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Shenmai Injection Improves Hypertensive Heart Failure by Inhibiting Myocardial Fibrosis via TGF-β 1/Smad Pathway Regulation
ObjectiveTo study effects of Shenmai Injection on hypertensive heart failure and its mechanism for inhibiting myocardial fibrosis.
Methods ... -
Shenmai Injection Attenuates Myocardial Ischemia/Reperfusion Injury by Targeting Nrf2/GPX4 Signalling-Mediated Ferroptosis
ObjectiveTo examine the effect of Shenmai Injection (SMJ) on ferroptosis during myocardial ischemia reperfusion (I/R) injury in rats and the...
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Carbohydrates and ginsenosides in shenmai injection jointly improve hematopoietic function during chemotherapy-induced myelosuppression in mice
BackgroundShenmai injection (SMI), a traditional Chinese medicine (TCM) injection prepared from Red ginseng and Ophiopogon japonicus , is widely used...
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Effect of Shenmai Injection on Long-Term Prognosis of Patients with Chronic Heart Failure: A Multicenter, Large Sample Capacity, Long-Term Follow-Up Retrospective Cohort Study
ObjectiveTo explore the effect of Shenmai Injection (SMI) on the long-term prognosis of patients with chronic heart failure (CHF).
Methods ... -
A systematic review and meta-analysis on sodium tanshinone IIA sulfonate injection for the adjunctive therapy of pulmonary heart disease
AimsSodium tanshinone IIA sulfonate (STS) injection has been widely used as adjunctive therapy for pulmonary heart disease (PHD) in China....
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Effects of Tanreqing Injection on ICU Mortality among ICU Patients Receiving Mechanical Ventilation: Time-Dependent Cox Regression Analysis of A Large Registry
ObjectiveTo assess whether the use of Tanreqing (TRQ) Injection could show improvements in time to extubation, intensive care unit (ICU) mortality,...
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Protective effect of Shenmai injection on doxorubicin-induced cardiotoxicity via regulation of inflammatory mediators
BackgroundDoxorubicin (DOX) is a chemotherapy drug for malignant tumors. The clinical application of DOX is limited due to its dosage relative...
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Investigation of cardiovascular protective effect of Shenmai injection by network pharmacology and pharmacological evaluation
BackgroundShenmai injection (SMI) has been used in the treatment of cardiovascular disease (CVD), such as heart failure, myocardial ischemia and...
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Efficacy and safety of traditional Chinese medicine for cancer-related fatigue: a systematic literature review of randomized controlled trials
BackgroundCancer-related fatigue (CRF) is an extremely common and long-term condition that affects the physical and mental health of oncology...
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Pseudo-allergic reactions induced by Chinese medicine injections: a review
Traditional Chinese medicine injections (TCMIs) is a new dosage form of Chinese medicine, which plays a unique role in rescuing patients with...
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Shenmai injection for the treatment of cancer-related fatigue in advanced non-small cell lung cancer patients undergoing chemotherapy: study protocol for a randomized controlled trial
BackgroundCancer-related fatigue (CRF) is the most common symptom in patients with advanced non-small cell lung cancer (NSCLC) undergoing treatment...
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Shengmai San for Treatment of Cardiotoxicity from Anthracyclines: A Systematic Review and Meta-Analysis
ObjectiveTo systematically evaluate the efficacy of Shengmai San in patients with cardiotoxicity of anthracyclines.
MethodsRandomized controlled...
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Effect of Shenmai injection on cognitive function after cardiopulmonary bypass in cardiac surgical patients: a randomized controlled trial
BackgroundPostoperative cognitive dysfunction (POCD) is a common complication after cardiac surgery that influences the clinical outcomes and quality...
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Which Is Safer, Chinese Medicine or Western Medicine? Comparative Analysis Based on Chinese Spontaneous Reporting Database
ObjectiveTo compare the safety differences between Chinese medicine (CM) and Western medicine (WM) based on Chinese Spontaneous Reporting Database...
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Impact of capitation prepayment on the medical expenses and health service utilization of patients with coronary heart disease: a community policy intervention program in a county in China
BackgroundMedical costs have been rising rapidly in recent years, and China is controlling medical costs from the perspective of health insurance...
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Mitochondrial Dynamin-Related Protein Drp1: a New Player in Cardio-oncology
Purpose of ReviewThis study is aimed at reviewing the recent progress in Drp1 inhibition as a novel approach for reducing doxorubicin-induced...
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Pharmacological Effects of Botanical Drugs on Myocardial Metabolism in Chronic Heart Failure
Although there have been significant advances in the treatment of heart failure in recent years, chronic heart failure remains a leading cause of...
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A review on traditional Chinese medicine natural products and acupuncture intervention for Alzheimer’s disease based on the neuroinflammatory
Alzheimer’s disease (AD) is a neurodegenerative disease with insidious onset and progressive development. It is clinically characterized by cognitive...
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Global metabolomic and lipidomic analysis reveals the potential mechanisms of hemolysis effect of Ophiopogonin D and Ophiopogonin D' in vivo
BackgroundOPD and OPD' are the two main active components of Ophiopogon japonicas in Shenmai injection (SMI). Being isomers of each other, they are...
