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Soluble urokinase plasminogen activator receptor (suPAR) in children with obesity or type 1 diabetes as a marker of endothelial dysfunction: a cross-sectional study
Pediatric obesity and type 1 diabetes mellitus (T1DM) represent two common chronic diseases associated with chronic inflammation, endothelial...
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Soluble urokinase plasminogen activator receptor (suPAR) in bronchoalveolar fluid and blood in critically ill patients—a prospective cohort study
IntroductionSoluble urokinase plasminogen activator receptor (suPAR) is a biologically active protein and increased levels are associated with worse...
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Role of Soluble Urokinase-Type Plasminogen Activator Receptor in Cardiovascular Disease
Purpose of ReviewChronic inflammation is a major contributor to cardiovascular disease (CVD) risk. Soluble urokinase plasminogen activator receptor...
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Soluble urokinase plasminogen activator receptor and cardiotoxicity in doxorubicin-treated breast cancer patients: a prospective exploratory study
BackgroundSoluble urokinase plasminogen activator receptor is an inflammatory biomarker that may prognosticate cardiovascular outcomes. We sought to...
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Soluble urokinase plasminogen activator receptor in vaginally collected amniotic fluid predicting fetal inflammatory response syndrome: a prospective cohort study
BackgroundImproving noninvasive antenatal diagnosis of fetal inflammatory response syndrome (FIRS) can assist in the evaluation of prenatal risk and...
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Soluble urokinase plasminogen activator receptor (suPAR) and glomerular disease in children: a narrative review
BackgroundFocal segmental glomerulosclerosis (FSGS) is a chronic glomerular disease that responds poorly to treatment, with a large proportion of...
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Serum levels of soluble urokinase plasminogen activator receptor in juvenile idiopathic arthritis: a single-center Swedish case-control study
ObjectivesReliable biomarkers in the early stages of idiopathic arthritis (JIA) are scarce and the disease heterogeneity makes it clinically...
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Soluble urokinase plasminogen activator receptor is associated with cardiovascular calcification in peritoneal dialysis patients
BackgroundCardiovascular disease (CVD) is an important cause of morbidity and mortality in peritoneal dialysis (PD) patients. Cardiovascular...
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Exploring low grade inflammation by soluble urokinase plasminogen activator receptor levels in schizophrenia: a sex-dependent association with depressive symptoms
BackgroundThere is evidence of increased low grade inflammation (LGI) in schizophrenia patients. However, the inter-individual variation is large and...
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Soluble urokinase plasminogen activator receptor is associated with short-term mortality and enhanced reactive oxygen species production in acute-on-chronic liver failure
BackgroundAcute-on-chronic liver failure (ACLF) is a comprehensive syndrome characterized by an acute deterioration of liver function and high...
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Soluble urokinase plasminogen activator receptor and lactate as prognostic biomarkers in patients presenting with non-specific chief complaints in the pre-hospital setting – the PRIUS-study
BackgroundEmergency Medical Services (EMS) are faced daily with patients presenting with non-specific chief complaints (NSC). Patients presenting...
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qSOFA combined with suPAR for early risk detection and guidance of antibiotic treatment in the emergency department: a randomized controlled trial
BackgroundSepsis guidelines suggest immediate start of resuscitation for patients with quick Sequential Organ Failure Assessment (qSOFA) 2 or 3....
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Predictive value of suPAR in AKI: a systematic review and meta-analysis
BackgroundSome clinical trials have shown that soluble urokinase-type plasminogen activator receptor (suPAR) has good predictive value for acute...
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The Role of Coagulation in Heart Failure: A Literature Review
Purpose of ReviewThis article summarizes the role of coagulation factors in the pathophysiology of heart failure including D-dimer, fibrinogen and...
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Kinetics of SuPAR hemoadsorption in critical COVID-19 patients on renal replacement therapy
BackgroundSARS-CoV-2 viral infection is associated with a rapid and vigorous systemic inflammatory response syndrome. Soluble urokinase-type...
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Plasma levels of soluble urokinase plasminogen activator receptor (suPAR) and high-sensitivity C-reactive protein after Roux-en-Y gastric bypass or sleeve gastrectomy: a 1-year prospective observational study
PurposeLow-grade inflammation in obesity contributes to the development of cardiovascular disease, diabetes mellitus and cancer, and is associated...
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Irregularities of Coagulation in Hypertension
Purpose of ReviewThis review article summarizes the role of coagulation in the pathogenesis of hypertension. It specifically focuses on significant...
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Association between serum levels of GDF-15, suPAR, PIVKA-II, sdLDL and clinical outcomes in hospitalized COVID-19 patients
To quantify the circulating levels of novel serum biomarkers including GDF-15, PIVKA-II, sdLDL, suPAR, and of CRP in hospitalized COVID-19 patients...
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Prognostic Role of Soluble Urokinase Plasminogen Activator Receptor at the Emergency Department: A Position Paper by the Hellenic Sepsis Study Group
In light of the accumulating evidence on the negative predictive value of soluble urokinase plasminogen activator receptor (suPAR), a group of...
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suPARnostic: an advanced predictive tool for detecting recurrence in renal cell carcinoma
BackgroundPlasma soluble urokinase-type Plasminogen Activator Receptor (suPAR) predicts disease aggressiveness in renal cell carcinoma (ccRCC), but...
