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Silencing LncRNA SNHG16 suppresses the diabetic inflammatory response by targeting the miR-212-3p/NF-κB signaling pathway
BackgroundLong noncoding RNAs (LncRNAs) have been identified to play an important role in diabetes. The aim of the present study was to determine the...
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LncRNA SNHG16 regulates RAS and NF-κB pathway-mediated NLRP3 inflammasome activation to aggravate diabetes nephropathy through stabilizing TLR4
AimsLncRNA SNHG16 and Toll-like receptor-4 (TLR4) participate in diabetes nephropathy. This study investigated whether SNHG16 regulates diabetic...
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Downregulation of lncRNA SNHG16 inhibits vascular smooth muscle cell proliferation and migration in cerebral atherosclerosis by targeting the miR-30c-5p/SDC2 axis
Atherosclerosis (AS) is the basic lesion underlying the occurrence and development of cerebrovascular diseases. Abnormal proliferation of vascular...
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Down-regulation of SNHG16 alleviates the acute lung injury in sepsis rats through miR-128-3p/HMGB3 axis
BackgroundLong noncoding RNAs contribute to various inflammatory diseases, including sepsis. We explore the role of small nucleolar RNA host gene 16...
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LncRNA SNHG16 promotes pulmonary fibrosis by targeting miR-455-3p to regulate the Notch2 pathway
BackgroundIdiopathic pulmonary fibrosis (IPF) is the most common interstitial lung diseases with a poor prognosis. Long non-coding RNAs (lncRNAs)...
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Breast cancer-derived exosomes transmit lncRNA SNHG16 to induce CD73+γδ1 Treg cells
γδT cells have been reported to exert immunosuppressive functions in multiple solid malignant diseases, but their immunosuppressive functional...
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Long non-coding RNAs in retinal neovascularization: current research and future directions
PurposeRetinal neovascularization (RNV) is an intractable pathological hallmark of numerous ocular blinding diseases, including diabetic retinopathy,...
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Evaluation of expression of VDR-associated lncRNAs in COVID-19 patients
BackgroundCoronavirus disease 2019 (COVID-19) has been shown to cause serious health problems among them is the Acute Respiratory Distress syndrome...
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LncRNA SNHG16 sponges miR-98-5p to regulate cellular processes in osteosarcoma
BackgroundAs has been illustrated that long noncoding RNAs (lncRNAs) and microRNAs (miRNAs) are potential regulators in the occurrence and...
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Combination of resveratrol and BIBR1532 inhibits proliferation of colon cancer cells by repressing expression of LncRNAs
Colorectal cancer (CRC) is the third most common cancer worldwide. The development of tumor drug resistance is observed in the treatment of CRC....
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The crucial roles of long noncoding RNA SNHGs in lung cancer
Lung cancer is one of the most common malignant tumors with growing morbidity and mortality worldwide. Several treatments are used to manage lung...
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Integrated bioinformatics and validation reveal SOX12 as potential biomarker in colon adenocarcinoma based on an immune infiltration-related ceRNA network
PurposeThe primary objective of this study was to construct competing endogenous RNA (ceRNA) networks and evaluate the prognostic significance of...
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Highlighting the role of long non-coding RNA (LncRNA) in multiple myeloma (MM) pathogenesis and response to therapy
Transcripts longer than 200 nucleotides that are not translated into proteins are known as long non-coding RNAs, or lncRNAs. Now, they are becoming...
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Long non-coding RNAs involved in retinoblastoma
IntroductionRetinoblastoma (RB) is the most common childhood tumor that can occur in the retina and develop in a sporadic or heritable form. Although...
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Exosomal noncoding RNAs as noninvasive biomarkers in bladder cancer: a diagnostic meta-analysis
BackgroundIn view of discordance consisting in different reports, a meta-analysis was conducted to comprehensively evaluate the diagnostic efficacy...
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Competitive endogenous network of circRNA, lncRNA, and miRNA in osteosarcoma chemoresistance
Osteosarcoma is the most prevalent and fatal type of bone tumor. Despite advancements in the treatment of other cancers, overall survival rates for...
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Identification of a disulfidptosis-related lncRNA signature for the prognostic and immune landscape prediction in head and neck squamous cell carcinoma
PurposeDisulfidptosis, a newly identified form of cell death, is triggered by disulfide stress. Herein, a unique signature was developed based on...
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Potentials of long non-coding RNAs as biomarkers of colorectal cancer
Colorectal cancer (CRC) is the third most common malignant tumor worldwide and the fourth major cause of cancer-related death, with high morbidity...
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Characterization of the long noncoding RNA transcriptome in human preimplantation embryo development
PurposeInfertility remains a human health burden globally. Only a fraction of embryos produced via assisted reproductive technologies (ARTs)...
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Role of miR-424 in the carcinogenesis
Recent studies have revealed the impact of microRNAs (miRNAs) in the carcinogenic process. miR-424 is a miRNA whose role in this process is being to...
