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Micronutrients in early life and offspring metabolic health programming: a promising target for preventing non-communicable diseases
Chronic non-communicable diseases are the leading cause of morbidity and mortality worldwide. Develo** and implementing effective preventive...
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Pancreatic GLUT2 protein expression and isolated islets insulin secretion decreased in high-fat fed rat dams
PurposeChronic consumption of high-fat foods during the reproductive period may endanger the dams’ metabolic homeostasis and might adversely affect...
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Programming of metabolism by adipokines during development
The intrauterine and early postnatal periods represent key developmental stages in which an organism is highly susceptible to being permanently...
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A Low Dose of Ouabain Alters the Metabolic Profile of Adult Rats Experiencing Intrauterine Growth Restriction in a Sex-Specific Manner
Intrauterine growth restriction (IUGR) increases the risk of type 2 diabetes mellitus (T2DM) and metabolic diseases. The pancreas of fetuses with...
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Obesity in prenatal medicine: a game changer?
Obesity is recognized by the World Health Organization (WHO) as a disease in its own right. Moreover, obesity is an increasingly concerning public...
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The Influences of Perinatal Androgenic Exposure on Cardiovascular and Metabolic Disease of Offspring of PCOS
Hyperandrogenism is an endocrine disorder affecting a large population of reproductive-aged women, thus proportionally high number of fetuses are...
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Epigenetic programming for obesity and noncommunicable disease: From womb to tomb
Several epidemiological, clinical and experimental studies in recent decades have shown the relationship between exposure to stressors during...
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Developmental Programming in Animal Models: Critical Evidence of Current Environmental Negative Changes
The Developmental Origins of Health and Disease (DOHaD) approach answers questions surrounding the early events suffered by the mother during...
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Potential Micronutrient Deficiencies in the First 1000 Days of Life: The Pediatrician on the Side of the Weakest
Purpose of ReviewThis study is to examine potential micronutrient deficiencies and any need for supplementation in children following specific diet...
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Curtailing PCOS
Polycystic ovary syndrome (PCOS), characterized by hormonal imbalance and ovarian dysfunction, often starts during adolescence. Inconsistent...
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