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Incidence Rate and Risk Factors of Probable Sarcopenia: A Comprehensive Analysis
While the factors contributing to probable sarcopenia are not well understood, its prevention is more important than addressing full-blown...
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24-Hour Blood Pressure Variability Via Ambulatory Monitoring and Risk for Probable Dementia in the SPRINT Trial
BackgroundBlood pressure variability is an emerging risk factor for dementia, independent and oftentimes beyond mean blood pressure levels. Recent...
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Usefulness of the skin-wrinkling test in a patient with probable small fiber neuropathy and Gaucher disease
BackgroundGaucher disease (GD) is an autosomal recessive disease characterized by an inborn metabolic error. Although pain attributed to skeletal...
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Resting-state network connectivity changes in drug-naive Parkinson’s disease patients with probable REM sleep behavior disorder
Epidemiological studies have shown that Parkinson’s disease (PD) patients with probable REM sleep behavior disorder (pRBD) present an increased risk...
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Combining semi-quantitative rating and automated brain volumetry in MRI evaluation of patients with probable behavioural variant of fronto-temporal dementia: an added value for clinical practise?
PurposeTo evaluate the diagnostic value of combined semiquantitative and quantitative assessment of brain atrophy in the diagnostic workup of the...
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Sex differences in brain atrophy and cognitive impairment in Parkinson’s disease patients with and without probable rapid eye movement sleep behavior disorder
BackgroundThe presence of rapid eye movement sleep behavior disorder (RBD) contributes to increase cognitive impairment and brain atrophy in...
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A Phase II, Single-Center, Randomized, Double-Blind, Placebo-Controlled Study of the Safety and Therapeutic Efficacy of Intranasal Glulisine in Amnestic Mild Cognitive Impairment and Probable Mild Alzheimer’s Disease
BackgroundIntranasal insulin is a potential treatment for neurodegenerative disease shown to increase cerebral glucose uptake, reduce amyloid...
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Cognitive and psychological characteristics in patients with Cerebral Amyloid Angiopathy: a literature review
AimTo review the current data on cognitive and psychological characteristics of patients with CAA and on the instruments used for their evaluation.
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Adjacent digit fingerprint white line count differences: a pointer to sexual dimorphism for forensic application
BackgroundSex determination is one of the leading criterion in identification and verification of an individual. However, the potential roles of...
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Central Auditory Processing Skills in Individuals with Takayasu Syndrome
The current study was done to assess the central auditory processing in individuals with Takayasu’s Syndrome. The Takayasu Syndrome is a rare...
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Differential associations of clinical features with cerebrospinal fluid biomarkers in dementia with Lewy bodies and Alzheimer’s disease
AimTo explore associations of cerebrospinal fluid biomarkers of neurodegeneration and amyloidosis with caregiver burden, cognition and functionality...
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Identifying dementia using medical data linkage in a longitudinal cohort study: Lothian Birth Cohort 1936
BackgroundThe Lothian Birth Cohort 1936 (LBC1936) is a longitudinal study of ageing with well-characterised assessments, but until now, it has relied...
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“Won’t get fooled again”: statistical fault detection in COVID-19 Latin American data
BackgroundClaims of inconsistency in epidemiological data have emerged for both developed and develo** countries during the COVID-19 pandemic.
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Utility of Environmental Complexity as a Predictor of Alzheimer’s Disease Diagnosis: A Big-Data Machine Learning Approach
BackgroundRural-urban differences and spatial navigation deficits have received much attention in Alzheimer’s Disease research. While individual...
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The efficacy and safety of zolpidem and zopiclone to treat insomnia in Alzheimer’s disease: a randomized, triple-blind, placebo-controlled trial
No prior studies have evaluated the efficacy and safety of zolpidem and zopiclone to treat insomnia of demented patients. This randomized,...
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The burden of headache disorders in the adult general population of the Kingdom of Saudi Arabia: estimates from a cross-sectional population-based study including a health-care needs assessment
BackgroundWe have previously shown headache to be highly prevalent among adults in Saudi Arabia. Here we estimate associated symptom burden and...
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Pairwise association of upper extremity musculoskeletal conditions: large population investigation from PERSIAN cohort study
BackgroundPeople with one area of upper extremity musculoskeletal conditions (UEMSCs) may have other. We aim to determine how frequent is the...
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Effect of COVID-19 on peripheral and central hearing abilities
BackgroundCOVID-19 has caused various implications on physical and mental health of human beings. It included several symptoms involving the auditory...
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Use of outpatient and inpatient health care services by occupation—a register study of employees in Oulu, Finland
BackgroundThe aim of this study was to examine how the use of outpatient and inpatient health services differs by occupational groups, and whether...
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Is there a spinal tap responder in progressive supranuclear palsy? The first prospective study
ObjectiveProgressive supranuclear palsy (PSP) is a progressive neurodegenerative disease, and sometimes shows idiopathic normal pressure...