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Showing 1-20 of 265 results

  1. Detection method for reverse transcription recombinase-aided amplification of avian influenza virus subtypes H5, H7, and H9

    Background

    Avian influenza virus (AIV) not only causes huge economic losses to the poultry industry, but also threatens human health. Reverse...

    Zongshu Zhang, Zichuang Zhang, ... Tie Zhang in BMC Veterinary Research
    Article Open access 16 May 2024

  2. Loop-Mediated Isothermal Amplification–Based Microfluidic Platforms for the Detection of Viral Infections

    Purpose of Review

    Easy-to-use, fast, and accurate virus detection method is essential for patient management and epidemic surveillance, especially...

    Yuanyuan Zeng, Chuan Wu, Yang He in Current Infectious Disease Reports
    Article 02 November 2022

  3. CRISPR/Cas13-assisted hepatitis B virus covalently closed circular DNA detection

    Background and aims

    The formation of an intranuclear pool of covalently closed circular DNA (cccDNA) in the liver is the main cause of persistent...

    **angying Zhang, Yuan Tian, ... Feng Ren in Hepatology International
    Article Open access 17 March 2022

  4. Circular RNAs in kidney disease and cancer

    Circular RNAs (circRNAs) are a class of endogenously expressed regulatory RNAs with a single-stranded circular structure. They are generated by back...

    Anton Jan van Zonneveld, Malte Kölling, ... Johan M. Lorenzen in Nature Reviews Nephrology
    Article 11 August 2021

  5. Extrachromosomal circular DNA in colorectal cancer: biogenesis, function and potential as therapeutic target

    Extrachromosomal circular DNA (ecDNA) has gained renewed interest since its discovery more than half a century ago, emerging as critical driver of...

    Yinnan Chen, Quanpeng Qiu, ... Jun Yu in Oncogene
    Article Open access 01 March 2023

  6. The characteristics of extrachromosomal circular DNA in patients with end-stage renal disease

    Background

    End-stage renal disease (ESRD) is the final stage of chronic kidney disease (CKD). In addition to the structurally intact chromosome...

    Yue Peng, Yixi Li, ... Yong Dai in European Journal of Medical Research
    Article Open access 27 March 2023

  7. Circlehunter: a tool to identify extrachromosomal circular DNA from ATAC-Seq data

    In cancer, extrachromosomal circular DNA (ecDNA), or megabase-pair amplified circular DNA, plays an essential role in intercellular heterogeneity and...

    Manqiu Yang, Shufan Zhang, ... Moli Huang in Oncogenesis
    Article Open access 22 May 2023

  8. Prenatal screening for trisomy 21: a comparative performance and cost analysis of different screening strategies

    Background

    Prenatal screening for chromosome aneuploidies have constantly been evolving, especially with the introduction of cell-free fetal DNA...

    Tianhua Huang, Clare Gibbons, ... Wendy S. Meschino in BMC Pregnancy and Childbirth
    Article Open access 23 November 2020

  11. Leveraging extrachromosomal DNA to fine-tune trials of targeted therapy for glioblastoma: opportunities and challenges

    Glioblastoma evolution is facilitated by intratumour heterogeneity, which poses a major hurdle to effective treatment. Evidence indicates a key role...

    Imran Noorani, Paul S. Mischel, Charles Swanton in Nature Reviews Clinical Oncology
    Article 21 September 2022

  12. Extrachromosomal circular DNA: biogenesis, structure, functions and diseases

    Extrachromosomal circular DNA (eccDNA), ranging in size from tens to millions of base pairs, is independent of conventional chromosomes. Recently,...

    Ludi Yang, Ruobing Jia, ... **anqun Fan in Signal Transduction and Targeted Therapy
    Article Open access 02 October 2022

  13. New insight into circRNAs: characterization, strategies, and biomedical applications

    Circular RNAs (circRNAs) are a class of covalently closed, endogenous ncRNAs. Most circRNAs are derived from exonic or intronic sequences by...

    **n-Yi Feng, Shun-**n Zhu, ... Wen-Tao Wang in Experimental Hematology & Oncology
    Article Open access 12 October 2023

  14. Characterization of extrachromosomal circular DNAs in plasma of patients with clear cell renal cell carcinoma

    Background and Purpose

    Extrachromosomal circular DNAs (eccDNAs) have been recognized for their significant involvement in numerous biological...

    Qing Li, Rui-Xuan Zhang, ... Guo-Rong Li in World Journal of Urology
    Article 16 May 2024

  15. Predominance of low pathogenic avian influenza virus H9N2 in the respiratory co-infections in broilers in Tunisia: a longitudinal field study, 2018–2020

    Respiratory diseases are a health and economic concern for poultry production worldwide. Given global economic exchanges and migratory bird flyways,...

    Adam Jbenyeni, Guillaume Croville, ... Jean-Luc Guérin in Veterinary Research
    Article Open access 03 October 2023

  16. Tinea Pedis in Adolescents: A Comprehensive Review

    Purpose of Review

    The purpose of the review is to provide a detailed overview of athlete’s foot (tinea pedis) in adolescents, covering its causes,...

    Jose Ramón García-Lira, Mirna Eréndira Toledo-Bahena, ... Alexandro Bonifaz-Trujillo in Current Fungal Infection Reports
    Article 28 February 2024

  17. Spatial transcriptomics in health and disease

    The ability to localize hundreds of macromolecules to discrete locations, structures and cell types in a tissue is a powerful approach to understand...

    Sanjay Jain, Michael T. Eadon in Nature Reviews Nephrology
    Article 08 May 2024

  18. Going circular: history, present, and future of circRNAs in cancer

    To date, thousands of highly abundant and conserved single-stranded RNA molecules shaped into ring structures (circRNAs) have been identified....

    Giuseppina Pisignano, David C. Michael, ... George A. Calin in Oncogene
    Article Open access 16 August 2023

  19. Microfluidics-based strategies for molecular diagnostics of infectious diseases

    Traditional diagnostic strategies for infectious disease detection require benchtop instruments that are inappropriate for point-of-care testing...

    **n Wang, **an-Zhe Hong, ... Bi-Feng Liu in Military Medical Research
    Article Open access 18 March 2022

  20. MicroRNA amplification and detection technologies: opportunities and challenges for point of care diagnostics

    The volume of point of care (POC) testing continues to grow steadily due to the increased availability of easy-to-use devices, thus making it...

    Vivek Priy Dave, Tien Anh Ngo, ... Dang Duong Bang in Laboratory Investigation
    Article 12 December 2018
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