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Essential tremor is associated with reduced serum ceruloplasmin levels
BackgroundEssential tremor (ET), a prevalent movement disorder, has an elusive pathogenesis. A reduction in ceruloplasmin (Cp) levels can be found in...
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Assessment of the diagnostic value of serum ceruloplasmin for Wilson’s disease in children
BackgroundSerum ceruloplasmin is one of the major diagnostic parameters for Wilson’s disease (WD). Age and gender difference of serum ceruloplasmin...
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Ceruloplasmin regulating fibrosis in orbital fibroblasts provides a novel therapeutic target for Graves’ orbitopathy
PurposeIn diagnosing the pathogenesis of Graves’ orbitopathy (GO), there is a growing interest in fibrosis generated by orbital fibroblasts (OFs);...
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Analysis of serum peptidome profiles of non-metastatic and metastatic feline mammary carcinoma using liquid chromatography-tandem mass spectrometry
BackgroundFeline mammary carcinoma (FMC) is a common aggressive and highly metastatic cancer affecting female cats. Early detection is essential for...
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Diagnosing aceruloplasminemia: navigating through red herrings
A 58-year-old female was found to have hyperferritinemia (Serum ferritin:1683 ng/mL) during work-up for mild normocytic anemia. Transferrin...
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Short-term effects of roxadustat on serum copper and iron changes in a peritoneal dialysis patient
Dysregulation in total body copper causes severe complications and excess copper can be toxic. Divalent metal transporter 1 , duodenal cytochrome B ,...
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Occurrence of Monoclonal Band in Alpha Region on Serum Electrophoresis in Multiple Myeloma: A Diagnostic Conundrum
The presence of an M-band in serum and/or urine electrophoresis is a crucial diagnostic indicator for multiple myeloma and other plasma cell...
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Serum protein capillary electrophoretic pattern during lactation period in camels (Camelus dromedarius)
Lactation is a physiological state that has been shown to modify protein metabolism in camels. Few data are available concerning the changes in...
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Association between Serum Ferritin Levels and Metabolic-associated Fatty Liver Disease in Adults: a Cross-sectional Study Based on the NHANES
ObjectiveFerritin, initially acting as an iron-storage protein, was found to be associated with metabolic diseases. Our study was designed to...
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Copper deficiency anemia due to zinc supplementation in a chronic hemodialysis patient
Zinc deficiency causes dysgeusia and dermatitis as well as anemia. As approximately half of dialysis patients have zinc deficiency, zinc...
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Serum levels of anti-inflammatory/proinflammatory adipocytokines, and copper levels in overweight and obese women in an adult Mexican population
BackgroundAn imbalance between adipokines and micronutrient concentrations, such as those of copper (Cu), has been linked to dysregulation of energy...
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Brain and the whole-body bone imaging appearances in Menkes disease: a case report and literature review
BackgroundMenkes disease (MD) is a rare, inherited, multisystemic copper metabolism disorder. Classical Menkes disease is characterized by low serum...
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Serum Copper-to-Zinc Ratio and Risk of Chronic Obstructive Pulmonary Disease: A Cohort Study
PurposeSerum copper (Cu), zinc (Zn), and Cu/Zn-ratio have emerged as ageing-related biomarkers. We sought to assess the association between...
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Association between serum copper, zinc, and selenium concentrations and depressive symptoms in the US adult population, NHANES (2011–2016)
BackgroundEvidence suggests that alterations in serum trace element concentrations are closely associated with mental illness. However, studies on...
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New mutation of the ceruloplasmin gene in the case of a neurologically asymptomatic patient with microcytic anaemia, obesity and supposed Wilson’s disease
BackgroundAceruloplasminaemia is a very rare autosomal recessive disorder caused by a mutation in the ceruloplasmin gene, which is clinically...
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Urinary levels of ceruloplasmin and monocyte chemoattractant protein-1 correlate with extra-capillary proliferation and chronic damage in patients with lupus nephritis
Background and aimThere are few studies of urinary biomarkers and histopathologic features in lupus nephritis (LN). The aim was to analyze the...
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Alteration of circulating redox balance in coronavirus disease-19-induced acute respiratory distress syndrome
BackgroundMechanisms underpinning ARDS induced by COVID-19 are mostly immune-mediated, but need to be completely clarified. This study aimed to...
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Systemic lupus erythematosus combined with Wilson’s disease: a case report and literature review
BackgroundSystemic lupus erythematosus (SLE) and Wilson’s disease (WD) are both systemic diseases that can affect multiple organs in the body. The...
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Metal-on-metal metaphyseal and ceramic-on-ceramic femoral neck arthroplasty: the impact on clinical results, oxidative stress and concentration of metal ions in serum and blood
PurposeGrowing number of hip arthroplasty in Poland performed with the use of metaphyseal stems results from the decreasing age of patients qualified...