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Metabolic remodelling in atrial fibrillation: manifestations, mechanisms and clinical implications
Atrial fibrillation (AF) is a continually growing health-care burden that often presents together with metabolic disorders, including diabetes...
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The effect of bariatric surgery type on cardiac reverse remodelling
IntroductionBariatric surgery is effective in reversing adverse cardiac remodelling in obesity. However, it is unclear whether the three commonly...
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Limited angular remodelling after in-situ fixation for slipped capital femoral epiphysis
BackgroundIn Sweden, most children with slipped capital femoral epiphysis (SCFE) are operated on with a single smooth pin or a short-threaded screw,...
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Maternal obesity and offspring cardiovascular remodelling — the effect of preconception and antenatal lifestyle interventions: a systematic review
BackgroundPreconception or antenatal lifestyle interventions in women with obesity may prevent adverse cardiovascular outcomes in the child,...
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The amount of hyaluronic acid and airway remodelling increase with the severity of inflammation in neutrophilic equine asthma
BackgroundEquine asthma (EA) is a chronic lower airway inflammation that leads to structural and functional changes. Hyaluronic acid (HA) has crucial...
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Role of echocardiography on early diagnosis of atrial remodelling and fibrosis in elite athletes
There is emerging data indicating that long-standing vigorous exercise may be associated with atrial structural remodelling. This remodelling process...
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Cubitus varus deformity following paediatric supracondylar humeral fracture remodelling predominantly in the sagittal direction: A three-dimensional analysis of eighty-six cases
PurposeThree-dimensional (3D) capacity for remodelling in cubitus varus deformity (CVD) after paediatric supracondylar humeral fractures (PSHFs)...
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Role of monocytes and dendritic cells in cardiac reverse remodelling after cardiac resynchronization therapy
Background and aimsMonocytes and dendritic cells (DC) are both key inflammatory cells, with recognized effects on cardiac repair. However, there are...
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Circulating sphingolipids and relationship to cardiac remodelling before and following a low-energy diet in asymptomatic Type 2 Diabetes
BackgroundHeart failure with preserved ejection fraction (HFpEF) is a heterogenous multi-system syndrome with limited efficacious treatment options....
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Fibro-fatty remodelling in arrhythmogenic cardiomyopathy
Arrhythmogenic cardiomyopathy (AC) is an inherited disorder characterized by lethal arrhythmias and a risk to sudden cardiac death. A hallmark...
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Left ventricular mass predicts cardiac reverse remodelling in patients treated with empagliflozin
BackgroundThe cardiovascular (CV) benefits of sodium-glucose transport protein 2 inhibitors have been attributed, in part, to cardiac reverse...
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Pharmacological Anti-Remodelling Effects of Disease-Modifying Drugs in Heart Failure with Reduced Ejection Fraction
Cardiac remodelling is an adverse phenomenon linked to heart failure progression and an important contributor to heart failure severity. Cardiac...
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Acute intra-cavity 4D flow cardiovascular magnetic resonance predicts long-term adverse remodelling following ST-elevation myocardial infarction
BackgroundDespite advancements in percutaneous coronary intervention, a significant proportion of ST-elevation myocardial infarction (STEMI)...
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Serum concentration of dickkopf-related protein 1 (DKK1) in psoriatic arthritis in the context of bone remodelling
Psoriatic arthritis (PsA) is a chronic inflammatory disease, characterised by the pathological occurrence of two opposite phenomena—osteoresorption...
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Left ventricular remodelling in rheumatic heart disease – trends over time and implications for follow-up in childhood
BackgroundRheumatic heart disease (RHD) is the most common form of acquired heart disease worldwide. In RHD, volume loading from mitral regurgitation...
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Lifestyle intervention in obese pregnancy and cardiac remodelling in 3-year olds: children of the UPBEAT RCT
Background/ObjectivesObesity in pregnancy has been associated with increased childhood cardiometabolic risk and reduced life expectancy. The UK...
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Cardiac metabolic remodelling in chronic kidney disease
Chronic kidney disease (CKD) affects millions of people globally and, for most patients, the risk of develo** cardiovascular disease is higher than...