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Real-world Management of CML: Outcomes and Treatment Patterns
Purpose of ReviewChronic myeloid leukemia (CML) is a disease that previously signified a poor prognosis, but treatment options and outcomes have...
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From real world data to real world evidence to improve outcomes in neuro-ophthalmology
Real-world data (RWD) can be defined as all data generated during routine clinical care. This includes electronic health records, disease-specific...
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Real-World Management of Patients with Pulmonary Arterial Hypertension: Insights from EXPOSURE
IntroductionFurther insights into real-world management and outcomes of patients with pulmonary arterial hypertension (PAH) are needed. This interim...
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The management pattern and outcomes of chronic thromboembolic pulmonary hypertension: rationale and design for a Chinese real-world study
BackgroundChronic thromboembolic pulmonary hypertension (CTEPH) is a progressive pulmonary vascular disorder with substantial morbidity and...
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Real-world experience with Deutetrabenazine management in patients with Huntington’s disease using video-based telemedicine
BackgroundHuntington’s disease (HD) is a rare progressive neurological disorder, and telemedicine has the potential to improve the quality of care...
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Management of Patients Affected by Moderate-to-Severe Atopic Dermatitis with JAK Inhibitors in Real-World Clinical Practice: An Italian Delphi Consensus
IntroductionSeveral systemic therapies have been approved for the treatment of severe AD. In particular, Janus kinase inhibitors (JAKi), including...
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Expert Consensus on Real-World Use and Consumption Patterns of a Fixed-Dose Combination Foam for Psoriasis as a Reactive Management (RM) and Proactive Management (PAM) Regimen
IntroductionPlaque psoriasis is a chronic skin disease characterised by periods of remission and relapse and associated with considerable burden to...
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Real-world effectiveness and safety of stereotactic body radiotherapy for liver metastases with different respiratory motion management techniques
PurposeStereotactic body radiotherapy (SBRT) has been firmly established as a treatment choice for patients with oligometastases, as it has...
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Real-world management of chronic and postprandial hyperkalemia in CKD patients treated with patiromer: a single-center retrospective study
IntroductionHyperkalemia, one of the most important electrolyte abnormalities of chronic kidney disease (CKD), often limits the use of...
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Real-world data on the management of pazopanib-induced liver toxicity in routine care of renal cell cancer and soft tissue sarcoma patients
PurposePazopanib is known to cause liver toxicity. A relationship between pazopanib exposure and alanine transaminase elevations has been described...
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Multi-method study of the implementation of Cognitive Symptom Management and Rehabilitation Training (CogSMART) in real-world settings
Cognitive Symptom Management and Rehabilitation Training (CogSMART) and Compensatory Cognitive Training (CCT) are evidence-based compensatory...
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Ultrasound Surveillance in Melanoma Management: Bridging Diagnostic Promise with Real-World Adherence: A Systematic Review and Meta-Analysis
BackgroundUltrasound surveillance has become the new standard of care in stage III melanoma after the 2017 Multicenter Selective Lymphadenectomy...
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Real-World Frequency and Management of Ocular Adverse Events in Eyes with Neovascular Age-Related Macular Degeneration Treated with Brolucizumab
IntroductionIntraocular inflammation (IOI)-related adverse events (AEs) that may result in severe vision loss have been associated with the...
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Management of Moderate to Severe Plaque Psoriasis with Brodalumab in Daily Practice: Real-World Evidence from the LIBERO Study in the Czech Republic
IntroductionPsoriasis is a chronic, immune-mediated inflammatory skin disease. Despite the availability of several therapies, many patients affected...
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Real-World Evaluation of the Management, Treatment Pathways and Outcome of Melanoma Patients with Target Therapies in Italy
IntroductionIn recent years, an increasing trend in the incidence of melanoma has been observed in Europe. Although early diagnosis and prompt...
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Risk factors and management of gastrointestinal bleeding in patients with or without antiplatelet and anticoagulation therapy: a multicenter real-world prospective study
BackgroundAntiplatelet and anticoagulation drugs complicate acute gastrointestinal bleeding (GIB) patients. Limited data about the risk factors and...
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Development of a real-world database for asthma and COPD: The SingHealth-Duke-NUS-GSK COPD and Asthma Real-World Evidence (SDG-CARE) collaboration
PurposeThe SingHealth-Duke-GlaxoSmithKline COPD and Asthma Real-world Evidence (SDG-CARE) collaboration was formed to accelerate the use of...
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Real-world assessment of effectiveness and safety profile of remogliflozin etabonate in management of type 2 diabetes mellitus
AimTo assess the real-world effectiveness and safety of remogliflozin in the management of type 2 diabetes mellitus (T2DM) in a large uncontrolled...
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Description and management of patients with anal fissure: insights on Italian primary care setting coming from real-world data
To describe patients with anal fissure (AF) and their management in primary care. Retrospective study using the Italian Longitudinal Patient Database...
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ATRAcTR (Authentic Transparent Relevant Accurate Track-Record): a screening tool to assess the potential for real-world data sources to support creation of credible real-world evidence for regulatory decision-making
Adoption and use of real-world data (RWD) for decision-making has been complicated by concerns regarding whether RWD was fit-for-purpose or was of...