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Clinical characteristics and impact of comorbidities on the prognosis of senile epilepsy in Southwest China: a retrospective cohort study
BackgroundSenile epilepsy and its comorbidities pose a tremendous burden on patients and the society. This study was aimed to investigate the...
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Identification of common core ion channel genes in epilepsy and Alzheimer’s disease
BackgroundAlthough available literature indicates that the incidence of dementia in the epilepsy population and the risk of seizures in the...
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Semiology of epileptic seizures in old age and the differential diagnosis – English Version
Epileptic seizures in people older than 60 years cause problems in the diagnosis and assignment, especially if the diagnosis of epilepsy has not yet...
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Classification of Osteoporosis
Osteoporosis is defined by low bone quality, strength and increased fracture risk. Primary and secondary osteoporosis are the two forms of...
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Recent diagnostic techniques for the detection of Alzheimer’s disease: a short review
Alzheimer’s disease (AD) is a neurological condition that affects millions of individuals around the world and for which there are few effective...
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Astrocytes in human central nervous system diseases: a frontier for new therapies
Astroglia are a broad class of neural parenchymal cells primarily dedicated to homoeostasis and defence of the central nervous system (CNS)....
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Seizures provoked by over-the-counter cough and cold medications in an elderly patient: a case report
BackgroundSeizures are common neurological emergencies in the elderly that are frequently provoked. Geriatrics have higher rates of neurological...
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Brain Aging
AbstractBrain aging is part of the aging of the whole body, largely determining the success of general aging and the quality of life of an older...
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Antiseizure Drugs and Movement Disorders
The relationship between antiseizure drugs and movement disorders is complex and not adequately reviewed so far. Antiseizure drugs as a treatment for...
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Causal influences of neuropsychiatric disorders on Alzheimer’s disease
Previous studies have observed a significant comorbidity between Alzheimer’s disease (AD) and some other neuropsychiatric disorders. However, the...
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Cannabis and pathologies in dogs and cats: first survey of phytocannabinoid use in veterinary medicine in Argentina
BackgroundIn animals, the endocannabinoid system regulates multiple physiological functions. Like humans, animals respond to preparations containing...
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Clinical impact of amyloid PET using 18F-florbetapir in patients with cognitive impairment and suspected Alzheimer’s disease: a multicenter study
ObjectiveAmyloid positron emission tomography (PET) can reliably detect senile plaques and fluorinated ligands are approved for clinical use....
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Circular RNAs: Diagnostic and Therapeutic Perspectives in CNS Diseases
Circular RNAs (circRNAs) are a class of regulatory non-coding RNAs characterized by the presence of covalently closed ends. A growing body of...
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Frontotemporal lobar degeneration with TAR DNA-binding protein 43 (TDP-43): its journey of more than 100 years
Frontotemporal lobar degeneration (FTLD) with TDP-43-immunoreactive inclusions (FTLD–TDP) is a neurodegenerative disease associated with clinical,...
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The prevalence of osteoporosis/osteopenia in patients with multiple sclerosis (MS): a systematic review and meta-analysis
BackgroundThe prevalence of osteoporosis is reported differently. We designed this systematic review and meta-analysis to estimate pooled prevalence...
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Alzheimer’s disease and drug delivery across the blood–brain barrier: approaches and challenges
Alzheimer's disease (AD) is a diverse disease with a complex pathophysiology. The presence of extracellular β-amyloid deposition as neuritic plaques...
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Brain structural abnormalities and cognitive changes in a patient with 17q21.31 microduplication and early onset dementia: a case report
ObjectivesWe describe brain structural damage and cognitive profile evolution of an adult patient with 17q21.31 microduplication, a rare condition...
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Health care utilisation among older people with Down syndrome compared to specific medical guidelines for health surveillance: a Swedish national register study
BackgroundSpecific medical guidelines for health surveillance exist for people with Down syndrome (DS) since 25 years but knowledge of adherence to...
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Neuropharmacological potential of honokiol and its derivatives from Chinese herb Magnolia species: understandings from therapeutic viewpoint
Honokiol is a neolignan biphenol found in aerial parts of the Magnolia plant species. The Magnolia plant species traditionally belong to China and...