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Relationship between degree of methylation of sperm long interspersed nuclear element-1 (LINE-1) gene and alteration of sperm parameters and age: a meta-regression analysis
IntroductionThe long interspersed nuclear element-1 ( LINE1 ) gene is a retrotransposon whose methylation status appears to play a role in...
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Sperm chromatin structure assay (SCSA®) and flow cytometry-assisted TUNEL assay provide a concordant assessment of sperm DNA fragmentation as a function of age in a large cohort of approximately 10,000 patients
BackgroundSperm DNA integrity is increasingly seen as a critical characteristic determining reproductive success, both in natural reproduction and in...
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In cases with raised sperm DNA fragmentation, can sperm selection by magnetic-activated cell sorting or testicular sperm aspiration help improve reproductive outcomes?
PurposeTo evaluate the efficacy of magnetic-activated cell sorting (MACS) or testicular sperm aspiration (TESA) to improve reproductive outcomes in...
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Sperm chromosomal abnormalities in infertile men with failed intracytoplasmic sperm injection (ICSI)
BackgroundMale infertility is a major health problem with multi-factorial etiology. Intracytoplasmic sperm injection (ICSI) has revolutionized the...
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Cannabidiol impairs sperm quality and function in adult mice
BackgroundConsidering the growing therapeutic use of cannabidiol as well as the presence of cannabinoid receptors in sperm and its possible genotoxic...
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Clinical Utility of Sperm Function Tests in Predicting Male Fertility: A Systematic Review
Routine semen analysis provides considerable information regarding sperm parameters; however, it is not solely adequate to predict male fertility...
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Loss of ACTL7A causes small head sperm by defective acrosome-acroplaxome-manchette complex
BackgroundActin-like 7 A (ACTL7A) is essential for acrosome formation, fertilization and early embryo development. ACTL7A variants cause acrosome...
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Emerging trends in sperm selection: enhancing success rates in assisted reproduction
This comprehensive review explores the evolving landscape of sperm selection techniques within the realm of Assisted Reproductive Technology (ART)....
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Effect of season on the dynamics of cat sperm DNA fragmentation
BackgroundFeline species undergo reproductive seasonality; thus, sperm characteristics, such as DNA integrity, can be affected by the photoperiod....
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Evaluation of in vitro effects of platelet rich plasma on cadmium chloride–treated rat sperm
Cadmium is a heavy metal with wide industrial applications. Humans are exposed to cadmium through different ways. Cadmium demonstrates a low...
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A pilot study of LINE-1 copy number and telomere length with aging in human sperm
PurposeUnlike other cells in the body, in sperm, telomere length (TL) increases with age. TL can regulate nearby genes, and the subtelomeric region...
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Assessing the Impact of the Novel Sperm Selection Technique 'Annexin-V Coated Polystyrene Bead Technique' on Mouse Assisted Reproductive Techniques Outcomes: Preliminary Findings
ICSI is one of the most commonly used techniques to treat infertility. The sperm selection for the procedure is done ‘randomly’ by the embryologist...
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Effects of alcohol use on sperm chromatin structure, a retrospective analysis
BackgroundThe evaluation of the infertile couple is often complex as multiple factors in both the male and female can contribute, including social...
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Effect of Advanced Glycation end Products (AGEs) on Sperm Parameters and Function in C57Bl/6 Mice
This study investigated the deleterious impact of advanced glycation end products (AGEs), commonly present in metabolic disorders like diabetes,...
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Detailed cell-level analysis of sperm nuclear quality among the different hypo-osmotic swelling test (HOST) classes
PurposeWe studied the quality differences between the different hypo-osmotic swelling test (HOST) classes, as measured by criteria of DNA...
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Performing a sperm DNA fragmentation test in addition to semen examination based on the WHO criteria can be a more accurate diagnosis of IVF outcomes
BackgroundWe analyzed the sperm DNA fragmentation index (DFI) and general semen test based on the World Health Organization (WHO) criteria and...
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Micronutrient supplements as antioxidants in improving sperm quality and reducing DNA fragmentation
BackgroundSpermatogenesis and sperm quality may be negatively impacted by an increase in reactive oxygen species. This study investigates the...
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Microfluidic chips as a method for sperm selection improve fertilization rate in couples with fertilization failure
PurposeSperm quality plays a vital role in successful fertilization and pregnancy. Patients with fertilization failure (total failure or...
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Canine sperm motility is associated with telomere shortening and changes in expression of shelterin genes
BackgroundMotion quality is a critical property for essential functions. Several endogenous and exogenous factors are involved in sperm motility....
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Effects of intratesticular injection of hypertonic mannitol and saline on the quality of donkey sperm, indicators of oxidative stress and testicular tissue pathology
ObjectivesThe aim of the present study was to examine donkey sperm quality after intratesticular injection of hypertonic mannitol (HM) and saline...
