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Mental health disturbance in preclinical medical students and its association with screen time, sleep quality, and depression during the COVID-19 pandemic
BackgroundAffected by various hurdles during COVID-19, preclinical medical students are at an elevated risk for mental health disturbances. However,...
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Introduction to surgery in preclinical years: curriculum development and impact
PurposeExposure to surgery in preclinical years of medical school is traditionally very limited. It is estimated that 59% of students make their...
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Standardization of Point-of-Care-Ultrasonography in Critical Care: Enhancing Quality and Efficiency
Purpose of the ReviewThe integration of point of care ultrasound (POCUS) in the critical care specialty has changed the field's practice. This review...
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Value of preclinical systematic reviews and meta-analyses in pediatric research
AbstractSimilar to systematic reviews (SRs) in clinical fields, preclinical SRs address a specific research area, furnishing information on current...
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Randomized Controlled Trial of Clinical Guidelines Versus Interactive Decision-Support for Improving Medical Trainees’ Confidence with Latent Tuberculosis Care
BackgroundIn order to eliminate tuberculosis (TB) in the USA, primary care providers must take on an expanded role in the diagnosis and management of...
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Point-of-Care-ultrasound in undergraduate medical education: a sco** review of assessment methods
BackgroundPoint-of-Care-Ultrasound (POCUS) curricula have rapidly expanded in undergraduate medical education (UME). However, the assessments used in...
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Accuracy between prehospital and hospital diagnosis in helicopter emergency medical services and its consequences for trauma care
PurposeFor optimal prehospital trauma care, it is essential to adequately recognize potential life-threatening injuries in order to correctly triage...
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Reporting guidelines in medical artificial intelligence: a systematic review and meta-analysis
BackgroundThe field of Artificial Intelligence (AI) holds transformative potential in medicine. However, the lack of universal reporting guidelines...
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MIB Guides: Preclinical Radiopharmaceutical Dosimetry
Preclinical dosimetry is essential for guiding the design of animal radiopharmaceutical biodistribution, imaging, and therapy experiments, evaluating...
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Interobserver variability in preclinical assessment of collision variables following traffic accidents
PurposeTraffic accidents persist as a leading cause of death. European law mandates the integration of automatic emergency call systems (eCall). Our...
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Can current preclinical strategies for radiopharmaceutical development meet the needs of targeted alpha therapy?
Preclinical studies are essential for effectively evaluating TAT radiopharmaceuticals. Given the current suboptimal supply chain of these...
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Development of a smartphone screening test for preclinical Alzheimer’s disease and validation across the dementia continuum
BackgroundDementia prevalence is predicted to triple to 152 million globally by 2050. Alzheimer’s disease (AD) constitutes 70% of cases. There is an...
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Effectiveness of aromatherapy for prevention or treatment of disease, medical or preclinical conditions, and injury: protocol for a systematic review and meta-analysis
BackgroundAromatherapy — the therapeutic use of essential oils from plants (flowers, herbs or trees) to treat ill health and promote physical,...
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Health equity, care access and quality in headache – part 2
BackgroundHeadache disorders are a global public health concern affecting diverse populations. This review examines headache service organizations in...
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Knowledge and attitudes of Italian medical oncologists and palliative care physicians toward medical use of cannabis in cancer care: a national survey
PurposeDespite advances in supportive care, cancer-related symptoms tend to be persistent regardless of cancer type, stage of disease, or treatment...
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“Digital biomarkers” in preclinical heart failure models — a further step towards improved translational research
Innovations in the development of novel heart failure therapies are essential to further increase the predictive value of early research findings....
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Personalizing non-small cell lung cancer treatment through patient-derived xenograft models: preclinical and clinical factors for consideration
PurposeIn the pursuit of creating personalized and more effective treatment strategies for lung cancer patients, Patient-Derived Xenografts (PDXs)...
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Obesity preclinical elective: a qualitative thematic analysis of student feedback
BackgroundEducation about the prevalent chronic disease of obesity is still minimal and variable in medical school curricula. In a student-led effort...
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Focused ultrasound combined with radiotherapy for malignant brain tumor: a preclinical and clinical study
IntroductionBlood–brain barrier (BBB) remains to be the major obstacle to conquer in treating patients with malignant brain tumors. Radiation therapy...
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Chinese Preclinical Alzheimer’s Disease Study (C-PAS): Design and Challenge from PET Acceptance
BackgroundLarge-scale preclinical Alzheimer’s disease study based on β-amyloid positron emission tomography (PET) has not been conducted in China.
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