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Intramedullary spinal cord tumors in pediatric patients presenting later with brain lesions: case series and systematic review of the literature
PurposeIntramedullary spinal cord tumors are an uncommon pathology in adults and children. Most descriptive studies of intramedullary spinal cord...
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Sequencing of cerebrospinal fluid cell-free DNA facilitated early differential diagnosis of intramedullary spinal cord tumors
Pre-surgery differential diagnosis is valuable for personalized treatment planning in intramedullary spinal cord tumors. This study assessed the...
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Neurosurgical emergencies in spinal tumors: pathophysiology and clinical management
Whether they are spinal metastases or primary spinal neoplasms, spinal tumors cause a myriad of complications given their critical location. Spinal...
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Effect of race, sex, and socioeconomic factors on overall survival following the resection of intramedullary spinal cord tumors
IntroductionIntramedullary spinal cord tumors (IMSCTs) account for 2–4% of all primary CNS tumors. Given their low prevalence and the intricacy of...
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Impact of multimodal intraoperative neurophysiological monitoring of the spinal cord during spine and spinal cord surgeries
BackgroundThere is growing evidence of the valuable role of multimodal intraoperative neurophysiological monitoring (IONM) during spine and spinal...
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Characterization and Treatment of Spinal Tumors
The prevalence of spinal tumors is rare in comparison to brain tumors which encompass most central nervous system tumors. Tumors of the spine can be...
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The evolution of spinal cord surgery: history, people, instruments, and results
IntroductionSpinal cord surgery has and always will be a challenging operation with satisfying results, but also with potentially devastating...
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Dorsal column map** in resection of intramedullary spinal cord tumors: a prospective comparison of two methods and neurological follow-up
PurposeIn surgery for intramedullary spinal cord tumors (imSCT), distortion of the anatomy challenges the visual identification of dorsal columns...
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Association of spinal cord abnormalities with vertebral anomalies: an embryological perspective
PurposeTo analyze the relationship between spinal cord and vertebral abnormalities from the point of view of embryology.
MethodsWe analyzed the...
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Pediatric spinal cord diffuse midline glioma with H3 K27M-alteration with leptomeningeal dissemination: a rare case with intracranial hypertension onset and no spinal cord-related symptom
PurposeSpinal cord diffuse midline glioma (DMG) with H3 K27-alteration is a group of spinal cord high-grade glioma with poor outcome. We present a...
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Natural history of spinal cord metastasis from brain glioblastomas
Background and ObjectivesSpinal cord metastasis arising from an intracranial glioblastoma is a rare and late event during the natural course of the...
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Differential target multiplexed spinal cord stimulation using a paddle-type lead placed at the appropriate site for neuropathic pain after spinal cord injury in patients with past spinal surgical histories: study protocol for an exploratory clinical trial
BackgroundNeuropathic pain after spinal cord injury (SCI), both traumatic and non-traumatic, is refractory to various treatments. Spinal cord...
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Neurologic outcomes for adult spinal cord ependymomas stratified by tumor location: a retrospective cohort study and 2-year outlook
Determine whether craniocaudal spinal cord tumor location affects long-term neurologic outcomes in adults diagnosed with spinal ependymomas (SE). A...
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Impact of tumor-associated syrinx on outcomes following resection of primary ependymomas of the spinal cord
PurposeTo interrogate the association of tumor-associated syrinxes with postoperative neurological and oncological outcomes in patients surgically...
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Cervical intramedullary spinal cord metastasis from esophageal adenocarcinoma: a case report
BackgroundIntramedullary spinal cord metastasis (ISCM) is a rare pathologic entity. To the best of our knowledge, this is the second case of ISCM due...
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Diffuse Midline H3K27-Altered Gliomas in the Spinal Cord: A Systematic Review
PurposeTo systematically review the clinical features, management, and outcomes of diffuse midline H3K27-altered gliomas of the spinal cord (DMG-SCs).
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Transcriptomic and epigenetic dissection of spinal ependymoma (SP-EPN) identifies clinically relevant subtypes enriched for tumors with and without NF2 mutation
Ependymomas encompass multiple clinically relevant tumor types based on localization and molecular profiles. Tumors of the methylation class “spinal...
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Spinal cord anomalies in children with anorectal malformations: a retrospective cohort study
PurposeFirst, to assess the number of spinal cord anomalies (SCA), specifically tethered spinal cord (TSC) in patients with anorectal malformations...
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Correlation of bilateral M1 hand area excitability and overall functional recovery after spinal cord injury: protocol for a prospective cohort study
BackgroundAfter spinal cord injury (SCI), a large number of survivors suffer from severe motor dysfunction (MD). Although the injury site is in the...
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Postoperative survival after lumbar instrumented surgery for metastatic spinal tumors: a nationwide population-based cohort analysis
BackgroundIt is difficult to predict the expected survival after lumbar instrumented surgery for metastases owing to the difference among different...
