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Sleep is Essential for Mental Health: Potential Role of Slow Oscillations
Purpose of ReviewSleep is a physiological process characterized by a crucial interaction between behavioural and neurobiological aspects, thereby...
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Neuroligin-2 shapes individual slow waves during slow-wave sleep and the response to sleep deprivation in mice
BackgroundSleep disturbances are a common comorbidity to most neurodevelopmental disorders and tend to worsen disease symptomatology. It is thus...
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Electrophysiological Mechanisms of Memory Consolidation in Human Non-rapid Eye Movement Sleep
Purpose of ReviewPioneering work in rodents has shown that the reactivation of recently acquired memories during sleep is a key mechanism underlying...
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Abnormal patterns of sleep and waking behaviors are accompanied by neocortical oscillation disturbances in an Ank3 mouse model of epilepsy-bipolar disorder comorbidity
ANK3 is a leading bipolar disorder (BD) candidate gene in humans and provides a unique opportunity for studying epilepsy-BD comorbidity. Previous...
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Role of sleep in neurodegeneration: the consensus report of the 5th Think Tank World Sleep Forum
Sleep abnormalities may represent an independent risk factor for neurodegeneration. An international expert group convened in 2021 to discuss the...
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Psilocin acutely alters sleep-wake architecture and cortical brain activity in laboratory mice
Serotonergic psychedelic drugs, such as psilocin (4-hydroxy-N,N-dimethyltryptamine), profoundly alter the quality of consciousness through mechanisms...
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Sleep disturbance in Angelman syndrome patients
Angelman syndrome (AS) is a neurodevelopmental disorder caused by abnormal expression of the maternal ubiquitin protein ligase E3A gene ( UBE3A ). As...
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The Impact of Vestibular Stimulation on Sleep and Respiration in Humans
Purpose of ReviewThe vestibular system plays a role in both sleep and circadian rhythm regulation. Therefore, it has become a target for those...
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The Utility of Non-invasive Brain Stimulation in Relieving Insomnia Symptoms and Sleep Disturbances Across Different Sleep Disorders: a Topical Review
Purpose of ReviewThe present topical review aims to summarize the literature to give an overview of the clinical utility of non-invasive brain...
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A Thalamocortical Perspective on Sleep Spindle Alterations in Neurodevelopmental Disorders
Purpose of ReviewNeurodevelopmental disorders are a group of conditions that affect the development and function of the nervous system, typically...
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Sleep-Dependent Memory Consolidation in Developmental Disabilities: Cognitive and Neural Factors Driving Heterogeneity Across Diagnoses
Purpose of ReviewSleep plays an important role in the long-term consolidation of memories across development. The current review examines...
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Effects of Mood Stabilizers on Sleep and Circadian Rhythms: A Systematic Review
Purpose of ReviewMood disorders tend to be recurrent, chronic, and disabling, caused by a complex interplay of factors. Within this context, sleep,...
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Generalized sleep decoding with basal ganglia signals in multiple movement disorders
Sleep disturbances profoundly affect the quality of life in individuals with neurological disorders. Closed-loop deep brain stimulation (DBS) holds...
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The GABAA receptor modulator zolpidem augments hippocampal-prefrontal coupling during non-REM sleep
Benzodiazepines and ‘Z-drugs’ (including zolpidem and zopiclone) are GABA A receptor (GABA A R) positive modulators commonly prescribed as hypnotics to...
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NREM sleep as a novel protective cognitive reserve factor in the face of Alzheimer's disease pathology
BackgroundAlzheimer’s disease (AD) pathology impairs cognitive function. Yet some individuals with high amounts of AD pathology suffer marked memory...
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The Influence of Sleep Disturbance on Chronic Pain
Purpose of ReviewThe purpose of this review is to present an overview of common sleep disturbance pathologies and their impact on chronic pain, while...
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Targeting sleep and the circadian system as a novel treatment strategy for Parkinson’s disease
There is a growing appreciation of the wide range of sleep–wake disturbances that occur frequently in Parkinson’s disease. These are known to be...
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Remote evaluation of sleep to enhance understanding of early dementia due to Alzheimer’s Disease (RESTED-AD): an observational cohort study protocol
BackgroundSleep and circadian rhythm disorders are well recognised in both AD (Alzheimer’s Disease) dementia and MCI-AD (Mild Cognitive Impairment...
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Kynurenine aminotransferase II inhibition promotes sleep and rescues impairments induced by neurodevelopmental insult
Dysregulated sleep is commonly reported in individuals with neuropsychiatric disorders, including schizophrenia (SCZ) and bipolar disorder (BPD)....
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Modulation of Slow-Wave Sleep: Implications for Psychiatry
Purpose of ReviewThe objectives of this review are to examine and integrate existing empirical evidence regarding the impact of slow-wave sleep (SWS)...