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Molecular hydrogen attenuates sepsis-induced cardiomyopathy in mice by promoting autophagy
BackgroundApproximately 40 to 60% of patients with sepsis develop sepsis-induced cardiomyopathy (SIC), which is associated with a substantial...
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Therapeutic Strategies Targeting Mitochondrial Dysfunction in Sepsis-induced Cardiomyopathy
Sepsis is an increasingly worldwide problem; it is currently regarded as a complex life-threatening dysfunction of one or more organs as a result of...
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Association of sepsis-induced cardiomyopathy and mortality: a systematic review and meta-analysis
BackgroundThe implication of sepsis-induced cardiomyopathy (SIC) to prognosis is controversial, and its association with mortality at different...
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Pathophysiology of sepsis-induced cardiomyopathy
Sepsis is the life-threatening organ dysfunction caused by a dysregulated host response to infection and is the leading cause of death in intensive...
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Feasibility and discriminatory value of tissue motion annular displacement in sepsis-induced cardiomyopathy: a single-center retrospective observational study
BackgroundThere is no formal diagnostic criterion for sepsis-induced cardiomyopathy (SICM), but left ventricular ejection fraction (LVEF) < 50% was...
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Pseudo-Wellens syndrome from sepsis-induced cardiomyopathy: a case report and review of the literature
BackgroundPseudo-Wellens syndrome is a rare entity characterized by the presence of electrocardiogram (ECG) changes of Wellens syndrome but without...
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Therapeutic S100A8/A9 blockade inhibits myocardial and systemic inflammation and mitigates sepsis-induced myocardial dysfunction
Background and AimsThe triggering factors of sepsis-induced myocardial dysfunction (SIMD) are poorly understood and are not addressed by current...
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MiR-31-5p alleviates septic cardiomyopathy by targeting BAP1 to inhibit SLC7A11 deubiquitination and ferroptosis
Septic cardiomyopathy is one of the most severe and common complications in patients with sepsis and poses a great threat to their prognosis....
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The clinical effectiveness of sivelestat in treating sepsis patients with both acute respiratory distress syndrome and septic cardiomyopathy
BackgroundWe aimed to assess the efficacy of the neutrophil elastase inhibitor, sivelestat, in the treatment of sepsis-induced acute respiratory...
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**nyang tablet ameliorates sepsis-induced myocardial dysfunction by regulating Beclin-1 to mediate macrophage autophagy and M2 polarization through LncSICRNT1 targeting E3 ubiquitin ligase TRAF6
Objective**nyang Tablet (XYT) has emerged as a potential intervention to counter sepsis-induced myocardial dysfunction (SMID) by influencing...
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Predictors and nomogram of in-hospital mortality in sepsis-induced myocardial injury: a retrospective cohort study
BackgroundSepsis-induced myocardial injury (SIMI) is a common organ dysfunction and is associated with higher mortality in patients with sepsis. We...
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Therapeutic Approaches Targeting Ferroptosis in Cardiomyopathy
The term cardiomyopathy refers to a group of heart diseases that cause severe heart failure over time. Cardiomyopathies have been proven to be...
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Cytosolic mtDNA–cGAS–STING axis contributes to sepsis-induced acute kidney injury via activating the NLRP3 inflammasome
BackgroundNLRP3 inflammasome activation is significantly associated with sepsis-induced acute kidney injury (S-AKI). Cytosolic DNA derived from...
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Sepsis-Induced Cardiomyopathy: a Comprehensive Review
Purpose of ReviewTo briefly review epidemiology and pathophysiology of SICM and provide a more extensive review of the data on diagnostic and...
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miR-22 alleviates sepsis-induced acute kidney injury via targeting the HMGB1/TLR4/NF-κB signaling pathway
BackgroundAcute kidney injury (AKI) is a severe complication of sepsis, and is strongly correlated with MicroRNAs (miRNAs). However, the mechanism of...
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Protective Role of lncRNA TTN-AS1 in Sepsis-Induced Myocardial Injury Via miR-29a/E2F2 Axis
ObjectiveApproximately 50% of patients with sepsis encounter myocardial injury. The mortality of septic patients with cardiac dysfunction (approx....
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Unusual cerebral intraventricular hemorrhage and cardiomyopathy related to congenital cytomegalovirus from non-primary maternal infection: a case report
BackgroundCongenital cytomegalovirus (cCMV) infection, resulting from non-primary maternal infection or reactivation during pregnancy, can cause...
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Irisin attenuates type 1 diabetic cardiomyopathy by anti-ferroptosis via SIRT1-mediated deacetylation of p53
BackgroundDiabetic cardiomyopathy (DCM) is a serious complication in patients with type 1 diabetes mellitus (T1DM), which still lacks adequate...
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Moderate exercise-induced dynamics on key sepsis-associated signaling pathways in the liver
BackgroundThere is a clear relationship between quantitative measures of fitness (e.g., VO 2 max) and outcomes after surgical procedures. Whether or...
