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Application of direct analysis in real-time mass spectrometry (DART-MS) in forensic science: a comprehensive review
BackgroundAs the rate of crime is constantly increasing, the workload on the forensic analyst also piles up. The availability of a limited number of...
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The application of PTR-MS and non-targeted analysis to characterize VOCs emitted from a plastic recycling facility fire
BackgroundOn April 11th, 2023, the My Way Trading (MWT) recycling facility in Richmond, Indiana caught fire, mandating the evacuation of local...
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Analytical characterization and differentiation between threo- and erythro-4-fluoroethylphenidate
PurposeMethylphenidate analogs appeared on the drug market during the last years. Its analogs contain two chiral centers and, thus, have potential...
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Identification of hexahydrocannabinol (HHC), dihydro-iso-tetrahydrocannabinol (dihydro-iso-THC) and hexahydrocannabiphorol (HHCP) in electronic cigarette cartridge products
PurposeSince 2021, products claiming to contain hexahydrocannabinol (HHC) and hexahydrocannabiphorol (HHCP), which are tetrahydrocannabinol (THC)...
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Cajanus cajan induces mitochondrial-mediated apoptosis via caspase activation and cytochrome c release
BackgroundAttention has recently focused on mitochondrial-mediated apoptosis as a signaling pathway that is disrupted in many diseases involving...
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A chronological study of gunshot residue (GSR) detection techniques: a narrative review
BackgroundThe investigation and reconstruction of firearm-related crimes for the determination of the shooting distance, time since fire, and gunshot...
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Integrative metabolomic profiling reveals aberrations in myometrium associated with adenomyosis: a pilot study
BackgroundUterine adenomyosis is a common gynecologic disease in premenopausal women, the pathological mechanism of which remains largely unknown....
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Cyclotron production and radiochemical purification of terbium-155 for SPECT imaging
BackgroundTerbium-155 [T 1/2 = 5.32 d, Eγ = 87 keV (32%) 105 keV (25%)] is an interesting radionuclide suitable for single photon emission computed...
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Decoction regulating phytochemicals’ micromorphology changes and anti-inflammation activity enhancements originated from herb medicine supermolecules
BackgroundMahuang Fuzi decoction (MGF) is composed of three herb medicines that has been clinically used to treat inflammatory diseases for a long...
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Ubiquitin ligase subunit FBXO9 inhibits V-ATPase assembly and impedes lung cancer metastasis
BackgroundThe evolutionarily conserved protein FBXO9 acts as a substrate receptor for the SKP1-cullin-1-RBX1 ubiquitin ligase and is implicated in...
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Circulating metabolites modulated by diet are associated with depression
Metabolome reflects the interplay of genome and exposome at molecular level and thus can provide deep insights into the pathogenesis of a complex...
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Determination of 3- and 4-chloromethcathinone interactions with plasma proteins: study involving analytical and theoretical methods
PurposeThe purpose of this paper was to determine 3- and 4-chloromethcathinone (3- and 4-CMC) binding degree and possible binding interaction modes...
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Gut-Brain-axis: effect of basil oil on the gut microbiota and its contribution to the anticonvulsant properties
BackgroundEpilepsy is a chronic neurological condition that disrupts the normal functioning of the brain and it is characterized by seizures....
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A cross-sectional study: a breathomics based pulmonary tuberculosis detection method
BackgroundDiagnostics for pulmonary tuberculosis (PTB) are usually inaccurate, expensive, or complicated. The breathomics-based method may be an...
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Recent progress in the chemical attribution of chemical warfare agents and highly toxic organophosphorus pesticides
PurposeThis paper reviews the background of the development of chemical attribution technology, and discusses analytical and chemometrics...
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A novel set of volatile urinary biomarkers for late-life major depressive and anxiety disorders upon the progression of frailty: a pilot study
Mood and anxiety disorders are frequent in the elderly and increase the risk of frailty. This study aimed to identify novel biomarkers of major...
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Cutting edge rare earth radiometals: prospects for cancer theranostics
BackgroundWith recent advances in novel approaches to cancer therapy and imaging, the application of theranostic techniques in personalised medicine...
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Arsenic alters nitric oxide signaling similar to autism spectrum disorder and Alzheimer’s disease-associated mutations
Epidemiological studies have proven that exposure to Arsenic (AS) leads to the development of many neurological disorders. However, few studies have...
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Fast and noninvasive electronic nose for sniffing out COVID-19 based on exhaled breath-print recognition
The reverse transcription-quantitative polymerase chain reaction (RT-qPCR) approach has been widely used to detect the severe acute respiratory...
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Does the last 20 years paradigm of clinical research using volatile organic compounds to non-invasively diagnose cancer need to change? Challenges and future direction
PurposeVolatile organic compounds (VOCs) have shown great potential as novel biomarkers for cancer detection; however, comprehensive quantitative...
