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1. Impact of RB1 gene screening from blood collected on a single day from 411 family members of 113 Retinoblastoma survivors in India

   Objectives

   To analyse the profile and implication of genetic testing in a cohort of retinoblastoma (RB) patients and their families conducted on a...

   Ayyasamy Vanniarajan, Puja Maitra, ... Parag K. Shah in Eye

   Article 10 February 2024
   

2. RB loss determines selective resistance and novel vulnerabilities in ER-positive breast cancer models

   The management of metastatic estrogen receptor (ER) positive HER2 negative breast cancer (ER+) has improved; however, therapeutic resistance and...

   Vishnu Kumarasamy, Ram Nambiar, ... Erik S. Knudsen in Oncogene

   Article 09 June 2022
   

3. Myocardial perfusion quantification with Rb-82 PET: good interobserver agreement of Carimas software on global, regional, and segmental levels

   Purpose

   To estimate the interobserver agreement of the Carimas software package (SP) on global, regional, and segmental levels for the most widely...

   Sergey V. Nesterov, Emmanuel Deshayes, ... Juhani M. Knuuti in Annals of Nuclear Medicine

   Article Open access 22 February 2022
   

4. Diosmetin suppresses the progression of ESCC by CDK2/Rb/E2F2/RRM2 pathway and synergies with cisplatin

   Cisplatin (CDDP) is the first-line drug in the clinical treatment of esophageal squamous cell carcinoma (ESCC), which has severe nephrotoxicity....

   Yihuan Chen, **aoshuo Dai, ... **g Lu in Oncogene

   Article 22 June 2023
   

5. Family presence during invasive procedures: a pilot study to test a tool

   Background

   Family Presence During Invasive Procedures (FPDI) generates controversy among healthcare professionals. Twibell and her team designed an...

   Eva de Mingo-Fernández, Ángel Belzunegui-Eraso, ... María Jiménez-Herrera in BMC Health Services Research

   Article Open access 26 December 2022

6. ⁸²Rb and [¹⁵O]H₂O myocardial perfusion PET imaging: a prospective head to head comparison

   Background

   ⁸² Rb PET and [ ¹⁵ O]H ₂ O PET are both validated tracers for myocardical perfusion imaging but have not previously been compared clinically....

   Martin Krakauer, Afefah Ismail, ... Lisbeth Marner in Journal of Nuclear Cardiology

   Article Open access 03 October 2023
   

7. Prediction of outcome by ⁸²Rb PET/CT in patients with ischemia and nonobstructive coronary arteries

   Background

   The purpose of this study was to assess the prognostic value of cardiac ⁸² Rb positron emission tomography (PET)/computed tomography (CT)...

   Emilia Zampella, Teresa Mannarino, ... Wanda Acampa in Journal of Nuclear Cardiology

   Article 09 November 2022
   

8. Improved diagnostic accuracy for coronary artery disease detection with quantitative 3D ⁸²Rb PET myocardial perfusion imaging

   Purpose

   To establish requirements for normal databases for quantitative rubidium-82 ( ⁸² Rb) PET MPI analysis with contemporary 3D PET/CT technology...

   Jennifer M. Renaud, Alexis Poitrasson-Rivière, ... Venkatesh L. Murthy in European Journal of Nuclear Medicine and Molecular Imaging

   Article 18 September 2023
   

9. Static CT myocardial perfusion imaging: image quality, artifacts including distribution and diagnostic performance compared to ⁸²Rb PET

   Background

   Rubidium-82 positron emission tomography ( ⁸² Rb PET) MPI is considered a noninvasive reference standard for the assessment of myocardial...

   João R. Inácio, Sriraag Balaji Srinivasan, ... Girish Dwivedi in European Journal of Hybrid Imaging

   Article Open access 04 January 2022
   

10. A novel microdeletion of 517 kb downstream of the PAX6 gene in a Chinese family with congenital aniridia

    Background

    To identify the disease-causing gene in a Chinese family affected with congenital aniridia.

