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The pupil and myself: pupil dilation during retrieval of self-defining memories
BackgroundThere is a recent interest in pupil dilation during the retrieval of autobiographical memory. We pursued this line of research by measuring...
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Altered pupil responses to social and non-social stimuli in Shank3 mutant dogs
Pupillary response, an important process in visual perception and social and emotional cognition, has been widely studied for understanding the...
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The pupil constriction to light is associated with cognitive measures in middle-aged and older adults
AimsThe evidence relating the pupil light reflex (PLR) and cognition have been inconsistent. In this cross-sectional study, we evaluated the...
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Neurological Pupil Index and Delayed Cerebral Ischemia after Subarachnoid Hemorrhage: A Retrospective Multicentric Study
BackgroundDelayed cerebral ischemia (DCI) occurs in around 30% of patients suffering from nontraumatic subarachnoid hemorrhage (SAH) and is...
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Behavioral and brain reactivity to uncertain stress prospectively predicts binge drinking in youth
Prior studies show that individuals with alcohol use disorder exhibit exaggerated behavioral and brain reactivity to uncertain threats (U-threat). It...
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The impact of sedative and vasopressor agents on cerebrovascular reactivity in severe traumatic brain injury
BackgroundThe aim of this study is to evaluate the impact of commonly administered sedatives (Propofol, Alfentanil, Fentanyl, and Midazolam) and...
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Statistical properties of cerebral near infrared and intracranial pressure-based cerebrovascular reactivity metrics in moderate and severe neural injury: a machine learning and time-series analysis
BackgroundCerebrovascular reactivity has been identified as a key contributor to secondary injury following traumatic brain injury (TBI). Prevalent...
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Dynamic assessment of variations in pupil diameter using swept-source anterior segment optical coherence tomography after phakic collamer lens implantation
PurposeTo dynamically assess variations in pupil diameter induced by changes in brightness in myopic eyes implanted with an implantable collamer lens...
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Association between cerebrovascular reactivity in adult traumatic brain injury and improvement in patient outcome over time: an exploratory analysis
BackgroundImpaired cerebrovascular reactivity following moderate/severe traumatic brain injury (TBI) has emerged as a key potential driver of...
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A comprehensive systematic review and meta-analysis study in comparing decompressive craniectomy versus craniotomy in patients with acute subdural hematoma
There are two controversial surgery methods which are traditionally used: craniotomy and decompressive craniectomy. The aim of this study was to...
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A differential of the left eye and right eye neurological pupil index is associated with discharge modified Rankin scores in neurologically injured patients
BackgroundAutomated infrared pupillometry (AIP) and the Neurological Pupil index (NPi) provide an objective means of assessing and trending the...
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Cerebrovascular pressure reactivity and brain tissue oxygen monitoring provide complementary information regarding the lower and upper limits of cerebral blood flow control in traumatic brain injury: a CAnadian High Resolution-TBI (CAHR-TBI) cohort study
BackgroundBrain tissue oxygen tension (PbtO 2 ) and cerebrovascular pressure reactivity monitoring have emerged as potential modalities to...
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Cerebral autoregulation in traumatic brain injury: ultra-low-frequency pressure reactivity index and intracranial pressure across age groups
BackgroundThe ultra-low-frequency pressure reactivity index (UL-PRx) has been established as a surrogate method for bedside estimation of cerebral...
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Prognostic value of near-infrared spectroscopy regional oxygen saturation and cerebrovascular reactivity index in acute traumatic neural injury: a CAnadian High-Resolution Traumatic Brain Injury (CAHR-TBI) Cohort Study
BackgroundNear-infrared spectroscopy regional cerebral oxygen saturation (rSO 2 ) has gained interest as a raw parameter and as a basis for measuring...
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Anisocoria After Direct Light Stimulus is Associated with Poor Outcomes Following Acute Brain Injury
BackgroundAssessing pupil size and reactivity is the standard of care in neurocritically ill patients. Anisocoria observed in critically ill patients...
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The use of quantitative pupillometry in brain death determination: preliminary findings
PurposeQuantitative pupillometry (QP) has been increasingly applied in neurocritical care as an easy-to-use and reliable technique for evaluating the...
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The Optimal pressure reactivity index range is disease-specific: A comparison between aneurysmal subarachnoid hemorrhage and traumatic brain injury
PurposeImpaired cerebral pressure autoregulation is common and detrimental after acute brain injuries. Based on the prevalence of delayed cerebral...
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Abnormal neurological pupil index is associated with malignant cerebral edema after mechanical thrombectomy in large vessel occlusion patients
Background and objectivesMalignant cerebral edema (MCE) is a feared complication in patients suffering from large vessel occlusion. Variables...
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Unilateral Urrets-Zavalia syndrome after Implantable Collamer Lens implantation: a case report and review of the literature
BackgroundFixed dilated pupil after ophthalmic surgery or Urrets-Zavalia syndrome occurs after anterior segment surgery and usually relates to...
