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Effect of blastocyst shrinkage on assisted reproductive outcomes: a retrospective cohort study describing a new morphological evaluation of blastocyst pre-vitrification and post-warming
BackgroundThe failure of frozen-thawed blastocysts to re-expand adequately within a few hours after warming has been reported to have a negative...
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Assessment of mesh shrinkage using fibroblast-populated collagen matrices: a proof of concept for in vitro hernia mesh testing
PurposeThis study uses free-floating contractile fibroblast-populated collagen matrices (FPCMs) to test the shrinkage of different hernia mesh...
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Applications of Bayesian shrinkage prior models in clinical research with categorical responses
BackgroundPrediction and classification algorithms are commonly used in clinical research for identifying patients susceptible to clinical conditions...
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Early tumor shrinkage and depth of response in patients with metastatic esophageal cancer treated with 2-weekly docetaxel combined with cisplatin plus fluorouracil: an exploratory analysis of the JCOG0807
BackgroundWe herein investigated the association between early tumor shrinkage (ETS) and depth of response (DpR) and clinical outcomes in patients...
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The prognostic role of early tumor shrinkage in patients with hepatocellular carcinoma undergoing immunotherapy
BackgroundEarly tumor shrinkage (ETS) has been identified as a promising imaging biomarker for patients undergoing immunotherapy for several cancer...
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Morphological response and tumor shrinkage as predictive factors in metastatic colorectal cancer treated with first-line capecitabine, oxaliplatin, and bevacizumab
BackgroundMorphologic response (MR) is a novel chemotherapeutic efficacy predictor of solid tumors, especially those treated with anti-vascular...
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An adaptive gBOIN design with shrinkage boundaries for phase I dose-finding trials
BackgroundWith the emergence of molecularly targeted agents and immunotherapies, the landscape of phase I trials in oncology has been changed. Though...
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Shrinkage estimation of long-term water ingestion rates
BackgroundWater consumption is a necessity for human life, though it also presents an opportunity for exposure to harmful chemicals and toxins. In...
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Prognostic significance of initial tumor shrinkage in patients with stage III non-small cell lung cancer treated with durvalumab following chemoradiotherapy
BackgroundBaseline tumor size (BTS) is one of the prognostic factors of advanced non-small cell lung cancer (NSCLC) treated with immunotherapy....
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Vestibular schwannomas with spontaneous shrinkage: about 35 cases
PurposesThe first aim is to describe the epidemiological, clinical, and radiological characteristics of regressive vestibular schwannomas (VS), based...
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Shrinkage of a pituitary metastasis of melanoma induced by pembrolizumab: a case report
BackgroundPituitary metastases are rare, often deriving from lung or breast cancer owing to the upper vena cava proximity. Pituitary metastases can...
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Shrinkage of specimens after CO2 laser cordectomy: an objective intraoperative evaluation
PurposeThe margin status after CO 2 laser cordectomy for glottic carcinoma may influence prognosis. There are no studies assessing the possible bias...
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Early tumor shrinkage and response assessment according to mRECIST predict overall survival in hepatocellular carcinoma patients under sorafenib
BackgroundThe aim of this study was to explore the relationship between follow-up imaging characteristics and overall survival (OS) in advanced...
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Assessing prognostic value of early tumor shrinkage and depth of response in first-line therapy for patients with advanced unresectable pancreatic cancer
BackgroundThe prognostic potential of early tumor shrinkage (ETS) and depth of response (DpR) in pancreatic cancer (PC) is unclear. Here, we...
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The impact of early tumor shrinkage on conversion surgery and the survival in patients with unresectable locally advanced pancreatic cancer
PurposesOwing to recent advances in induction chemo(radio)therapy, patients with unresectable locally advanced pancreatic ductal adenocarcinoma...
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Optimizing the tumor shrinkage threshold for evaluating immunotherapy efficacy for advanced non-small-cell lung cancer
PurposeThe rise of immune checkpoint inhibitors (ICIs) in recent years has coincided with unusual clinical response patterns. Modification of the sum...
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Plumbagin binds to epidermal growth factor receptor and mitigate the effects of epidermal growth factor micro-environment in PANC-1 cells
A sustained increase in the mortality of pancreatic cancer (PC) and sudden metastasis-related mortality is a cause for concern. Aberrant expression...
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TFRC, associated with hypoxia and immune, is a prognostic factor and potential therapeutic target for bladder cancer
BackgroundBladder cancer is a common malignancy of the urinary system, and the survival rate and recurrence rate of patients with muscular aggressive...
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The interplay between polygenic score for tumor necrosis factor-α, brain structural connectivity, and processing speed in major depression
Reduced processing speed is a core deficit in major depressive disorder (MDD) and has been linked to altered structural brain network connectivity....
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Risk factor analysis and a new prediction model of venous thromboembolism after pancreaticoduodenectomy
AimThe present study aimed to identify risk factors for venous thromboembolism (VTE) after pancreaticoduodenectomy (PD) and to develop and internally...