    Methods

    Patients underwent systematic...

    Yinwen Li, Jieqiong Chen, ... **aodong Sun in BMC Ophthalmology

    Article Open access 26 September 2023
    

11. Delineating family needs in the transition from hospital to home for children with medical complexity: part 2, a phenomenological study

    Background

    A systematic literature review on the transition from hospital-to-home (H2H) of families with a child with medical complexity (CMC),...

    L. van de Riet, M. W. Alsem, ... C. D. van Karnebeek in Orphanet Journal of Rare Diseases

    Article Open access 12 December 2023

12. FOXP1 drives osteosarcoma development by repressing P21 and RB transcription downstream of P53

    Osteosarcoma has a poor prognosis, and the poor understanding of the genetic drivers of osteosarcoma hinders further improvement in therapeutic...

    Hanjun Li, **uguo Han, ... Tingting Tang in Oncogene

    Article 14 March 2021
    

13. The sirtuin family in health and disease

    Sirtuins (SIRTs) are nicotine adenine dinucleotide(+)-dependent histone deacetylases regulating critical signaling pathways in prokaryotes and...

    Qi-Jun Wu, Tie-Ning Zhang, ... Yu-Hong Zhao in Signal Transduction and Targeted Therapy

    Article Open access 29 December 2022
    

14. The IL-17 family in diseases: from bench to bedside

    The interleukin-17 (IL-17) family comprises six members (IL-17A–17F), and recently, all of its related receptors have been discovered. IL-17 was...

    Longjie Huangfu, Ruiying Li, ... Shan Wang in Signal Transduction and Targeted Therapy

    Article Open access 11 October 2023
    

15. TAM family kinases as therapeutic targets at the interface of cancer and immunity

    Novel treatment approaches are needed to overcome innate and acquired mechanisms of resistance to current anticancer therapies in cancer cells and...

    Deborah DeRyckere, Justus M. Huelse, ... Douglas K. Graham in Nature Reviews Clinical Oncology

    Article 04 September 2023
    

16. Microarray evidence that 8-cell human embryos express some hormone family members including oxytocin

    Objective

    This study is to discover hormone pathways active in early cleaving human embryos.

    Methods

    A list of 152 hormones and receptors were...

    Amy Lee Harris, Vasiliki Dinopoulou, ... Ann A. Kiessling in Journal of Assisted Reproduction and Genetics

    Article 22 December 2023

17. Peroxisome proliferator-activated receptor gamma coactivator-1 (PGC-1) family in physiological and pathophysiological process and diseases

    Peroxisome proliferator-activated receptor gamma coactivator-1 (PGC-1) family (PGC-1s), consisting of three members encompassing PGC-1α, PGC-1β, and...

    Lu Qian, Yanli Zhu, ... Yang Yang in Signal Transduction and Targeted Therapy

    Article Open access 01 March 2024
    

18. Motivation to Study in a Family Medicine Curriculum (Year 5) at Saarland University

    Background

    A new competency-based blended-learning Family Medicine curriculum was implemented at Saarland University in 2020. Based on...

    Aline Salzmann, Catherine Bopp, ... Fabian Dupont in Zeitschrift für Allgemeinmedizin

    Article 01 April 2022

19. Assessing the mediating role of motivation in the relationship between perceived management support and perceived job satisfaction among family doctors in Jiangsu province, China

    Background

    The study aimed to examine the influence of perceived management support on job satisfaction through the mediating role of motivation among...

    **nglong Xu, Lulin Zhou, ... Prince Ewudzie Quansah in Human Resources for Health

    Article Open access 28 August 2023
    

20. Complete loss of miR-200 family induces EMT associated cellular senescence in gastric cancer

    The EMT (epithelial-to-mesenchymal-transition) subtype of gastric cancer (GC) is associated with poor treatment responses and unfavorable clinical...

    Liang Yu, Can Cao, ... Jikun Li in Oncogene

    Article Open access 19 October 2021