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Adjusting conventional FRAX estimates of fracture probability according to the number of prior fractures
SummaryThe risk of a recurrent fragility fracture is high following a first fracture and higher still with more than one prior fracture. This study...
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Adjusting conventional FRAX estimates of fracture probability according to the number of prior falls in the preceding year
SummaryA greater propensity to falling is associated with higher fracture risk. This study provides adjustments to FRAX-based fracture probabilities...
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Meta-analysis of probability estimates of worldwide variation of CYP2D6 and CYP2C19
Extensive migration has led to the necessity of knowledge regarding the treatment of migrants with different ethnical backgrounds. This is especially...
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Prioritizing a high posterior probability threshold leading to low error rate over high classification accuracy: the validity of MorphoPASSE software for cranial morphological sex estimation in a contemporary population
An increasing number of software tools can be used in forensic anthropology to estimate a biological profile, but further studies in other...
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Combined use of Donepezil and Memantine increases the probability of five-year survival of Alzheimer’s disease patients
BackgroundAlzheimer’s disease (AD) is the most common neurodegenerative disease. Studying the effects of drug treatments on multiple health outcomes...
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Bedaquiline resistance probability to guide treatment decision making for rifampicin-resistant tuberculosis: insights from a qualitative study
BackgroundBedaquiline (BDQ) is a core drug for rifampicin-resistant tuberculosis (RR-TB) treatment. Accurate prediction of a BDQ-resistant phenotype...
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Assessing the properties of patient-specific treatment effect estimates from causal forest algorithms under essential heterogeneity
BackgroundTreatment variation from observational data has been used to estimate patient-specific treatment effects. Causal Forest Algorithms (CFAs) ...
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The PROMIS-16 reproduces the PROMIS-29 physical and mental health summary scores accurately in a probability-based internet panel
PurposeThe Patient-Reported Outcomes Measurement Information System® (PROMIS)-16 assesses the same multi-item domains but does not include the pain...
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Aspartame exposures in the US population: Demonstration of a novel approach for exposure estimates to food additives using NHANES data
BackgroundExposure to food additives is widespread but up-to-date and accurate intake estimates are rarely available. The safety of the food additive...
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Adjusting conventional FRAX estimates of fracture probability according to the recency of sentinel fractures
SummaryThe risk of a recurrent fragility fracture is particularly high immediately following the fracture. This study provides adjustments to...
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Classification performance of the Sella-Tunis et al. (2017) sex estimation method in Czech population: different posterior probability threshold approaches
In this study we tested classification performance of a sex estimation method from the mandible originally developed by Sella-Tunis et al. (2017) on...
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Systematic Review: Polysubstance Prevalence Estimates Reported during Pregnancy, US, 2009–2020
IntroductionThe objective of this systematic review is to describe polysubstance studies and their prevalence estimates among pregnant people in the...
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Matching on propensity and prognostic scores can lead to different estimates of heterogeneous treatment effects: a case study and simulation
The purpose of this study is to illustrate how matching approaches based on different balancing scores lead to variations in the treatment effect...
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Discrepancies in prevalence estimates of suicidal ideation and attempts in 18- to 22-year-old US college students: a comparison of three surveys
PurposeSuicidal thoughts and behaviors (STB) have been increasing among US college students. Accurate measurement of STB is key to understanding...
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Changes in the probability of hysterectomy in the city of Mainz and Mainz-Bingen region, Germany
BackgroundTo assess the hysterectomy probability by calendar period and age, the overall and the age-specific prevalence of hysterectomy in women...
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Demographic Indicators of Probability Models
Abstract —Describing mortality dynamics using average indicators without considering variability can yield average results, impeding the analysis of...
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A Clinical Decision Tool to Calculate Pretest Probability of Sentinel Lymph Node Metastasis in Primary Cutaneous Melanoma
BackgroundAlthough sentinel lymph node biopsy (SLNB) status is a strong prognostic indicator for cutaneous melanoma, unnecessary SLNBs have...
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Subnational estimates of life expectancy at birth in India: evidence from NFHS and SRS data
BackgroundMortality estimates at the subnational level are of urgent need in India for the formulation of policies and programmes at the district...
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Population Pharmacokinetics and Probability of Target Attainment Analysis of Nadroparin in Different Stages of COVID-19
Background and ObjectiveThe risk of thrombotic complications in critical patients with COVID-19 remains extremely high, and multicenter trials failed...
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Meta-analysis of preclinical measures of efficacy in immune checkpoint blockade therapies and comparison to clinical efficacy estimates
BackgroundDespite the successes of checkpoint inhibitors targeting T-cell receptors, clinical efficacy is highly cancer-dependent and subject to high...
