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Choroidal and retinal vascular changes in HLA-B27-associated anterior uveitis
PurposeTo quantitatively analyze choroidal and retinal vascular changes in HLA-B27-associated anterior uveitis.
Study DesignA retrospective study.
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GSDMD-mediated pyroptosis in retinal vascular inflammatory diseases: a review
PurposePyroptosis is a newly discovered form of programmed pro-inflammatory cell death. The main signaling pathways include the classical scorch...
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Evaluation of retinal and optic disc vascular structures in patients with familial Mediterranean fever (FMF) via optical coherence tomography angiography
IntroductionFamilial Mediterranean fever (FMF) is an auto-immune disease characterized by fever and serositis. With this study, we aimed at comparing...
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The effect of palm oil-derived tocotrienol-rich fraction in preserving normal retinal vascular diameter in streptozotocin-induced diabetic rats
PurposeAngiogenesis in diabetic retinopathy (DR) is associated with increased retinal expression of angiopoietin-2 (Ang-2) and protein kinase C...
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Alterations in the choroidal thickness and retinal vascular caliber in keratoconus
PurposeTo compare the choroidal thickness (CT) and retinal vascular caliber in the differentiation of patients who have keratoconus (KC) from those...
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Retinal detachment
Retinal detachment (RD) occurs when the neurosensory retina, the neurovascular tissue responsible for phototransduction, is separated from the...
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TRIM46 aggravated high glucose-induced hyper permeability and inflammatory response in human retinal capillary endothelial cells by promoting IκBα ubiquitination
BackgroundDiabetic retinopathy (DR) as a severe diabetic complication contributes to blindness. The increased permeability of retinal capillary...
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Correlation of retinal vascular characteristics with laboratory and ocular findings in Fabry disease: exploring ocular diagnostic biomarkers
BackgroundThe goal of this study was to evaluate macular microvascular changes in patients with Fabry disease (FD) using optical coherence tomography...
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Chronic sildenafil citrate use decreases retinal vascular endothelial growth factor expression in diabetic rats: a pilot study
BackgroundSildenafil citrate (SC) attenuates endothelial dysfunction. However, its effects on diabetic retinopathy (DR), which is mainly a...
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Simultaneous attenuation of hyperglycemic memory-induced retinal, pulmonary, and glomerular dysfunctions by proinsulin C-peptide in diabetes
BackgroundHyperglycemic memory (HGM) is a pivotal phenomenon in the development of diabetic complications. Although coincident diabetic complications...
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Retinal VIP-amacrine cells: their development, structure, and function
Amacrine cells (ACs) are the most structurally and functionally diverse neuron type in the retina. Different ACs have distinct functions, such as...
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Rate and associations of inner retinal thinning in eyes with retinal vein occlusion and regressed macular oedema
PurposeTo investigate the associations between visual acuity (VA) and structural optical coherence tomography (OCT) features in retinal vein...
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Retinal microvasculature and cerebral hemodynamics in patients with internal carotid artery stenosis
PurposeTo investigate the relationship between retinal microvasculature and cerebral hemodynamics in patients with internal carotid artery (ICA)...
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Longitudinal analysis of aqueous humour cytokine expression and OCT-based imaging biomarkers in retinal vein occlusions treated with anti-vascular endothelial growth factor therapy in the IMAGINE study
Background/objectivesRetinal vein occlusion (RVO) is the second most common retinal vascular disorder. Despite promising advances with anti-VEGF...
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Human retinal endothelial cells express functional interleukin-6 receptor
BackgroundInterleukin (IL)-6 is an inflammatory cytokine present in the eye during non-infectious uveitis, where it contributes to the progression of...
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A fluorescein angiography-based computer-aided algorithm for assessing the retinal vasculature in diabetic retinopathy
ObjectiveTo present a fluorescein angiography (FA)‒based computer algorithm for quantifying retinal blood flow, perfusion, and permeability, in...
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VEGF-induced Nrdp1 deficiency in vascular endothelial cells promotes cancer metastasis by degrading vascular basement membrane
Vascular endothelial cells (VECs) are key players in the formation of neovessels and tumor metastasis, the ultimate cause of the majority of...
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Diabetic vascular diseases: molecular mechanisms and therapeutic strategies
Vascular complications of diabetes pose a severe threat to human health. Prevention and treatment protocols based on a single vascular complication...
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Vascular Endothelial Growth Factor C and D Signaling Pathways as Potential Targets for the Treatment of Neovascular Age-Related Macular Degeneration: A Narrative Review
The development of treatments targeting the vascular endothelial growth factor (VEGF) signaling pathways have traditionally been firstly investigated...
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Atrophy of retinal vessels in neovascular age-related macular degeneration following long-term treatment with 20 intravitreal anti-VEGF injections
BackgroundThe study aimed to evaluate the changes in retinal vascular density in exudative age-related macular degeneration (AMD) after long-term...