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Validation of \(^{99m}\)Tc and \(^{177}\)Lu quantification parameters for a Monte Carlo modelled gamma camera
PurposeMonte Carlo (MC) simulation in Nuclear Medicine is a powerful tool for modeling many physical phenomena which are difficult to track or...
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Analysis of a deep learning-based method for generation of SPECT projections based on a large Monte Carlo simulated dataset
BackgroundIn recent years, a lot of effort has been put in the enhancement of medical imaging using artificial intelligence. However, limited patient...
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Monte Carlo modelling of a compact CZT-based gamma camera with application to 177Lu imaging
BackgroundSemiconductor gamma-camera systems based on cadmium zinc telluride (CZT) detectors present new challenges due to an energy-response that...
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90Y SPECT scatter estimation and voxel dosimetry in radioembolization using a unified deep learning framework
Purpose90Y SPECT-based dosimetry following radioembolization (RE) in liver malignancies is challenging due to the inherent scatter and the poor...
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SPECT and CT misregistration reduction in [99mTc]Tc-MAA SPECT/CT for precision liver radioembolization treatment planning
PurposeRespiration and body movement induce misregistration between static [ 99m Tc]Tc-MAA SPECT and CT, causing lung shunting fraction (LSF) and...
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Position dependence of recovery coefficients in 177Lu-SPECT/CT reconstructions – phantom simulations and measurements
BackgroundAlthough the importance of quantitative SPECT has increased tremendously due to newly developed therapeutic radiopharmaceuticals, there are...
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Automatic delineation and quantification of pulmonary vascular obstruction index in patients with pulmonary embolism using Perfusion SPECT-CT: a simulation study
BackgroundIn patients with pulmonary embolism (PE), there is a growing interest in quantifying the pulmonary vascular obtruction index (PVOI), which...
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Accuracy of patient-specific I-131 dosimetry using hybrid whole-body planar-SPECT/CT I-123 and I-131 imaging
PurposeThis study aimed to assess the accuracy of patient-specific absorbed dose calculations for tumours and organs at risk in radiopharmaceutical...
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A multicentre simulation study of planar whole-body bone scintigraphy in Sweden
BackgroundWhole-body bone scintigraphy is a clinically useful non-invasive and highly sensitive imaging method enabling detection of metabolic...
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QCard-NM: Develo** a semiautomatic segmentation method for quantitative analysis of the right ventricle in non-gated myocardial perfusion SPECT imaging
BackgroundRecent studies have shown that the right ventricular (RV) quantitative analysis in myocardial perfusion imaging (MPI) SPECT can be...
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Biodistribution and dosimetry for combined [177Lu]Lu-PSMA-I&T/[225Ac]Ac-PSMA-I&T therapy using multi-isotope quantitative SPECT imaging
PurposeQuantitative SPECT for patient-specific dosimetry is a valuable tool in the scope of radionuclide therapy, although its clinical application...
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Verification of phantom accuracy using a Monte Carlo simulation: bone scintigraphy chest phantom
We aimed to compare the measurement and simulation data of bone scintigraphy of a chest phantom using a Monte Carlo simulation to verify the accuracy...
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Evaluation of Iodine-123 and Iodine-131 SPECT activity quantification: a Monte Carlo study
PurposeThe quantitative accuracy of Nuclear Medicine images, acquired for both planar and SPECT studies, is influenced by the isotope-collimator...
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Effect of ME Collimator Characteristic, Energy Window Width, and Reconstruction Algorithm Selection on Imaging Performance of Yttrium-90: Simulation Study
PurposeThe treatment efficiency of 90 Y and providing reliable estimates of activity are evaluated by SPECT imaging of bremsstrahlung radiation...
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The effect of calibration factors and recovery coefficients on 177Lu SPECT activity quantification accuracy: a Monte Carlo study
BackgroundDifferent gamma camera calibration factor (CF) geometries have been proposed to convert SPECT data into units of activity concentration....
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Machine learning-based prediction of conversion coefficients for I-123 metaiodobenzylguanidine heart-to-mediastinum ratio
PurposeWe developed a method of standardizing the heart-to-mediastinal ratio in 123 I-labeled meta -iodobenzylguanidine (MIBG) images using a...
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A deep neural network for fast and accurate scatter estimation in quantitative SPECT/CT under challenging scatter conditions
PurposeA major challenge for accurate quantitative SPECT imaging of some radionuclides is the inadequacy of simple energy window-based scatter...
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Capabilities of the Monte Carlo Simulation Codes for Modeling of a Small Animal SPECT Camera
PurposeThis study aims to compare Monte Carlo-based codes’ characteristics in the determination of the basic parameters of a high-resolution single...
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3D printed non-uniform anthropomorphic phantoms for quantitative SPECT
BackgroundA 3D printing grid-based method was developed to construct anthropomorphic phantoms with non-uniform activity distributions, to be used for...
