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Risk Factor Analysis of Lymph Node Metastasis for Rectal Neuroendocrine Tumors: Who Needs a Radical Resection in Rectal Neuroendocrine Tumors Sized 1–2 cm?
BackgroundRectal neuroendocrine tumors (NETs) have malignant potential, and lymph node (LN) or distant metastases can occur; however, treatment of...
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Immunoreactivity of HOXB13 in Neuroendocrine Neoplasms Is a Sensitive and Specific Marker of Rectal Well-Differentiated Neuroendocrine Tumors
HoxB13 is a transcription factor involved in defining of posterior endodermal derivatives, including prostate and rectum. While it is used as a...
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When is neoadjuvant chemotherapy indicated in rectal neuroendocrine tumors? An analysis of the National Cancer Database
BackgroundRectal neuroendocrine tumors (rNET) are rare and challenging to manage. While most patients with small rNET can be definitively treated...
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Efficacy of Endoscopic Resection for Rectal Neuroendocrine Tumors Smaller than 15 mm
BackgroundLocal resection, including endoscopic resection, is recommended for rectal neuroendocrine tumors (NETs) < 15 mm in patients without risk...
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Clinicopathological characteristics of rectal multiple neuroendocrine neoplasms and literature review
BackgroundThere are only a few epidemiological reports available for reference. The clinicopathological features are not clear, so there is no...
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Impact of grade on workup of rectal neuroendocrine tumors: a retrospective cohort study
BackgroundRectal neuroendocrine tumors (RNETs) are often discovered on screening colonoscopy. Indications for staging and definitive resection are...
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Long-term clinical outcomes of endoscopic submucosal dissection in rectal neuroendocrine tumors based on resection margin status: a real-world study
BackgroundEndoscopic submucosal dissection (ESD) has been widely adopted in treating rectal neuroendocrine tumors (NETs). However, clinical outcomes...
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The role of endoscopic ultrasonography for diagnosis of residual rectal neuroendocrine tumor
BackgroundEndoscopic ultrasonography (EUS) is useful for assessing the depth and regional lymph node involvement in rectal neuroendocrine tumors...
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Underwater endoscopic mucosal resection for rectal neuroendocrine tumors (with videos): a single center retrospective study
BackgroundUnderwater endoscopic mucosal resection (UMER) is a new method of endoscopic resection to completely remove the lesion without submucosal...
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The Clinicopathological Significance of Tumor Cell Subty** in Appendiceal Neuroendocrine Tumors: A Series of 135 Tumors
Appendiceal neuroendocrine tumors (NETs) are common and often are identified as incidental lesions at the time of appendectomy. The guidelines for...
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Multiple distant metastases arising from a single, low-grade rectal neuroendocrine tumor: an autopsy case report
BackgroundRectal neuroendocrine neoplasms are rare epithelial neoplasms of the rectum. The incidence of these tumors has increased over the past...
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Liver metastasis from rectal neuroendocrine neoplasm detected 15 years after primary resection
BackgroundRectal neuroendocrine neoplasms can induce liver metastasis. However, few reports exist on the associated long-term recurrence rates. We...
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Current status of the role of endoscopy in evaluation and management of gastrointestinal and pancreatic neuroendocrine tumors
The incidence of gastroenteropancreatic neuroendocrine tumors (GEP-NETs) has increased over the last several decades. In general, NETs are...
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Efficacy of endoscopic submucosal resection with a ligation device for small rectal neuroendocrine tumor: study protocol of a multicenter open-label randomized control trial (BANDIT trial)
BackgroundEndoscopic resection is widely accepted as a local treatment for rectal neuroendocrine tumors sized ≤ 10 mm. However, there is no consensus...
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Mixed high-grade serous and large cell neuroendocrine carcinoma arising from rectal endometriosis 11 years after hysterectomy
The malignant gastrointestinal endometriosis transformation is represented by endometriosis-associated intestinal tumors. Endometrioid adenocarcinoma...
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Comparison between endoscopic mucosal resection with a cap and endoscopic submucosal dissection for rectal neuroendocrine tumors
BackgroundThe aim of this study is to evaluate and compare the safety and efficacy of endoscopic mucosal resection with a cap (EMR-c) with those of...
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Clinical outcomes and risk factors associated with poor prognosis after endoscopic resection of 10–20 mm rectal neuroendocrine tumors: a multicenter, retrospective study of 10-year experience
BackgroundThe efficacy of endoscopic resection for of 10–20 mm rectal neuroendocrine tumor (NET) remains controversial. We aimed to evaluate the...
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A case of a tiny neuroendocrine carcinoma in a large flat-elevated rectal tumor causing multiple liver metastases
Neuroendocrine tumors are rare malignancies comprising neuroendocrine cells widely distributed in the human body. They occur in various organs of the...
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Correlation of four-phase CT findings of rectal neuroendocrine neoplasms with different World Health Organization grades
PurposeTo investigate the four-phase computed tomography (CT) features of rectal neuroendocrine neoplasms (R-NENs) as they relate to different World...
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Long-term outcomes of transanal endoscopic microsurgery for the treatment of rectal neuroendocrine tumors
BackgroundTransanal endoscopic microsurgery (TEM) has been accepted worldwide for the treatment of local rectal lesions. We aimed to assess the...
