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Evaluating the effectiveness of Uganda’s Supranational TB Reference Laboratory quality management system training program
BackgroundAchieving the targeted organizational goals through effective training can increase employee satisfaction. Since 2015, the Supranational...
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Specificity of serological screening tests and reference laboratory tests to diagnose gambiense human African trypanosomiasis: a prospective clinical performance study
BackgroundSerological screening tests play a crucial role to diagnose gambiense human African trypanosomiasis (gHAT). Presently, they preselect...
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Seasonally adjusted laboratory reference intervals to improve the performance of machine learning models for classification of cardiovascular diseases
BackgroundVariation in laboratory healthcare data due to seasonal changes is a widely accepted phenomenon. Seasonal variation is generally not...
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Diagnostic accuracy of the Xpert® MTB/XDR assay for detection of Isoniazid and second-line antituberculosis drugs resistance at central TB reference laboratory in Tanzania
IntroductionEarly diagnosis of tuberculosis (TB) and universal access to drug-susceptibility testing (DST) are critical elements of the WHO End TB...
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Sensitivity and specificity of OraQuick® HIV self-test compared to a 4th generation laboratory reference standard algorithm in urban and rural Zambia
BackgroundHIV self-testing (HIVST) has the potential to increase coverage of HIV testing, but concerns exist about intended users’ ability to...
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Laboratory Manual for Mohs Micrographic Surgery Frozen Tissue Processing
This manual provides a thorough and up-to-date reference on the Mohs tissue processing technique. Mohs micrographic surgery is a distinct surgical...
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Publication Recommendations to Report Laboratory Data of Neonates – a Modified Delphi Approach
BackgroundClinical and analytical information on laboratory data of neonates in scientific publications is sparse and incomplete. Furthermore,...
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Performance of clinical signs and symptoms, rapid and reference laboratory diagnostic tests for diagnosis of human African trypanosomiasis by passive screening in Guinea: a prospective diagnostic accuracy study
BackgroundPassive diagnosis of human African trypanosomiasis (HAT) at the health facility level is a major component of HAT control in Guinea. We...
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Extracting laboratory test information from paper-based reports
BackgroundIn the healthcare domain today, despite the substantial adoption of electronic health information systems, a significant proportion of...
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Clinical and Laboratory Medicine Textbook
This textbook describes several diseases and clinical conditions, from physiopathological mechanisms to main clinical pictures, highlighting the...
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Evolution of a laboratory mechanomyograph
Mechanomyography is currently the accepted laboratory reference standard for quantitative neuromuscular blockade monitoring. Mechanomyographs are not...
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The publication quality of laboratory values in clinical studies in neonates
BackgroundThere are no generally accepted age-appropriate reference ranges for laboratory values in neonates. This also matters for drug development....
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Validation of Oura ring energy expenditure and steps in laboratory and free-living
BackgroundCommercial activity trackers are increasingly used in research and compared with research-based accelerometers are often less intrusive,...
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Infant liver biochemistry is different than current laboratory accepted norms
The purpose is to study liver biochemistry in a well-defined cohort of term infants. The methods include healthy term infants ( n = 619) provided...
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Comparison of reference distributions acquired by direct and indirect sampling techniques: exemplified with the Pediatric Reference Interval in China (PRINCE) study
BackgroundOur study aimed to compare the reference distributions of serum creatinine and urea obtained by direct sampling technique and two indirect...
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Inter-laboratory comparison of routine autoantibody detection methods for autoimmune neuropathies and myasthenia gravis
Serological tests are important to detect autoantibodies (autoAbs) in patients with autoimmune neuropathies (AN) and myasthenia gravis (MG) as they...
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An Indian perspective for umbilical cord blood haematological parameters reference interval
BackgroundThe Haematological Reference Intervals (RIs) are prone to vary on the basis of various factors such as altitude, age, sex, socioeconomic...
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Comprehensive reference intervals for white blood cell counts during pregnancy
BackgroundWhite blood cell (WBC) count increases during pregnancy, necessitating reliable reference intervals for assessing infections and...
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European LeukemiaNet laboratory recommendations for the diagnosis and management of chronic myeloid leukemia
From the laboratory perspective, effective management of patients with chronic myeloid leukemia (CML) requires accurate diagnosis, assessment of...
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Haematological reference intervals for pregnant Icelandic mares on pasture
BackgroundFew studies have been conducted on haematological reference intervals (RIs) in Icelandic horses. Reference intervals have been published...
