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Inhibitory Effect and Mechanism upon Glucose-Insulin-Potassium Administration on Postpartum Mice with Uterine Cram** Pain
This study aimed to explore the effect of glucose-insulin-potassium (GIK) on postpartum uterine cram** pain(UCP) in mice and the possible...
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Integrating animal experiments, mass spectrometry and network-based approach to reveal the sleep-improving effects of Ziziphi Spinosae Semen and γ-aminobutyric acid mixture
BackgroundZiziphi Spinosae Semen (ZSS) is a plant widely used as medicine and food in Asian countries due to its numerous health benefits....
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Research progress of metabolomics in cervical cancer
IntroductionCervical cancer threatens women's health seriously. In recent years, the incidence of cervical cancer is on the rise, and the age of...
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Application of metabolomics in intrahepatic cholestasis of pregnancy: a systematic review
BackgroundIntrahepatic cholestasis of pregnancy (ICP) is a severe idiopathic disorder of bile metabolism; however, the etiology and pathogenesis of...
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Role of metabolomic profile as a potential marker to discriminate membranous nephropathy from IgA nephropathy
BackgroundMembranous nephropathy (MN) and IgA nephropathy (IgAN) are the most common primary glomerulopathies worldwide. The systemic metabolic...
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Changes in the composition of the fecal metabolome and gut microbiota contribute to intervertebral disk degeneration in a rabbit model
PurposeLower back pain (LBP), mainly caused by intervertebral disk (IVD) degeneration (IDD), is widely prevalent worldwide and is a serious...
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The preliminary investigation of potential response biomarkers to PAHs exposure on childhood asthma
BackgroundExposure to polycyclic aromatic hydrocarbons (PAHs) is a potential risk factor for asthma prevalence. This study aims to explore whether...
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Effect of chemically synthesized psilocybin and psychedelic mushroom extract on molecular and metabolic profiles in mouse brain
Psilocybin, a naturally occurring, tryptamine alkaloid prodrug, is currently being investigated for the treatment of a range of psychiatric...
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Treatment of corn with lactic acid or hydrochloric acid modulates the rumen and plasma metabolic profiles as well as inflammatory responses in beef steers
BackgroundHigh-grain diets that meet the energy requirements of high-producing ruminants are associated with a high risk of rumen disorders. Mild...
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China nationwide landscape of 16 types inherited metabolic disorders: a retrospective analysis on 372,255 clinical cases
BackgroundInherited metabolic disorders (IMDs) usually occurs at young age and hence it severely threatening the health and life of young people....
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Fermented foods and gastrointestinal health: underlying mechanisms
Although fermentation probably originally developed as a means of preserving food substrates, many fermented foods (FFs), and components therein, are...
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Virulence factors and mechanisms of paediatric pneumonia caused by Enterococcus faecalis
Paediatric pneumonia is a respiratory infection that affects infants and young children under the age of 3. This disease is the leading cause of...
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Metabolomics facilitates the discovery of metabolic profiles and pathways for myopia: A systematic review
BackgroundMyopia is one of the major eye disorders and the global burden is increasing rapidly. Our purpose is to systematically summarize potential...
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Network module analysis and molecular docking-based study on the mechanism of astragali radix against non-small cell lung cancer
BackgroundMost lung cancer patients worldwide (stage IV non-small cell lung cancer, NSCLC) have a poor survival: 25%-30% patients die < 3 months....
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Serum and fecal profiles of aromatic microbial metabolites reflect gut microbiota disruption in critically ill patients: a prospective observational pilot study
BackgroundHigh serum levels of certain aromatic microbial metabolites (AMM) are associated with severity and mortality in critically ill patients....
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A novel method for determining postmortem interval based on the metabolomics of multiple organs combined with ensemble learning techniques
Determining postmortem interval (PMI) is one of the most challenging and essential endeavors in forensic science. Developments in PMI estimation can...
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Linking the relation between gut microbiota and glucocorticoid-induced osteoporosis
Osteoporosis (OP) is the most prevalent metabolic bone disease, characterized by the low bone mass and microarchitectural deterioration of bone...
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Metabolomics in Advanced Liver Disease
Purpose of reviewCirrhosis is one of the most important global public health problems. Patients with cirrhosis risk progression to acute-on-chronic...
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A Systematic Review on the Feasibility of Salivary Biomarkers for Alzheimer’s Disease
Early AD diagnosis is critical for ameliorating prognosis and treatment. The analysis of CSF biomarkers yields accurate results, but it necessitates...
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Salivary metabolites to detect patients with cancer: a systematic review
Novel adjunctive screening aids are needed to reduce the morbidity and mortality related to cancer, and every effort should be made for early...
