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Asparagine reduces the risk of schizophrenia: a bidirectional two-sample mendelian randomization study of aspartate, asparagine and schizophrenia
BackgroundDespite ongoing research, the underlying causes of schizophrenia remain unclear. Aspartate and asparagine, essential amino acids, have been...
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Insulin Resistance/Diabetes and Schizophrenia: Potential Shared Genetic Factors and Implications for Better Management of Patients with Schizophrenia
Schizophrenia is a complex psychotic disorder with co-occurring conditions, including insulin resistance and type 2 diabetes (T2D). It is well...
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Differences in the neural correlates of schizophrenia with positive and negative formal thought disorder in patients with schizophrenia in the ENIGMA dataset
Formal thought disorder (FTD) is a clinical key factor in schizophrenia, but the neurobiological underpinnings remain unclear. In particular, the...
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Network-based drug repurposing for schizophrenia
Despite recent progress, the challenges in drug discovery for schizophrenia persist. However, computational drug repurposing has gained popularity as...
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Schizophrenia: **n, magic or disease? Experiences of family caregivers of patients with schizophrenia in Baloch ethnicity
BackgroundCultural and religious beliefs are effective on people’s attitudes towards schizophrenia and their help-seeking behaviors. This study aimed...
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Genetics and Schizophrenia
Purpose of reviewThis paper reviews modern literature describing the role of genetics in schizophrenia pathogenesis.
Recent findingsThe largest...
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Role of tDCS in Schizophrenia Management
Purpose of ReviewTranscranial Direct Current Stimulation (tDCS) is a non-invasive neuromodulation technique with potential clinical utility in...
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Mortality in patients with schizophrenia in Japan
PurposePatients with schizophrenia have a higher mortality risk than the general population. However, no recent studies have investigated mortality...
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Monozygotic twins discordant for schizophrenia differ in maturation and synaptic transmission
Schizophrenia affects approximately 1% of the world population. Genetics, epigenetics, and environmental factors are known to play a role in this...
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Altered Rbfox1-Vamp1 pathway and prefrontal cortical dysfunction in schizophrenia
Deficient gamma oscillations in prefrontal cortex (PFC) of individuals with schizophrenia appear to involve impaired inhibitory drive from...
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Multimorbidity and the Etiology of Schizophrenia
Purpose of ReviewA global study of multimorbidity in schizophrenia, especially of the association with physical conditions, might offer much needed...
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How much schizophrenia do famines cause?
Since the 1970s, famines have been widely invoked as natural experiments in research into the long-term impact of foetal exposure to nutritional...
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Threat Responses in Schizophrenia: A Negative Valence Systems Framework
Purpose of ReviewEmotions are prominent in theories and accounts of schizophrenia but are largely understudied compared to cognition. Utilizing the...
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Transitions in health insurance among continuously insured patients with schizophrenia
Changes in health insurance coverage may disrupt access to and continuity of care, even for those who remain insured. Continuity of care is...
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Linking childhood trauma to the psychopathology of schizophrenia: the role of oxytocin
Childhood trauma has been linked to schizophrenia, but underlying biological mechanisms remain elusive. This study explored the potential role of...
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Choroid plexus volume enlargement in first-episode antipsychotic-naïve schizophrenia
Investigation of the choroid plexus in schizophrenia has seen growing interest due to its role in the interaction between neuroinflammation and brain...
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Schizophrenia and risk preference: a bidirectional two-sample mendelian randomization study
Increasing evidence shows that risk preference is associated with schizophrenia. However, the causality and direction of this association are not...
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The contribution of prosody to machine classification of schizophrenia
We show how acoustic prosodic features, such as pitch and gaps, can be used computationally for detecting symptoms of schizophrenia from a single...
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Vocal emotion perception in schizophrenia and its diagnostic significance
BackgroundCognitive and emotional impairment are among the core features of schizophrenia; assessment of vocal emotion recognition may facilitate the...
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Copy number deletion of PLA2G4A affects the susceptibility and clinical phenotypes of schizophrenia
Phospholipase A2(PLA2) superfamily is recognized as being involved in the pathogenesis of schizophrenia by affecting lipid homeostasis in cell...
