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Showing 1-20 of 3,680 results
  1. Choroidal and retinal vascular changes in HLA-B27-associated anterior uveitis

    Purpose

    To quantitatively analyze choroidal and retinal vascular changes in HLA-B27-associated anterior uveitis.

    Study Design

    A retrospective study.

    ...
    Heejeong Chun, Joo Young Kim, ... Young-Hoon Park in Japanese Journal of Ophthalmology
    Article 05 July 2024
  2. GSDMD-mediated pyroptosis in retinal vascular inflammatory diseases: a review

    Purpose

    Pyroptosis is a newly discovered form of programmed pro-inflammatory cell death. The main signaling pathways include the classical scorch...

    Li **aodong, **e Xuejun in International Ophthalmology
    Article 07 September 2022
  3. Evaluation of retinal and optic disc vascular structures in patients with familial Mediterranean fever (FMF) via optical coherence tomography angiography

    Introduction

    Familial Mediterranean fever (FMF) is an auto-immune disease characterized by fever and serositis. With this study, we aimed at comparing...

    Mehmet Bulut, Oznur Kutluk, ... Hasan Fatih Cay in International Ophthalmology
    Article 16 December 2022
  4. The effect of palm oil-derived tocotrienol-rich fraction in preserving normal retinal vascular diameter in streptozotocin-induced diabetic rats

    Purpose

    Angiogenesis in diabetic retinopathy (DR) is associated with increased retinal expression of angiopoietin-2 (Ang-2) and protein kinase C...

    Nurliyana Ain Abdul Ghani, Nurul Alimah Abdul Nasir, ... Norlina Ramli in Graefe's Archive for Clinical and Experimental Ophthalmology
    Article 09 January 2023
  5. Alterations in the choroidal thickness and retinal vascular caliber in keratoconus

    Purpose

    To compare the choroidal thickness (CT) and retinal vascular caliber in the differentiation of patients who have keratoconus (KC) from those...

    Gözde Aksoy Aydemir, Dilara Ozkoyuncu Kocabas, ... Ayse Sevgi Karadağ in International Ophthalmology
    Article 01 July 2022
  6. Retinal detachment

    Retinal detachment (RD) occurs when the neurosensory retina, the neurovascular tissue responsible for phototransduction, is separated from the...

    Jonathan B. Lin, Raja Narayanan, ... Rajendra S. Apte in Nature Reviews Disease Primers
    Article 14 March 2024
  7. TRIM46 aggravated high glucose-induced hyper permeability and inflammatory response in human retinal capillary endothelial cells by promoting IκBα ubiquitination

    Background

    Diabetic retinopathy (DR) as a severe diabetic complication contributes to blindness. The increased permeability of retinal capillary...

    Hangqi Shen, Qiaoyun Gong, ... Dawei Luo in Eye and Vision
    Article Open access 05 September 2022
  8. Correlation of retinal vascular characteristics with laboratory and ocular findings in Fabry disease: exploring ocular diagnostic biomarkers

    Background

    The goal of this study was to evaluate macular microvascular changes in patients with Fabry disease (FD) using optical coherence tomography...

    Migle Lindziute, Jessica Kaufeld, ... Katerina Hufendiek in Orphanet Journal of Rare Diseases
    Article Open access 08 October 2023
  9. Chronic sildenafil citrate use decreases retinal vascular endothelial growth factor expression in diabetic rats: a pilot study

    Background

    Sildenafil citrate (SC) attenuates endothelial dysfunction. However, its effects on diabetic retinopathy (DR), which is mainly a...

    Osama A. Sorour, Elsayed Nassar, ... Dina Tadros in International Journal of Retina and Vitreous
    Article Open access 17 July 2023
  10. Simultaneous attenuation of hyperglycemic memory-induced retinal, pulmonary, and glomerular dysfunctions by proinsulin C-peptide in diabetes

    Background

    Hyperglycemic memory (HGM) is a pivotal phenomenon in the development of diabetic complications. Although coincident diabetic complications...

