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The Sequential Organ Failure Assessment (SOFA) Score: has the time come for an update?
The Sequential Organ Failure Assessment (SOFA) score was developed more than 25 years ago to provide a simple method of assessing and monitoring...
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Prognostic evaluation of quick sequential organ failure assessment score in ICU patients with sepsis across different income settings
BackgroundThere is conflicting evidence on association between quick sequential organ failure assessment (qSOFA) and sepsis mortality in ICU...
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Evaluation of Quick Sequential Organ Failure Assessment in Addition to Lactic Acid Levels in Predicting Mortality in Surgical Patients with Complicated Intra-Abdominal Infections
Early prognostic evaluation and appropriate treatment of patients with complicated intra-abdominal infection (cIAI) are crucial for the final...
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Persistent high sepsis-induced coagulopathy and sequential organ failure assessment scores can predict the 28-day mortality of patients with sepsis: A prospective study
BackgroundThe performance of the sepsis-induced coagulopathy (SIC) and sequential organ failure assessment (SOFA) scores in predicting the prognoses...
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A modified Sequential Organ Failure Assessment score for dengue: development, evaluation and proposal for use in clinical trials
BackgroundDengue is a neglected tropical disease, for which no therapeutic agents have shown clinical efficacy to date. Clinical trials have used...
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Association between the intraoperative fluid balance during cardiac surgery and postoperative sequential organ failure assessment score: a post hoc analysis of the BROTHER study, a retrospective multicenter cohort study
Although intraoperative intravenous fluids are commonly administered to reverse intraoperative hypotension during cardiac surgery, the appropriate...
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Neonatal Sequential Organ Failure Assessment as a late-onset sepsis mortality predictor in very low birth weight newborns: a Brazilian cohort study
Death is a frequent occurrence in late-onset neonatal sepsis (LOS). We aimed to evaluate if the Neonatal Sequential Organ Failure Assessment ( nSOFA)...
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Facial appearance associates with longitudinal multi-organ failure: an ICU cohort study
BackgroundFacial appearance, whether consciously or subconsciously assessed, may affect clinical assessment and treatment strategies in the Intensive...
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Impact of therapeutic plasmapheresis on the duration of organ failure in patients with hypertriglyceridemia-associated acute pancreatitis
BackgroundPlasmapheresis is widely used for severe hypertriglyceridemia-associated acute pancreatitis (HTG-AP) to remove excessive triglycerides from...
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Association between left ventricular systolic function parameters and myocardial injury, organ failure and mortality in patients with septic shock
BackgroundLeft ventricular ejection fraction (LVEF) is inconsistently associated with poor outcomes in patients with sepsis. Newer parameters such as...
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Vitamin C as a treatment for organ failure in sepsis
Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection, with a high morbidity and mortality...
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Does Ileus Represent the Forgotten End Organ Failure in Critical Illness?
Purpose of ReviewThis review evaluates the current literature on ileus, impaired gastrointestinal transit (IGT), and acute gastrointestinal injury...
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Outcomes in participants with ventilated nosocomial pneumonia and organ failure treated with ceftolozane/tazobactam versus meropenem: a subset analysis of the phase 3, randomized, controlled ASPECT-NP trial
BackgroundThe pivotal ASPECT-NP trial showed ceftolozane/tazobactam was non-inferior to meropenem for the treatment of ventilated...
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Sonometric assessment of cough predicts extubation failure: SonoWean—a proof-of-concept study
BackgroundExtubation failure is associated with increased mortality. Cough ineffectiveness may be associated with extubation failure, but its...
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Circulating neutrophil extracellular trap (NET)-forming ‘rogue’ neutrophil subset, immunotype [DEspR + CD11b +], mediate multi-organ failure in COVID-19—an observational study
BackgroundCumulative research show association of neutrophils and neutrophil extracellular traps (NETs) with poor outcomes in severe COVID-19....
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Sequential Organ Failure Assessment (SOFA) and 90-day mortality in patients with kidney transplant status at first ICU admission: a cohort study of 428 patients
PurposeWe investigated the prognostic accuracy of scores of SOFA for 90-day mortality in patients with kidney transplant status identified from the...
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Bacteraemia and quick Sepsis Related Organ Failure Assessment (qSOFA) are independent risk factors for long-term mortality in very elderly patients with suspected infection: retrospective cohort study
BackgroundIn older adult patients, bloodstream infections cause significant mortality. However, data on long-term prognosis in very elderly patients...
