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Role of Calcitonin and Strontium Ranelate in Osteoporosis
BackgroundBoth Strontium Ranelate (SR) and Calcitonin (CT) can be used to treat osteoporosis. Calcitonin was actually one of the very initial...
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Cardiovascular safety of calcium, magnesium and strontium: what does the evidence say?
Calcium, magnesium and strontium have all been implicated in both musculoskeletal and cardiovascular health and disease. However, despite these three...
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Osteoporosis Prevention and Management
Osteoporosis, defined by BMD at the hip or lumbar spine that is less than or equal to 2.5 standard deviations below the mean BMD of a young-adult...
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Clinical guidelines for the prevention and treatment of osteoporosis: summary statements and recommendations from the Italian Society for Orthopaedics and Traumatology
BackgroundThe Italian Society for Orthopaedics and Traumatology conceived this guidance—which is primarily addressed to Italian orthopedic surgeons,...
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Increased risk of strontium ranelate-related SJS/TEN is associated with HLA
SummarySevere adverse drug reactions (ADR) of Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) in some patients receiving strontium...
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Effect of osteoporosis medications on fracture healing
Antiosteoporotic medications are often used to concurrently treat a patient’s fragility fractures and underlying osteoporosis. This review evaluates...
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7th drug hypersensitivity meeting: part one
Oral Abstracts
O1 Functionally distinct HMGB1 isoforms correlate with physiological processes in drug-induced SJS/TEN
Daniel F. Carr, Wen-Hung Chung,...
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The calcium-sensing receptor in bone metabolism: from bench to bedside and back
SummaryThe calcium-sensing receptor (CaSR), a key player in the maintenance of calcium homeostasis, can influence bone modeling and remodeling by...
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The Future of Osteoarthritis Therapeutics: Targeted Pharmacological Therapy
Osteoarthritis (OA) is one of the most common forms of degenerative joint disease and a major cause of pain and disability affecting the aging...
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Fracture healing in elderly patients: new challenges for antiosteoporotic drugs
Osteoporosis is a major public health concern, characterized by low bone mass and structural deterioration of bone tissue, leading to bone fragility...
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Drug rash with eosinophilia and systemic symptoms (DRESS) in patients receiving strontium ranelate
SummaryWe have reviewed 47 drug rash with eosinophilia and systemic symptoms (DRESS) cases associated to strontium ranelate reported up to March 2011...
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Alopecia associated with strontium ranelate use in a 62-year-old woman
Strontium ranelate is an effective drug that was developed for treating osteoporosis. Here, we report the case of a 62-year-old woman who developed...
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European guidance for the diagnosis and management of osteoporosis in postmenopausal women
SummaryGuidance is provided in a European setting on the assessment and treatment of postmenopausal women at risk of fractures due to osteoporosis.
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Effective use of strontium-89 in osseous metastases
Bone is one of the organs to which cancer metastasizes most frequently. However, it is not a vital organ, therefore, survival after the occurrence of...
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Spotlight on Strontium Ranelate
This is a review of the pharmacology of strontium ranelate (Protelos®, Protos®, Protaxos®, Bivalos®, Osseor®), and its efficacy and tolerability in...
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Antifracture Efficacy of Currently Available Therapies for Postmenopausal Osteoporosis
Osteoporosis is a systemic bone disease characterized by low bone mass and bone mineral density, and deterioration of the underlying structure of...
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Possible benefits of strontium ranelate in complicated long bone fractures
Osteoporosis drugs are prescribed to prevent fragility fractures, which is the principal aim of the management of osteoporosis. However, if fracture...
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Strontium Ranelate
This is a review of the pharmacology of strontium ranelate (Protelos®, Protos®, Protaxos®, Bivalos®, Osseor®), and its efficacy and tolerability in...
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Anabolic Agents and Bone Quality
BackgroundThe definition of bone quality is evolving particularly from the perspective of anabolic agents that can enhance not only bone mineral...