Search
Search Results
-
Safety and Efficacy of Hybrid Cooperative Complexes of Sodium Hyaluronate and Sodium Chondroitin for the Treatment of Patients with Symptomatic Knee Osteoarthritis
IntroductionKnee osteoarthritis (KOA) represents a widespread degenerative disease that causes pain and motor disability. Conservative treatments...
-
Glycosaminoglycan Replacement Therapy with Intravesical Instillations of Combined Hyaluronic Acid and Chondroitin Sulfate in Patients with Recurrent Cystitis, Post-radiation Cystitis and Bladder Pain Syndrome: A Narrative Review
Defects in the glycosaminoglycan layer (GAG) of the bladder mucosa have been identified as a significant contributor to the pathogenesis and clinical...
-
The efficacy and safety of intravesical chondroitin sulphate solution in recurrent urinary tract infections
BackgroundUrinary tract infections are among the most common indications for antibiotic therapy. The emergence of resistant uropathogens indicates...
-
Single-Dose Intra-Articular Administration of a Hybrid Cooperative Complex of Sodium Hyaluronate and Sodium Chondroitin in the Treatment of Symptomatic Hip Osteoarthritis: A Single-Arm, Open-Label, Pilot Study
IntroductionIntra-articular (i.a.) hyaluronic acid is an accepted conservative therapy for knee osteoarthritis (OA). This study evaluated the safety...
-
Effects of oral treatment with chondroitin sulfate and glucosamine in an experimental model of metacarpophalangeal osteoarthritis in horses
BackgroundCombined chondroitin sulfate (CS) and glucosamine (GlcN) has been widely used in oral formulations to prevent and treat osteoarthritis. CS...
-
Chondroitin Sulfate Enhances Proliferation and Migration via Inducing β-Catenin and Intracellular ROS as Well as Suppressing Metalloproteinases through Akt/NF-ϰB Pathway Inhibition in Human Chondrocytes
BackgroundChondroitin sulfate (CS) is found in humans’ cartilage, bone, cornea, skin, and arterial wall. It consists of the foundation substance in...
-
Suprachoroidal triamcinolone versus posterior subtenon triamcinolone either alone or formulated in the management of diabetic macular edema
PurposeThis study aims to compare posterior subtenon triamcinolone acetonide injection either formulated or alone versus suprachoroidal triamcinolone...
-
Nerve growth factor-chondroitin sulfate/hydroxyapatite-coating composite implant induces early osseointegration and nerve regeneration of peri-implant tissues in Beagle dogs
BackgroundOsseointegration is the premise of the chewing function of dental implant. Nerve growth factor (NGF), as a neurotrophic factor, can induce...
-
A Review of the Clinical Effectiveness and Safety of Hybrid Cooperative Complexes in Intra-articular Viscosupplementation
Viscosupplementation by intra-articular (i.a.) injection of the non-sulfated glycosaminoglycan (GAG) hyaluronic acid (HA) is a conservative therapy...
-
Clinical study of warm needling moxibustion plus intra-articular injection of sodium hyaluronate for chondromalacia patellae
ObjectiveTo observe the therapeutic efficacy of warm needling moxibustion plus intra-articular injection of sodium hyaluronate in treating...
-
The comparison of curcuminoid formulations or its combination with conventional therapies versus conventional therapies alone for knee osteoarthritis
BackgroundPresently, curcuminoid formulations or its combination with conventional therapies has been used for the treatment of knee osteoarthritis...
-
Outcomes of intravesical chondroitin-sulfate and combined hyaluronic-acid/chondroitin-sulfate therapy on female sexual function in bladder pain syndrome
Introduction and hypothesisOur aim was to determine the efficacy of intravesical chondroitin sulfate (CS) and combined hyaluronic acid/chondroitin...
-
Intravesical instillation of high molecular weight sodium hyaluronate in radiation-induced cystitis: a prospective pilot study
PurposeTo assess the efficacy and safety of intravesical instillation of high molecular weight sodium hyaluronate (HMW-HA) for the treatment of...
-
Can sodium MRI be used as a method for map** of cartilage stiffness?
ObjectiveSodium concentration is responsible for (at least part of) the stiffness of articular cartilage due to the osmotic pressure it generates....
-
Comparative Analyses of Pharmaceuticals or Food Supplements Containing Chondroitin Sulfate: Are Their Bioactivities Equivalent?
IntroductionOral supplementation of chondroitin sulfate (CS) and glucosamine (GlcN), symptomatic slow-acting molecules, is recommended by European...
-
Increased migratory activity and cartilage regeneration by superficial-zone chondrocytes in enzymatically treated cartilage explants
BackgroundLimited chondrocyte migration and impaired cartilage-to-cartilage healing is a barrier in cartilage regenerative therapy. Collagenase...
-
A nutraceutical formulation combined with sclerofoam-assisted laser treatment ameliorates chronic venous insufficiency
Chronic venous insufficiency has a high impact on the healthcare system due to its high incidence worldwide. We performed a study in 30 women with...
-
Efficacy and safety comparison of pharmacotherapies for interstitial cystitis and bladder pain syndrome: a systematic review and Bayesian network meta-analysis
Introduction and hypothesisThe objective was to compare the clinical efficacy and safety of pharmacological interventions for interstitial cystitis...
