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Best quality vs. sex selection – an analysis of embryo selection preferences for patients undergoing preimplantation genetic testing for aneuploidy over a 10-year period
PurposeInvestigate patient preferences in embryo selection for transfer regarding quality versus sex in IVF/ICSI cycles with PGT-A and assess...
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Sex ratio of offspring is not statistically altered following pre-implantation genetic testing under a specific sex selection policy
PurposeTo determine whether the use of pre-implantation genetic testing (PGT) under a specific sex selection policy is associated with alterations in...
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Identification of Novel Biomarkers for Response to Preoperative Chemoradiation in Locally Advanced Rectal Cancer with Genetic Algorithm–Based Gene Selection
BackgroundThe conventional treatment for patients with locally advanced colorectal tumors is preoperative chemo-radiotherapy (PCRT) preceding...
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Ultra-rare and common genetic variant analysis converge to implicate negative selection and neuronal processes in the aetiology of schizophrenia
Both common and rare genetic variants (minor allele frequency >1% and <0.1% respectively) have been implicated in the aetiology of schizophrenia. In...
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Disparities among infertility patients regarding genetic carrier screening, sex selection, and gene editing
PurposeThe purpose of this study is to evaluate the perspectives of infertility patients regarding genetic carrier screening, embryo sex selection,...
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The structure of psychiatric comorbidity without selection and assortative mating
The widespread comorbidity observed across psychiatric disorders may be the result of processes such as assortative mating, gene-environment...
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A decade of molecular preimplantation genetic diagnosis of 350 blastomeres for beta-thalassemia combined with HLA ty**, aneuploidy screening and sex selection in Iran
BackgroundPreimplantation genetic diagnosis (PGD) has been developed to detect genetic disorders before pregnancy which is usually done on...
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Genomics reveals heterogeneous Plasmodium falciparum transmission and selection signals in Zambia
BackgroundGenomic surveillance is crucial for monitoring malaria transmission and understanding parasite adaptation to interventions. Zambia lacks...
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Updates on Rare Genetic Variants, Genetic Testing, and Gene Therapy in Individuals With Obesity
Purpose of ReviewThe goal of this paper is to aggregate information on monogenic contributions to obesity in the past five years and to provide...
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Lung adenocarcinomas without driver genes converge to common adaptive strategies through diverse genetic, epigenetic, and niche construction evolutionary pathways
Somatic evolution selects cancer cell phenotypes that maximize survival and proliferation in dynamic environments. Although cancer cells are...
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Emerging trends in sperm selection: enhancing success rates in assisted reproduction
This comprehensive review explores the evolving landscape of sperm selection techniques within the realm of Assisted Reproductive Technology (ART)....
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Analysis of genetic selection at insulin receptor substrate-2 gene loci
PurposeType 2 diabetes mellitus (T2DM) is highly heritable and exhibits significant variability in prevalence between different populations....
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Islamic Perspectives on Polygenic Testing and Selection of IVF Embryos (PGT-P) for Optimal Intelligence and Other Non–Disease-Related Socially Desirable Traits
In recent years, the genetic testing and selection of IVF embryos, known as preimplantation genetic testing (PGT), has gained much traction in...
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Levodopa-carbidopa intestinal gel infusion (LCIG) in Parkinson disease with genetic mutations
BackgroundLevodopa-carbidopa intestinal gel infusion (LCIG) is a therapeutic option for advanced Parkinson disease (PD) patients with troublesome...
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Genetic association studies in critically ill patients: protocol for a systematic review
IntroductionPatients in the intensive care unit (ICU) are highly heterogeneous in characteristics, their clinical course, and outcomes. Genetic...
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Optimizing Gene Selection and Cancer Classification with Hybrid Sine Cosine and Cuckoo Search Algorithm
Gene expression datasets offer a wide range of information about various biological processes. However, it is difficult to find the important genes...
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Improved selection of participants in genetic longevity studies: family scores revisited
BackgroundAlthough human longevity tends to cluster within families, genetic studies on longevity have had limited success in identifying longevity...
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A step-by-step, multidisciplinary strategy to maximize the yield of genetic testing in pediatric patients with chronic kidney diseases
BackgroundThe use of genetic testing in pediatric patients with chronic kidney diseases (CKD) has increased exponentially in the past few years,...
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Toward Genetic Testing of Rivaroxaban? Insights from a Systematic Review on the Role of Genetic Polymorphism in Rivaroxaban Therapy
BackgroundInvestigations into the rivaroxaban response from the perspective of genetic variation have been relatively recent and wide in scope,...
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A novel embryo biopsy morphological analysis and genetic integrality criterion system significantly improves the outcome of preimplantation genetic testing
PurposeWhile efforts have been made to establish blastocyst grading systems in the past decades, little research has examined the quality of biopsy...
