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Adjuvant Therapy for Patients with a Tumor-Positive Resection Margin After Neoadjuvant Chemoradiotherapy and Esophagectomy
BackgroundApproximately 4–9% of patients have a tumor-positive resection margin after neoadjuvant chemoradiotherapy (nCRT) and esophagectomy....
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Impact of dysplasia at resection margin on oncologic outcome after curative resection of oral tongue squamous cell carcinoma: significance of high-grade dysplastic resection margin
BackgroundThis study aimed to compare the oncologic outcomes among negative, close, positive, and dysplasia resection margins (RMs) with oral tongue...
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Does a Positive Appendiceal Resection Margin in Low-Grade Appendiceal Mucinous Neoplasms, Warrant Additional Surgery? Our Institution Experience and Literature Review
BackgroundManagement of low-grade appendiceal mucinous neoplasm (LAMN) with positive resection margin is controversial. Some guidelines recommend...
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Risk factors for positive resection margins after endoscopic resection for gastrointestinal neuroendocrine tumors
BackgroundIn recent years, the incidence of gastrointestinal neuroendocrine tumors (GI-NETs) has remarkably increased due to the widespread use of...
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Prognostic impact of R1 resection margin in synchronous and simultaneous colorectal liver metastasis resection: a retrospective cohort study
BackgroundA margin ≥ 1 mm is considered a standard resection margin for colorectal liver metastasis (CRLM). However, microscopic incomplete resection...
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Resection status and margin control in intraoperative frozen sectioning analysis of oral squamous cell carcinoma
PurposeIntraoperative frozen section analysis (IFSA) is a well-established procedure for determining the intraoperative soft tissue resection status...
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Risk Factors of Positive Resection Margin in Hepatectomy for Resectable Ruptured Hepatocellular Carcinoma: Risk Prediction and Prognosis
Background and AimClinical work has revealed that hepatectomy for resectable ruptured hepatocellular carcinoma (rHCC) has a relatively high...
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Positive circumferential resection margin in locally advanced esophageal cancer: an updated systematic review and meta-analysis
BackgroundThe impact of positive circumferential resection margin on prognosis in esophageal cancer is under controversy. Previous systematic reviews...
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Clinicopathological Predictors of Positive Resection Margins in Breast-Conserving Surgery
BackgroundDuctal carcinoma in situ (DCIS) is associated with risk of positive resection margins following breast-conserving surgery (BCS) and...
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Residual biliary intraepithelial neoplasia without malignant transformation at resection margin for perihilar cholangiocarcinoma does not require expanded resection: a dual center retrospective study
BackgroundAdditional resection for invasive cancer at perihilar cholangiocarcinoma (pCCA) resection margins has become a consensus. However,...
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A multiparameter MRI-radiomics and clinical nomogram to predict the positive circumferential resection margin of rectal carcinoma
PurposeTo construct a predictive nomogram combining multi-parameter MRI-based radiomics and clinical information to evaluate the circumferential...
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A systematic review of minimal length of lroximal margin in gastric adenocarcinoma resection
SummaryFor early distal gastric cancers, a proximal margin (PM) > 2–3 cm might probably be sufficient. For advanced tumors, many confounding factors...
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The correlation between the margin of resection and prognosis in esophagogastric junction adenocarcinoma
Adenocarcinoma of the gastroesophageal junction (AEG) has become increasingly common in Western and Asian populations. Surgical resection is the...
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Impact of resection margin on outcome in soft-tissue sarcomas of the extremities treated with limb-sparing surgery and postoperative radiotherapy
BackgroundThe standard curative treatments for extremity soft tissue sarcoma (ESTS) include surgical resection with negative margins and...
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Surgical resection margin for T3–T4 primary acral melanoma: a multicenter retrospective cohort study
Although the National Comprehensive Cancer Network (NCCN) guidelines include clear recommendations for the appropriate resection margins in non-acral...
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Prognostic Relevance of the Proximal Resection Margin Distance in Distal Gastrectomy for Gastric Adenocarcinoma
BackgroundThe risk for recurrence in patients with distal gastric cancer can be reduced by surgical radicality. However, dispute exists about the...
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Outcomes of rectal cancer patients with a positive pathological circumferential resection margin
PurposeEvidence-based management of positive pathological circumferential resection margin (pCRM) following preoperative radiation and an adequate...
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The influence of resection margin width in patients with intrahepatic cholangiocarcinoma: a meta-analysis
BackgroundSome studies have pointed out that a wide resection margin can improve the prognosis of intrahepatic cholangiocarcinoma, but some...
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Role of Intraoperative Assessment of Proximal Bile Duct Margin Status and Additional Resection of Perihilar Cholangiocarcinoma: Can Local Clearance Trump Tumor Biology? A Retrospective Cohort Study
BackgroundThe aim of this study was to evaluate the clinical implications of the proximal bile duct margin status in resection of perihilar...
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Breast-Conserving Surgery Margin Guidance Using Micro-Computed Tomography: Challenges When Imaging Radiodense Resection Specimens
BackgroundBreast-conserving surgery (BCS) is an integral component of early-stage breast cancer treatment, but costly reexcision procedures are...
