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The potential value of ultrasound in predicting local refractory/relapse events in primary thyroid lymphoma patients
BackgroundPrimary thyroid lymphoma (PTL) is a rare malignant disorder, and ultrasound plays an important role in PTL diagnosis and follow-up...
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Treatment of children with refractory/relapse high risk langerhans cell histiocytosis with the combination of cytarabine, vindesine and prednisone
BackgroundThe patients with multisystem and risk organ involvement Langerhans cell histiocytosis (MS-RO + LCH) have poor prognosis. The patients with...
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CD4 + and CD8 + T-lymphocyte number as predictive marker of relapse after rituximab treatment in childhood-onset refractory nephrotic syndrome
BackgroundRituximab is a promising option for refractory idiopathic nephrotic syndrome. However, no simple predictive markers for relapse after...
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Identification of potential resistance mechanisms and therapeutic targets for the relapse of BCMA CAR-T therapy in relapsed/refractory multiple myeloma through single-cell sequencing
BackgroundBCMA CAR-T is highly effective for relapsed/refractory multiple myeloma(R/R-MM) and significantly improves the survival of patients....
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The impact of current therapeutic options on the health-related quality of life of patients with relapse/refractory multiple myeloma: a systematic review of clinical studies
PurposePatients with relapse and/or refractory multiple myeloma (RRMM) have a high disease burden with poor health-related quality of life (HRQoL)...
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Identification of prognostic factors and construction of a nomogram for patients with relapse/refractory adult-onset Still’s disease
ObjectivesThis study aimed to identify the risk factors for relapse/refractory adult-onset Still’s disease (AOSD) and to construct and validate a...
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Efficacy of combination of venetoclax with azacitidine or chemotherapy in refractory/relapse acute leukemias of ambiguous lineage, not otherwise specified
Acute leukemias of ambiguous lineage, not otherwise specified (ALAL-NOS) is a rare type of acute leukemia. Management of relapse/refractory (R/R)...
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A real-world analysis of PD1 blockade from the Rete Ematologica Pugliese (REP) in patients with relapse/refractory Hodgkin’s lymphoma
Checkpoint inhibitors have significantly changed the prognosis of patients with relapsing refractory classical Hodgkin’s lymphoma (cHL),...
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Allogeneic stem cell transplantation as a curative option in relapse/refractory diffuse large B cell lymphoma: Spanish multicenter GETH/GELTAMO study
We performed a retrospective multicenter study including 140 patients with relapsed/refractory (R/R) diffuse large B cell lymphoma (DLBCL) who...
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Correction to: Eltrombopag is effective in patients with relapse/refractory aplastic anemia—report from a single center in China
The article “Eltrombopag is effective in patients with relapse/refractory aplastic anemia—report from a single center in China”.
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Relationship between mucosal healing by tacrolimus and relapse of refractory ulcerative colitis: a retrospective study
BackgroundTacrolimus (TAC) is a powerful remission-inducing drug for refractory ulcerative colitis (UC). However, it is unclear whether mucosal...
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Decitabine combined with low-dose cytarabine, aclarubicin and rhG-CSF regimen may be a potential alternative for relapsed/refractory acute myeloid leukemia: A single-center study
PurposeTo analyze the effectiveness of decitabine combined with low-dose Ara‑C, aclarubicin, and rhG-CSF (DCAG) as a salvage therapy in patients with...
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Regular assessment of serum vascular endothelial growth factor levels to monitor POEMS syndrome
BackgroundTo investigate the utility of regular serum VEGF (sVEGF) levels assessment in the monitoring of POEMS syndrome.
MethodsWe retrospectively...
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Survival advantage of treosulfan plus fludarabine (FT14) compared to busulfan plus fludarabine (FB4) in active acute myeloid leukemia post allogeneic transplantation: an analysis from the European Society for Blood and Marrow Transplantation (EBMT) Acute Leukemia Working Party (ALWP)
We compared FT14 (fludarabine 150–160 mg/m 2 , treosulfan 42 g/m 2 ) versus FB4 (fludarabine 150–160 mg/m 2 , busulfan 12.8 mg/kg) in acute myeloid...
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Novel CAR T cell therapies for patients with large B cell lymphoma
Approximately 60–70% of patients with large B cell lymphoma (LBCL) achieve long-term remission or a cure after initial treatment. However, patients...
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Impact of disease burden on clinical outcomes of AML patients receiving allogeneic hematopoietic cell transplantation: a study from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation
Pre-transplant detectable measurable residual disease (MRD) is still associated with high risk of relapse and poor outcomes in acute myeloid leukemia...
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Challenges in Administering Salvage Therapy and Outcomes of Relapsed/Refractory Diffuse Large B-Cell Lymphoma Patients: A LMIC Real-World Study
Standard therapy for patients with Relapsed/Refractory Diffuse Large B-Cell Lymphoma (RR DLBCL) involves salvage chemotherapy followed by autologous...
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Impact of minimal residual disease response and of status of disease on survival after blinatumomab in B-cell acute lymphoblastic leukemia: results from a real-life study
Blinatumomab is a bispecific T-cell engager approved for relapsed/refractory and minimal residual disease positive B-cell Acute Lymphoblastic...