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Machine learning identifies multi-parametric functional PET/MR imaging cluster to predict radiation resistance in preclinical head and neck cancer models
PurposeTumor hypoxia and other microenvironmental factors are key determinants of treatment resistance. Hypoxia positron emission tomography (PET)...
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A quantitative imaging biomarker for predicting disease-free-survival-associated histologic subgroups in lung adenocarcinoma
ObjectivesClassification of histologic subgroups has significant prognostic value for lung adenocarcinoma patients who undergo surgical resection....
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The Pregnancy and EARly Life study (PEARL) - a longitudinal study to understand how gut microbes contribute to maintaining health during pregnancy and early life
BackgroundThe early life period represents the first step in establishing a beneficial microbial ecosystem, which in turn affects both short and...
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Funktionelle Bildgebung: Translation von Radiomics und künstlicher Intelligenz in die klinische Praxis
BackgroundRadiomics and artificial intelligence (AI) are among the most important topics in radiologic research of recent years. However, translation...
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A validated RP-UPLC method for estimation of Samidorphan and Olanzapine in mixed powder and combined tablets
Back groundThe key objective of the research study is to develop a new stability-indicating RP-UPLC approach to determine the presence of Samidorphan...
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The relevance of CT-based geometric and radiomics analysis of whole liver tumor burden to predict survival of patients with metastatic colorectal cancer
ObjectivesTo investigate the prediction of 1-year survival (1-YS) in patients with metastatic colorectal cancer with use of a systematic comparative...
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Impact of Arterial Input Function and Pharmacokinetic Models on DCE-MRI Biomarkers for Detection of Vascular Effect Induced by Stroma-Directed Drug in an Orthotopic Mouse Model of Pancreatic Cancer
PurposeWe demonstrated earlier in mouse models of pancreatic ductal adenocarcinoma (PDA) that K trans derived from dynamic contrast-enhanced (DCE)...
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Harmonization of radiomic feature distributions: impact on classification of hepatic tissue in CT imaging
ObjectivesFollowing the craze for radiomic features (RF), their lack of reliability raised the question of the generalizability of classification...
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Incorporating radiomics into clinical trials: expert consensus endorsed by the European Society of Radiology on considerations for data-driven compared to biologically driven quantitative biomarkers
AbstractExisting quantitative imaging biomarkers (QIBs) are associated with known biological tissue characteristics and follow a well-understood path...
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Reproducibility of hepatic MR elastography across field strengths, pulse sequences, scan intervals, and readers
PurposeTo evaluate the reproducibility of hepatic MRE under various combinations of settings of field strength, pulse sequence, scan interval, and...
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Standardised lesion segmentation for imaging biomarker quantitation: a consensus recommendation from ESR and EORTC
BackgroundLesion/tissue segmentation on digital medical images enables biomarker extraction, image-guided therapy delivery, treatment response...
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A new stability indicating RP-UPLC method for simultaneous estimation of Doravirine, Lamivudine and Tenofovir disoproxil fumarate in bulk and their combined pharmaceutical formulation
BackgroundTo establish a simple, sensitive, accurate, precise, efficient, economical RP-UPLC method for simultaneous estimation of Doravirine,...
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Assessing the quality of cardiac rehabilitation programs by measuring adherence to the Australian quality indicators
BackgroundEvery year, over 65,000 Australians experience an acute coronary syndrome (ACS) and around one-third occur in people with prior coronary...
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Repeatability and reproducibility of ADC measurements: a prospective multicenter whole-body-MRI study
ObjectivesMulticenter oncology trials increasingly include MRI examinations with apparent diffusion coefficient (ADC) quantification for lesion...
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Basic concept and clinical applications of quantitative ultrasound (QUS) technologies
In the field of clinical ultrasound, the full digitalization of diagnostic equipment in the 2000s enabled the technological development of...
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Liver fat quantification: where do we stand?
Excessive intracellular accumulation of triglycerides in the liver, or hepatic steatosis, is a highly prevalent condition affecting approximately one...
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An effective stability indicating RP-HPLC method for simultaneous estimation of Dolutegravir and Lamivudine in bulk and their tablet dosage form
BackgroundA Simple, sensitive, and specific stability indicating reverse phase HPLC method was developed for simultaneous estimation of Lamivudine...
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Psychometric Properties of the General Organizational Index (GOI): A Measure of Individualization and Quality Improvement to Complement Program Fidelity
To assess the implementation of effective practices, mental health programs need standardized measures. The General Organizational Index (GOI),...
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Diffusion-weighted imaging of the breast—a consensus and mission statement from the EUSOBI International Breast Diffusion-Weighted Imaging working group
AbstractThe European Society of Breast Radiology (EUSOBI) established an International Breast DWI working group. The working group consists of...