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Position statement on infection screening, prophylaxis, and vaccination in pediatric patients with rheumatic diseases and immunosuppressive therapies, part 2: infection prophylaxis
This study aims to provide practical recommendations on prophylaxis for infection in pediatric patients with immune-mediated rheumatic diseases...
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Infective Endocarditis Antibiotic Prophylaxis: Review of the Evidence and Guidelines
Purpose of ReviewThe question of antibiotic prophylaxis and its role in prevention of infective endocarditis (IE) remains controversial, with...
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Self-reported prescribing behaviour of vitamin D prophylaxis in healthy children by Belgian paediatricians
There is currently no consensus on the guidelines for vitamin D prophylaxis in healthy children. The purpose of this study was to investigate the...
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Evaluation of venous thromboembolism prophylaxis protocol in hematopoietic cell transplant patients
Hematopoietic cell transplant (HCT) recipients are at risk for thromboembolic and bleeding complications. There is limited evidence regarding the...
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Continuous Antibiotic Prophylaxis in Infants with Grade III, IV, or V Vesicoureteral Reflux
In this multicentric, open label, randomized trial performed across 39 European centers, the investigators randomly assigned infants 1 to 5 months of...
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Cost-Effectiveness Analysis of Pharmacokinetic-Guided Prophylaxis Versus Standard Prophylaxis in Adults with Severe Hemophilia A in China
IntroductionMultiple studies have demonstrated the effectiveness of pharmacokinetic (PK)-guided individualized prophylaxis with human coagulation...
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Prophylaxis and Treatment of Bacterial Infections in Cirrhosis
Purpose of ReviewWe aim to succinctly summarize key clinical management principles in commonly encountered clinical scenarios with regard to...
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Intermittend pneumatic venous thrombembolism (VTE) prophylaxis during neurosurgical procedures
BackgroundThe management of perioperative venous thrombembolism (VTE) prophylaxis is highly variable between neurosurgical departments and general...
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The role of antimicrobial prophylaxis in laparoscopic nephrectomy for renal cell carcinoma
BackgroundTo investigate the role of antimicrobial prophylaxis in laparoscopic nephrectomy for renal cell carcinoma.
MethodsWe retrospectively...
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A systematic review of venous thromboembolism mechanical prophylaxis devices during surgery
PurposeHospitalisation and surgery are major risk factors for venous thromboembolism (VTE). Intermittent pneumatic compression (IPC) and graduated...
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Use of Methenamine for Urinary Tract Infection Prophylaxis: Systematic Review of Recent Evidence
Introduction and HypothesisAntibiotic resistance is an unavoidable consequence of antibiotic use and growing rates of resistance are an urgent issue....
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Venous thromboembolism and bleeding after hepatectomy: role and impact of risk adjusted prophylaxis
Venous thromboembolism (VTE) occurs in 2–6% of post-hepatectomy patients and is associated with increased mortality and morbidity. The use of VTE...
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Outcomes of allogeneic hematopoietic cell transplantation under letermovir prophylaxis for cytomegalovirus infection
Cytomegalovirus (CMV) infection is a major infectious complication following allogeneic hematopoietic cell transplantation (allo-HCT). Although...
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Gram-negative bacterial colonizations before bilateral lung transplant. The impact of ‘targeted’ versus ‘standard’ surgical prophylaxis
BackgroundInfections are one of the most common causes of death after lung transplant (LT). However, the benefit of ‘targeted’ prophylaxis in LT...
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Analysis of HIV drug prophylaxis services cascade in healthcare workers: a cross-sectional study in China
BackgroundHuman immunodeficiency virus (HIV) drug prophylaxis, including post-exposure prophylaxis (PEP) and pre-exposure prophylaxis (PrEP), has not...
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Cytomegalovirus breakthrough and resistance during letermovir prophylaxis
Letermovir is a relatively new antiviral for prophylaxis against cytomegalovirus (CMV) after allogeneic hematopoietic cell transplantation (HCT)....
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Effect of Iron Polymaltose Complex Prophylaxis on Frequency of Iron Deficiency and Iron Deficiency Anemia
ObjectivesTo evaluate the effectiveness of national iron prophylaxis policy in 9–12 mo-old infants in Turkey.
MethodsThis study was planned as a...
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Literature Review: Venous Thromboembolism Prophylaxis in Plastic Surgery
Venous thromboembolism (VTE) is a postoperative complication experienced in all branches of surgery, including plastic surgery. Its occurrence can be...
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Prophylaxis of hepatic encephalopathy: current and future drug targets
Hepatic encephalopathy is described by a broad spectrum of neurological and psychiatric aberrations resulting due to advanced liver dysfunction. It...
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Recent updates on central nervous system prophylaxis in patients with high-risk diffuse large B-cell lymphoma
The use of central nervous system (CNS) prophylaxis for patients with diffuse large B-cell lymphoma (DLBCL) remains controversial. Although uncommon,...