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Insulin Use During Gestational and Pre-existing Diabetes in Pregnancy: A Systematic Review of Study Design
IntroductionInsulin is the first-line pharmacologic therapy for women with diabetes in pregnancy. However, conducting well-designed randomized...
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Supporting self-management in women with pre-existing diabetes in pregnancy: a mixed-methods sequential comparative case study
IntroductionMaternal glycemia is associated with pregnancy outcomes. Thus, supporting the self-management experiences and preferences of pregnant...
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Pre-existing, Concurrent/Early-Onset, and Late-Onset Diabetes in Chronic Pancreatitis: Do Outcomes Differ?
Background/AimsDiabetes secondary to endocrine insufficiency in chronic pancreatitis (CP) may develop at any time during the disease course. We...
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Understanding the self-management experiences and support needs during pregnancy among women with pre-existing diabetes: a qualitative descriptive study
BackgroundWith the increasing prevalence of pre-existing type 1 and type 2 diabetes in pregnancy and their associated perinatal risks, there is a...
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Coexistence of diabetes mellitus and pre-existing cardiovascular disease and mortality in Chinese patients on peritoneal dialysis
BackgroundLittle is known about the association between the coexistence of diabetes mellitus (DM) and pre-existing cardiovascular disease (CVD) and...
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Effects of cardiovascular risk factors and pre-existing diseases on the short-term outcome of Takotsubo syndrome
BackgroundThe effects of cardiovascular risk factors (CVRF) on the development of most acute cardiac conditions are well established; however, little...
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Impact of pre-existing medical conditions on mortality in geriatric trauma: a nationwide study in Japan
PurposeTo investigate the relationship between pre-existing medical conditions and outcomes in elderly trauma patients in Japan.
Methods ... -
Transcatheter aortic valve replacement in patients with a pre-existing prosthetic mitral valve: a single center experience with two cases
BackgroundThe performance of transcatheter aortic valve replacement (TAVR) in patients with pre-existing prosthetic mitral valves is technically...
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Health-related quality of life among cancer survivors: pre-existing chronic conditions are to be given priority
PurposeThis study aimed to describe the health-related quality of life (HRQoL) of cancer survivors in China by the five-level EuroQol-5-dimension...
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Clinical impact of pre-existing acute exacerbation in patients with interstitial lung disease who underwent lung transplantation
BackgroundAcute exacerbation of interstitial lung disease (AE-ILD) significantly impacts prognosis, leading to high mortality rates. Although lung...
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Pre-existing chronic kidney disease, aetiology of acute kidney injury and infection do not affect renal outcome and mortality
BackgroundWe aimed to study the role of aetiology, pre-existing chronic kidney disease (CKD) and infections in acute kidney injury (AKI) on renal...
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Mortality after paediatric emergency calls for patients with or without pre-existing comorbidity: a nationwide population based cohort study
BackgroundLife-threatening conditions are infrequent in children. Current literature in paediatric prehospital research is centred around trauma and...
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Mortality and rehospitalization in patients with pre-existing implantable pacemakers undergoing catheter ablation are related to increased comorbidity burden—data from the German Ablation Registry
BackgroundCatheter ablation of atrial fibrillation and atrial flutter is routinely performed in patients with implantable devices. The aim of the...
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Trastuzumab in patients with breast cancer and pre-existing left ventricular systolic dysfunction
BackgroundTrastuzumab is one of the most effective treatments in HER-2 positive breast cancer patients. However, it is associated with development of...
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Immune-checkpoint inhibitor use in patients with cancer and pre-existing autoimmune diseases
Immune-checkpoint inhibitors (ICIs) have dramatically changed the management of advanced cancers. Designed to enhance the antitumour immune response,...
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Diabetes and COVID-19 Considerations and Clinical Management
Managing COVID-19 alone can be a difficult in many cases, but for persons with pre-existing conditions such as diabetes the challenge can be all the... -
Antidepressant treatment in pregnancy: a Danish registry linkage study in pregnant women with pre-existing obsessive‐compulsive disorder
The association between antidepressant continuation during pregnancy and postpartum mental health in women with obsessive-compulsive disorder (OCD)...
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Does new onset and pre-existing atrial fibrillation predict mortality in COVID-19 patients?
BackgroundCoronavirus Disease-2019 (COVID-19), caused by Severe Acute Respiratory Syndrome-Coronavirus-2, still remains prevalent and severe. We...
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Pre-existing hypertension is associated with poor progression-free survival in newly diagnosed multiple myeloma patients
Approximately 31% of patients diagnosed with multiple myeloma (MM) have pre-existing hypertension, but its effects on patient survival have not been...
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Is compromised intestinal barrier integrity responsible for the poor prognosis in critically ill patients with pre-existing hyperglycemia?
BackgroundCompromised intestinal barrier integrity can be independently driven by hyperglycemia, and both hyperglycemia and intestinal barrier injury...