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Diagnosis of Apis dorsata venom allergy: use of recombinant allergens of Apis mellifera and a passive basophil activation test
BackgroundAllergy to Apis dorsata (Giant Asian Honeybee) venom is the commonest insect allergy in Sri Lanka and South East Asia. However, laboratory...
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The Relationship of Parasite Allergens to Allergic Diseases
Purpose of ReviewHelminth infections modify the natural history of allergic diseases, by either decreasing or increasing their symptoms. Several...
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The Role of Defensins as Pollen and Food Allergens
Purpose of ReviewDefensin-polyproline–linked proteins are relevant allergens in Asteraceae pollen. Depending on their prevalence and amount in the...
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Allergens from house dust and storage mites
House dust mites are among the most important allergy triggers worldwide. While mites of the genus Dermatophagoides occur almost worldwide, the...
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Identification of allergens in coconut milk and oil with patients sensitized to coconut milk in Sri Lanka
BackgroundDespite the low prevalence of IgE sensitivity to fresh or boiled coconut milk and coconut oil, those may contain allergens of which the...
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Impact of oligomerization on the allergenicity of allergens
Type I hypersensitivity (allergic reaction) is an unsuitable or overreactive immune response to an allergen due to cross-link immunoglobulin E (IgE)...
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Evaluation of the local and systemic pattern of sensitization to allergens in patients with adenotonsillar hypertrophy
PurposeAdenotonsillar hypertrophy (ATH) is a medical condition characterized by the enlargement or swelling of the tonsils. The role of allergy in...
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Poultry Meat allergy: a Review of Allergens and Clinical Phenotypes
Purpose of reviewIn the recent years, more cases of poultry meat allergy, both IgE- or non-IgE-mediated, are being reported. Patients have varied...
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Allergens from Edible Insects: Cross-reactivity and Effects of Processing
Purpose of ReviewThe recent introduction of edible insects in Western countries has raised concerns about their safety in terms of allergenic...
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Therapeutic potential of the topical recombinant human interleukin-1 receptor antagonist in guinea pigs with allergic rhinitis
BackgroundRecombinant human Interleukin receptor antagonist (rhIL-Ra) can bind to the IL-1 receptor on the cell membrane and reversibly blocks the...
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Intralymphatic immunotherapy with tyrosine-adsorbed allergens: a double-blind, placebo-controlled trial
BackgroundMost previous studies used aluminum hydroxide-absorbed allergen extracts in evaluating the potential therapeutic roles of intralymphatic...
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Concordance of skin test reactivity between indoor inhalant allergens among children with allergic respiratory disease
BackgroundIn vitro studies have demonstrated cross-reactivity among indoor allergen proteins in children with allergic respiratory diseases. However,...
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Marker allergens in Hymenoptera venom allergy — Characteristics and potential use in precision medicine
BackgroundA comprehensive diagnostic work-up is essential to ensure adequate patient management for the potentially life-threatening condition of...
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Shrimp Extract Exacerbates Allergic Immune Responses in Mice: Implications on Clinical Diagnosis of Shellfish Allergy
Tropomyosin has been identified as the major cross-reactive shellfish allergen, but recent studies showed the presence of other clinically relevant...
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Are Physicochemical Properties Sha** the Allergenic Potency of Plant Allergens?
This review searched for published evidence that could explain how different physicochemical properties impact on the allergenicity of food proteins...
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Variation in IgE binding potencies of seven Artemisia species depending on content of major allergens
BackgroundArtemisia weed pollen allergy is important in the northern hemisphere. While over 350 species of this genus have been recorded, there has...
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How molecular diagnostics help us to correctly identify pet allergies
Simultaneous sensitization to two or more animal species is common and represents a regular diagnostic problem during conventional extract-based...
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IgE reactivity to fish allergens from Pacific cod (Gadus macrocephalus) in atopic dogs
BackgroundIgE reactivity to fish allergens in atopic dogs, which are used as models for food allergy, has not been elucidated to date. We...
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Role of Small Molecule Ligands in IgE-Mediated Allergy
Purpose of ReviewA significant fraction of allergens bind small molecular ligands, and many of these compounds are classified as lipids. However, in...