tuberculosis (TB), the disease caused by Mycobacterium tuberculosis ( Mtb ) infection, novel...
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Pooling sputum samples for the Xpert MTB/RIF assay: a practical screening strategy for highly infectious tuberculosis cases
The Xpert MTB/RIF test (Xpert) can help in the accurate screening of tuberculosis, however, its widespread use is limited by its high cost and lack...
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Cough and sputum in long COVID are associated with severe acute COVID-19: a Japanese cohort study
BackgroundMultiple prolonged symptoms are observed in patients who recover from acute coronavirus disease 2019 (COVID-19), defined as long COVID....
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Ex-vivo RNA expression analysis of vaccine candidate genes in COPD sputum samples
BackgroundChronic obstructive pulmonary disease (COPD) is a lung disease characterised by airflow-limiting inflammation and mucus production. Acute...
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Prognostic accuracy of time to sputum culture conversion in predicting cure in extensively drug-resistant tuberculosis patients: a multicentre retrospective observational study
BackgroundThere was a lack of information about prognostic accuracy of time to sputum culture conversion (SCC) in forecasting cure among extensively...
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Highly diverse sputum microbiota correlates with the disease severity in patients with community-acquired pneumonia: a longitudinal cohort study
BackgroundCommunity-acquired pneumonia (CAP) is a common and serious condition that can be caused by a variety of pathogens. However, much remains...
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Accurate and affordable detection of rifampicin and isoniazid resistance in Tuberculosis sputum specimens by multiplex PCR-multiple probes melting analysis
BackgroundEscalating cases of multidrug-resistant tuberculosis (MDR-TB) pose a major challenge to global TB control efforts, necessitating innovative...
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Clinical usefulness of sputum culture on the first postoperative day to predict early postoperative pneumonia after esophagectomy for esophageal cancer
BackgroundPostoperative pneumonia is a serious prognostic problem that can appear after esophagectomy in patients with esophageal cancer. The past...
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Comparative study of diagnostic efficacy of sputum and bronchoalveolar lavage fluid specimens in community-acquired pneumonia children treated with fiberoptic bronchoscopy
BackgroundCommunity-acquired pneumonia (CAP) is usually diagnosed in children, and the type of respiratory specimen is critical. Differences in...
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Outcomes of early fiberoptic bronchoscopic sputum aspiration and lavage after thoracoscopic and laparoscopic esophageal cancer surgery: a randomized clinical trial
BackgroundThis study aims to investigate the outcomes of patients who received early fiberoptic bronchoscopic sputum aspiration and lavage after...
