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The diagnostic value of salivary C-reactive protein in neonatal infections: a meta-analysis
PurposeC-reactive protein (CRP), as an acute phase protein, is a sensitive indicator of neonatal bacterial infection. Some recent studies have shown...
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Associations between saliva and plasma cytokines in cognitively normal, older adults
BackgroundInflammatory responses play key roles in the development and progression of many pathological conditions, including neurodegenerative...
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Salivary metabolites as novel independent predictors of radiation pneumonitis
PurposeRadiotherapy is an integral treatment for non-small cell lung cancer (NSCLC); however, radiation-induced toxicities such as radiation...
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Ultrasound abnormalities of the major salivary glands in Egyptian patients with systemic sclerosis
Introduction/objectivessystemic sclerosis (SSc) is an autoimmune disorder with multiple organs destruction. This study aimed to identify the...
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Inflammatory cytokines and their potential role in Sjogren’s syndrome risk: insights from a mendelian randomization study
AimThis study aimed to investigate the causal impact of inflammatory cytokines on Sjogren’s Syndrome (SS) and to identify potential biomarkers for SS...
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Serum and salivary tissue transglutaminase IGA (tTG-IGA) level in celiac patients
BackgroundCeliac disease (CD) is a genetically determined autoimmune disease triggered by gluten consumption. Patients with these conditions have...
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Immunological subty** of salivary gland cancer identifies histological origin-specific tumor immune microenvironment
Gene expression analysis enhances proper cancer subty**, a better understanding of the molecular characteristics of cancer, and strategies for...
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Pathogenesis Analysis of Salivary Gland Tumors Through the Expression of Programmed Death-Ligand 1 (PD-L1)
Pleomorphic adenoma (PA) is the most common salivary gland neoplasm, followed by Warthin’s tumor (WT). In addition to its high frequency, PA also...
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In vitro effects of curcumin on proinflammatory cytokines and expression of their genes in minor salivary gland tissue of patients with Sjogren’s syndrome
Curcumin reduces disease severity and ameliorates lupus-like/Sjögren’s Syndrome-like disease in mice model. The immunological basis of these effects...
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The effect of non-surgical periodontal therapy on salivary IL-6 levels in patients with moderate to severe generalized chronic periodontitis
BackgroundGene regulation of IL-6 is characterized by the presence of inflammatory cytokines, bacterial products, viral infection, and activation of...
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DNA Damage-driven Inflammatory Cytokines: Reprogramming of Tumor Immune Microenvironment and Application of Oncotherapy
DNA damage occurs across tumorigenesis and tumor development. Tumor intrinsic DNA damage can not only increase the risk of mutations responsible for...
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Intraglandular mesenchymal stem cell treatment induces changes in the salivary proteome of irradiated patients
BackgroundHyposalivation and xerostomia (dry mouth), are the leading site-effects to treatment of head and neck cancer. Currently, there are no...
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Serum and salivary inflammatory biomarkers in juvenile idiopathic arthritis—an explorative cross-sectional study
BackgroundBiomarkers may be useful in monitoring disease activity in juvenile idiopathic arthritis (JIA). With new treatment options and treatment...
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Salivary microbiome profiling reveals a dysbiotic schizophrenia-associated microbiota
Schizophrenia is a debilitating mental disorder and often has a prodromal period, referred to as clinical high risk (CHR) for psychosis, prior to the...
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Myofibroblast and pro-fibrotic cytokines in fibrosis of IgG4-related disease (IgG4-RD) patients from South Asia: preliminary data
IntroductionFibrosis is a typical pathological characteristic in IgG4-RD patients and often irreversible. There exists a lack of suitable markers for...
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Prognostic Impact of Tumor Immune Microenvironment and Its Predictive Role in Salivary Gland Cancer
BackgroundRecently, many studies have investigated the role of tumor immune microenvironment (TIME) in carcinogenesis, highlighting its relation to...
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The expression and significance of vascular endothelial growth factor A in adenoid cystic carcinoma of palatal salivary gland
ObjectiveTo explore the VEGF-A expression in salivary gland adenoid cystic carcinoma tissues and detect the relationship between the mechanism of...
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Alterations of CD8+ T cells in the blood and salivary glands of patients with primary Sjögren’s syndrome
ObjectiveTo identify the alterations of CD8 + T cells in blood and labial salivary glands (LSGs) of patients with Primary Sjögren’s syndrome (pSS).
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Clinicopathological correlation of Cathepsin K expression in salivary gland carcinomas; relation to patients` outcome
BackgroundSalivary gland carcinomas (SGCs) represent various groups of tumors that demonstrate marked diversity in their prognosis owing to different...
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Morphofunctional state of the salivary glands of Wistar rats under prolonged exposure to alcohol
Chronic alcohol consumption has a negative impact on the submandibular and parotid salivary glands. The aim of this study was to study changes in...
