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Clinical characteristics and impact of comorbidities on the prognosis of senile epilepsy in Southwest China: a retrospective cohort study
BackgroundSenile epilepsy and its comorbidities pose a tremendous burden on patients and the society. This study was aimed to investigate the...
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Neurological Complications and Consequences of the Novel Coronavirus COVID-19 Infection in Elderly and Senile Patients (Literature Review)
AbstractBased on available publications, the article systematizes information about some forms of lesions of the central nervous system (CNS), their...
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Brain perfusion SPECT in dementia: what radiologists should know
The findings of brain perfusion single-photon emission computed tomography (SPECT), which detects abnormalities often before changes manifest in...
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Beyond Vision: A View from Eye to Alzheimer’s Disease and Dementia
With the aging of the global population, the health care burden of Alzheimer’s disease (AD) and dementia is considered to increase dramatically in...
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Novel insights into presenilin 1 mutation associated with a distinctive dementia phenotype and cotton wool plaques
BackgroundThe mutations in the presenilin 1 gene ( PSEN1 ) are the main cause of familial Alzheimer's disease. PSEN1 mutations affect amyloid-beta...
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Investigating the association between blood oxidative stress markers and dementia in Egyptian elderly women
BackgroundThe predicted increase in the senior population will have a substantial impact on mental health and dementia development, emphasizing the...
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Topical and subconjunctival anesthesia versus topical anesthesia alone in patients with senile cataracts undergoing phacoemulsification: a double-blind randomized controlled trial
BackgroundThis study compared topical anesthesia to a combination of topical anesthesia and subconjunctival anesthesia for phacoemulsification.
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Situating support for people living with rarer forms of dementia
BackgroundAwareness of a multitude of diseases that can cause neurodegenerative decline and their unique symptom profiles in the dementia care and...
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The Joint Effect of Body Mass Index and Serum Lipid Levels on Incident Dementia among Community-Dwelling Older Adults
ObjectivesThis study aimed to explore the joint effect of body mass index (BMI) and serum lipids levels on incident dementia.
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Effectiveness of creative story therapy for dementia: a systematic review and meta-analysis
ObjectiveTo conduct a meta-analysis of the effectiveness of creative story therapy versus routine nursing alone for the treatment of dementia.
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An investigation of psychoactive polypharmacy and related gender-differences in older adults with dementia: a retrospective cohort study
BackgroundOlder adults living with dementia may express challenging responsive behaviours. One management strategy is pharmacologic treatment though...
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Association of shift work with incident dementia: a community-based cohort study
BackgroundSome observational studies had found that shift work would increase risks of metabolic disorders, cancers, and cardiovascular diseases, but...
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Direct oral anticoagulants vs vitamin K antagonist on dementia risk in atrial fibrillation: systematic review with meta-analysis
Oral anticoagulation significantly reduces the incidence of dementia in atrial fibrillation patients. However, this protective effect has not been...
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MRI abnormalities in Creutzfeldt–Jakob disease and other rapidly progressive dementia
ObjectiveTo investigate brain MRI abnormalities in a cohort of patients with rapidly progressive dementia (RPD) with and without a diagnosis of...
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The adjusted impact of different severities of acute exacerbations and medications on the risk of develo** dementia in COPD patients
BackgroundAlthough a relationship between chronic obstructive pulmonary disease (COPD) and dementia has been reported, the initial severity upon...
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Trajectories of care of community-dwelling people living with dementia: a multidimensional state sequence analysis
BackgroundThe type and level of healthcare services required to address the needs of persons living with dementia fluctuate over disease progression....
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Fibrin-Targeting Immunotherapy for Dementia
Blood-brain barrier (BBB) disruption is an early event in the development of Alzheimer’s disease. It precedes extracellular deposition of amyloid-β...
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Similarities and differences in the prevalence and risk factors of suicidal behavior between caregivers and people with dementia: a systematic review
BackgroundPeople with dementia and their caregivers are prone to suicidal behaviors due to difficulty adjusting to their initial caregiving role and...
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Association of Diagnosed Dementia with Post-discharge Mortality and Readmission Among Hospitalized Medicare Beneficiaries
BackgroundPatients with dementia are frequently hospitalized and may face barriers in post-discharge care.
ObjectiveTo determine whether patients...
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Pathways explaining racial/ethnic and socio-economic disparities in incident all-cause dementia among older US adults across income groups
Differential racial and socioeconomic disparities in dementia incidence across income groups and their underlying mechanisms remain largely unknown....