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Polymerase chain reaction test for diagnosis of infectious uveitis
BackgroundTo study the clinical utility of broad-range real-time Polymerase Chain Reaction (PCR) assay in patients suspected for infectious uveitis...
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Immunohistochemistry and real-time Polymerase Chain Reaction: importance in the diagnosis of intestinal tuberculosis in a Peruvian population
IntroductionThe diagnosis of intestinal tuberculosis is challenging even nowadays. This study aims to report the positivity rates of new diagnostic...
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Detection of urogenital pathogens in sterile pyuria samples by polymerase chain reaction
BackgroundPatients with sterile pyuria may be infected with sexually transmitted diseases or have renal tuberculosis. This study investigated the...
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False negative result of polymerase chain reaction in very early stages of acute retinal necrosis
BackgroundViral nucleic acid testing of intraocular fluid using polymerase chain reaction (PCR) is a major laboratory examination in the diagnosis of...
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Cerebrospinal Fluid Polymerase Chain Reaction in the Diagnosis of Neonatal Bacterial Meningitis: A Single-Center Experience From Vietnam
ObjectiveTo compare the performance of cerebrospinal fluid (CSF) polymerase chain reaction (PCR) with bacterial culture for the diagnosis of neonatal...
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Broad Range Eubacterial Polymerase Chain Reaction of Cerebrospinal Fluid Reduces the Time to Exclusion of and Costs Associated with Ventriculostomy-Related Infection in Hemorrhagic Stroke
BackgroundPatients with hemorrhagic stroke and an external ventricular drain in situ are at risk for ventriculostomy-related-infections (VRI)....
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Bronchoalveolar lavage fluid polymerase chain reaction for invasive pulmonary aspergillosis among high-risk patients: a diagnostic meta-analysis
BackgroundPolymerase chain reaction (PCR) assays are perceived to facilitate the diagnosis of fungal infections. However, due to lack of...
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Comparison of clinician diagnosis of COVID-19 with real time polymerase chain reaction in an adult-representative population in Sweden
BackgroundDue to the high transmissibility of SARS-CoV-2, accurate diagnosis is essential for effective infection control, but the gold standard,...
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Impact of implementation of polymerase chain reaction on diagnosis, treatment, and clinical course of Acanthamoeba keratitis
PurposeAcanthamoeba keratitis (AK) is a painful and possibly sight-threatening ocular infection. While the correct diagnosis and specific treatment...
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Rapid detection and diagnosis of herpetic keratitis using quantitative microfluidic polymerase chain reaction system for herpes simplex and varicella-zoster virus DNA: a case series
BackgroundA microfluidic real-time polymerase chain reaction (PCR) system can rapidly detect the viral DNA in specimens. Detection of herpes simplex...
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Meta-analysis of synovial fluid polymerase chain reaction for diagnosing periprosthetic hip and knee infection
Background and objectiveThe purpose of this study was to estimate the diagnostic performance of synovial fluid polymerase chain reaction (PCR) in...
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Utility of real-time polymerase chain reaction for the assessment of CDKN2A homozygous deletion in adult-type IDH-mutant astrocytoma
The World Health Organization Classification of Tumors of the Central Nervous System 5th Edition (WHO CNS5) introduced a newly defined astrocytoma, IDH ...
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Serum Cytomegalovirus Polymerase Chain Reaction Test Is a Valuable Negative Predictor of Infection in Acute Severe Ulcerative Colitis
BackgroundDiagnosis of cytomegalovirus (CMV) colitis in the setting of severe ulcerative colitis (UC) remains a clinical challenge. This study aimed...
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Occurrence of gastrointestinal nematodes in lambs in Norway, as assessed by copromicroscopy and droplet digital polymerase chain reaction
BackgroundGastrointestinal nematodes (GINs) have a major impact on sheep production, health, and welfare worldwide. Norway is no exception, but there...
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Polymerase chain reaction confirmed mycobacterium tuberculosis intermediate uveitis – analysis of 22 eyes of 14 cases from a tertiary care centre in South India: a retrospective study
BackgroundTo report the role of Polymerase Chain Reaction in confirming the diagnosis of presumed Mycobacterium Tuberculosis (MTB) Intermediate...
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Home urinary tract infection testing: patient experience and satisfaction with polymerase chain reaction kit
Introduction and hypothesisWe sought to evaluate patient satisfaction with a novel multiplex PCR UTI home collection kit for symptomatic UTI in a...
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Comparison of a novel antigen detection test with reverse transcription polymerase chain reaction assay for laboratory diagnosis of SARS-CoV-2 infection
Molecular diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by real-time reverse transcription polymerase chain reaction...
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Molecular detection of Cystoisospora belli by single-run polymerase chain reaction in stool samples
IntroductionCystoisospora belli ( C. belli ) is the only pathogenic species of the Cystoisospora genus responsible for severe diarrhea in...
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Evaluation of the accuracy of multiplex polymerase chain reaction in differentiation between bacterial and viral meningitis
BackgroundMeningitis is one of the most dangerous infection affecting children. The need for rapid and accurate diagnosis is mandatory for improving...
