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The role of therapeutic plasma exchange in plasma cell disorders
Therapeutic plasma exchange (TPE) is an extracorporeal technique where patient’s plasma containing pathogenic substances is separated and removed...
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Characteristics and outcomes of COVID-19 in patients with plasma cell dyscrasias during the first Omicron wave in Bei**g since December 2022: a retrospective study at a National Clinical Research Center for Hematologic Disease
The wave of coronavirus disease 2019 (COVID-19) with Omicron variant reached its first peak in Bei**g, China in December 2022. We delineated...
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Quantitative and qualitative assessment of plasma cell dyscrasias in dual-layer spectral CT
ObjectivesVirtual non-calcium (VNCa) images could improve assessment of plasma cell dyscrasias by enhancing visibility of bone marrow. Thus, VNCa...
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Improved Outcome of Primary Plasma Cell Leukemia in the Current Era with the Use of Novel Agents and Autologous Bone Marrow Transplants—A Single Centre Experience
Primary Plasma cell leukemia (pPCL) is an aggressive variant of plasma cell dyscrasias. Diagnostic criteria of plasma cell leukemia were recently...
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Short Research Communication Anti-Spike Antibody Response to COVISHIELD™ (SII-ChAdOx1 nCoV-19) Vaccine in Patients with B-Cell and Plasma Cell Malignancies and Hematopoietic Cell Transplantation Recipients
IntroductionThere is limited data on the serologic antibody responses after the ChAdOx1 vaccine in patients with hematological malignancies and...
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Idiopathic Lympho-Plasma Cellular Mucositis; A Diagnostic Predicament
The term “idiopathic lymphoplasmacellular mucositis” (ILPM) refers to a set of conditions marked by extensive lymphocyte and plasma cell infiltrates...
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Non-invasive prenatal test identifies circulating cell-free DNA chromosomal abnormalities derived from clonal hematopoiesis in aggressive hematological malignancies
Liquid biopsy is a minimally invasive diagnostic tool for identification of tumor-related mutations in circulating cell-free DNA (cfDNA). The aim of...
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AL Lambda Amyloidosis Activates Acute Liver Failure in the Absence of Plasma Cell Dyscrasia
A patient with systemic amyloidosis developed portal hypertension, acute liver failure and multiorgan dysfunction. Extensive testing was unrevealing...
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Interleukin-6 Blockade with Tocilizumab in Idiopathic Multicentric Plasma Cell Variant Castleman Disease: Case Report
Castleman disease represents a group of rare lymphoproliferative disorders with heterogeneous manifestations and similar histopathological features....
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Occurrence of Monoclonal Band in Alpha Region on Serum Electrophoresis in Multiple Myeloma: A Diagnostic Conundrum
The presence of an M-band in serum and/or urine electrophoresis is a crucial diagnostic indicator for multiple myeloma and other plasma cell...
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Cerebral Infarction as the First Manifestation of Multiple Myeloma and AL Amyloidosis: a Case Report
Multiple myeloma and AL (amyloid light chain) amyloidosis refer to plasma cell abnormalities, with multiple organs being affected, most commonly the...
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SRRM2 may be a potential biomarker and immunotherapy target for multiple myeloma: a real-world study based on flow cytometry detection
Serine/arginine repetitive matrix 2 (SRRM2) has been implicated in tumorigenesis, cancer development, and drug resistance through aberrant splicing;...
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Immunophenotypic Characterization and Ploidy Analysis of Neoplastic Plasma Cells by Multiparametric Flow Cytometry
Flow cytometric (FCM) immunophenoty** is an important tool for generating diagnostic and prognostic information in plasma cell dyscrasias. This...
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Oral Cavity: an Inception to Diagnose Plasma Cell Myeloma. Case Report and Literature Review
Plasma cell myeloma (PCM) is a malignant disease of monoclonal plasma cells which is multicentric in origin. The accurate diagnosis demands...
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Clinically relevant germline variants in allogeneic hematopoietic stem cell transplant recipients
Allogeneic hematopoietic stem cell transplantation (HSCT) provides patients with severe hematologic disease a well-established potential for...
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Lupus mastitis with predominant kappa-restricted plasma cell infiltration: report of a rare case
Lupus mastitis (LM) is a rare complication of systemic lupus erythematosus (SLE) or discoid lupus erythematosus (DLE). The clinical presentations of...
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The effect of red blood cell disorders on male fertility and reproductive health
Male infertility is defined as a failure to conceive after 12 months of unprotected intercourse owing to suspected male reproductive factors....
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Biological properties of bone marrow plasma cells influence their recovery in aspirate specimens: impact on classification of plasma cell disorders and potential bias to evaluation of treatment response
Methods to estimate bone marrow plasma cells (BMPC) basically include histopathology, cytomorphology, and flow cytometry. The present study compares...
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Review of diffusion-weighted imaging and dynamic contrast–enhanced MRI for multiple myeloma and its precursors (monoclonal gammopathy of undetermined significance and smouldering myeloma)
The last decades, increasing research has been conducted on dynamic contrast–enhanced and diffusion-weighted MRI techniques in multiple myeloma and...