    Hye-Yoon Jeon, Chan-Hee Moon, ... Kwon-Soo Ha in BMC Medicine
    Article Open access 13 February 2023
  11. Retinal VIP-amacrine cells: their development, structure, and function

    Amacrine cells (ACs) are the most structurally and functionally diverse neuron type in the retina. Different ACs have distinct functions, such as...

    Xuhong Zhang, **aoyu Wang, ... Ye Shen in Eye
    Article 08 December 2023
  12. Rate and associations of inner retinal thinning in eyes with retinal vein occlusion and regressed macular oedema

    Purpose

    To investigate the associations between visual acuity (VA) and structural optical coherence tomography (OCT) features in retinal vein...

    Maria Vittoria Cicinelli, Lamberto La Franca, ... Francesco Bandello in Eye
    Article 30 June 2023
  13. Retinal microvasculature and cerebral hemodynamics in patients with internal carotid artery stenosis

    Purpose

    To investigate the relationship between retinal microvasculature and cerebral hemodynamics in patients with internal carotid artery (ICA)...

    Junfeng Liu, **cheng Wan, ... Bo Wu in BMC Neurology
    Article Open access 13 October 2022
  14. Longitudinal analysis of aqueous humour cytokine expression and OCT-based imaging biomarkers in retinal vein occlusions treated with anti-vascular endothelial growth factor therapy in the IMAGINE study

    Background/objectives

    Retinal vein occlusion (RVO) is the second most common retinal vascular disorder. Despite promising advances with anti-VEGF...

    Sruthi Arepalli, Charles C. Wykoff, ... Justis P. Ehlers in Eye
    Article 11 October 2022
  15. Human retinal endothelial cells express functional interleukin-6 receptor

    Background

    Interleukin (IL)-6 is an inflammatory cytokine present in the eye during non-infectious uveitis, where it contributes to the progression of...

    Lisia Barros Ferreira, Liam M. Ashander, ... Justine R. Smith in Journal of Ophthalmic Inflammation and Infection
    Article Open access 25 April 2023
  16. A fluorescein angiography-based computer-aided algorithm for assessing the retinal vasculature in diabetic retinopathy

    Objective

    To present a fluorescein angiography (FA)‒based computer algorithm for quantifying retinal blood flow, perfusion, and permeability, in...

    Amir Abbasnejad, Oren Tomkins-Netzer, ... Jaime Levy in Eye
    Article 28 May 2022
  17. VEGF-induced Nrdp1 deficiency in vascular endothelial cells promotes cancer metastasis by degrading vascular basement membrane

    Vascular endothelial cells (VECs) are key players in the formation of neovessels and tumor metastasis, the ultimate cause of the majority of...

    Qing-Qing Li, Meng Guo, ... Guo-Qiang Chen in Oncogene
    Article 23 April 2024
  18. Diabetic vascular diseases: molecular mechanisms and therapeutic strategies

    Vascular complications of diabetes pose a severe threat to human health. Prevention and treatment protocols based on a single vascular complication...

    Yiwen Li, Yanfei Liu, ... Yue Liu in Signal Transduction and Targeted Therapy
    Article Open access 10 April 2023
  19. Vascular Endothelial Growth Factor C and D Signaling Pathways as Potential Targets for the Treatment of Neovascular Age-Related Macular Degeneration: A Narrative Review

    The development of treatments targeting the vascular endothelial growth factor (VEGF) signaling pathways have traditionally been firstly investigated...

    Ian M. Leitch, Michael Gerometta, ... Megan E. Baldwin in Ophthalmology and Therapy
    Article Open access 01 June 2024
  20. Atrophy of retinal vessels in neovascular age-related macular degeneration following long-term treatment with 20 intravitreal anti-VEGF injections

    Background

    The study aimed to evaluate the changes in retinal vascular density in exudative age-related macular degeneration (AMD) after long-term...

    Miklós D. Resch, Aniko Balogh, ... András Papp in BMC Ophthalmology
    Article Open access 05 December 2022
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